Literature DB >> 34964687

From "Hunger Hormone" to "It's Complicated": Ghrelin Beyond Feeding Control.

Sara L Deschaine1, Lorenzo Leggio1,2,3,4,5.   

Abstract

Discovered as a peptide involved in releasing growth hormone, ghrelin was initially characterized as the "hunger hormone." However, emerging research indicates that ghrelin appears to play an important part in relaying information regarding nutrient availability and value and adjusting physiological and motivational processes accordingly. These functions make ghrelin an interesting therapeutic candidate for metabolic and neuropsychiatric diseases involving disrupted nutrition that can further potentiate the rewarding effect of maladaptive behaviors.

Entities:  

Keywords:  ghrelin

Mesh：

Substances：

Year:  2022        PMID： 34964687      PMCID： PMC8742734          DOI： 10.1152/physiol.00024.2021

Source DB:  PubMed          Journal:  Physiology (Bethesda)        ISSN： 1548-9221


  130 in total

1.  Ghrelin stimulates locomotor activity and accumbal dopamine-overflow via central cholinergic systems in mice: implications for its involvement in brain reward.

Authors:  Elisabet Jerlhag; Emil Egecioglu; Suzanne L Dickson; Malin Andersson; Lennart Svensson; Jörgen A Engel
Journal:  Addict Biol       Date:  2006-03       Impact factor: 4.280

2.  Increased affinity of ghrelin-reactive immunoglobulins in obese Zucker rats.

Authors:  Nicolas Lucas; Romain Legrand; Jonathan Breton; Pierre Déchelotte; Sergueï O Fetissov
Journal:  Nutrition       Date:  2016-12-11       Impact factor: 4.008

Review 3.  Stress and obesity: The ghrelin connection.

Authors:  Alfonso Abizaid
Journal:  J Neuroendocrinol       Date:  2019-02-19       Impact factor: 3.627

4.  Ghrelin stimulates gastric emptying and hunger in normal-weight humans.

Authors:  F Levin; T Edholm; P T Schmidt; P Grybäck; H Jacobsson; M Degerblad; C Höybye; J J Holst; J F Rehfeld; P M Hellström; E Näslund
Journal:  J Clin Endocrinol Metab       Date:  2006-06-13       Impact factor: 5.958

5.  Variations in postprandial ghrelin status following ingestion of high-carbohydrate, high-fat, and high-protein meals in males.

Authors:  Dalia Tannous dit El Khoury; Omar Obeid; Sami T Azar; Nahla Hwalla
Journal:  Ann Nutr Metab       Date:  2006-02-23       Impact factor: 3.374

6.  Structure-activity relationships of a synthetic pentapeptide that specifically releases growth hormone in vitro.

Authors:  C Y Bowers; F Momany; G A Reynolds; D Chang; A Hong; K Chang
Journal:  Endocrinology       Date:  1980-03       Impact factor: 4.736

7.  Structural and functional analysis of human liver-expressed antimicrobial peptide 2.

Authors:  Sónia Troeira Henriques; Chia Chia Tan; David J Craik; Richard J Clark
Journal:  Chembiochem       Date:  2010-10-18       Impact factor: 3.164

8.  Ghrelin directly targets the ventral tegmental area to increase food motivation.

Authors:  K P Skibicka; C Hansson; M Alvarez-Crespo; P A Friberg; S L Dickson
Journal:  Neuroscience       Date:  2011-02-16       Impact factor: 3.590

9.  Ghrelin octanoylation mediated by an orphan lipid transferase.

Authors:  Jesus A Gutierrez; Patricia J Solenberg; Douglas R Perkins; Jill A Willency; Michael D Knierman; Zhaoyan Jin; Derrick R Witcher; Shuang Luo; Jude E Onyia; John E Hale
Journal:  Proc Natl Acad Sci U S A       Date:  2008-04-28       Impact factor: 11.205

10.  Role of ghrelin in food reward: impact of ghrelin on sucrose self-administration and mesolimbic dopamine and acetylcholine receptor gene expression.

Authors:  Karolina P Skibicka; Caroline Hansson; Emil Egecioglu; Suzanne L Dickson
Journal:  Addict Biol       Date:  2011-02-11       Impact factor: 4.280
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  1 in total

Review 1.  Chrono-communication and cardiometabolic health: The intrinsic relationship and therapeutic nutritional promises.

Authors:  Pamela Senesi; Anna Ferrulli; Livio Luzi; Ileana Terruzzi
Journal:  Front Endocrinol (Lausanne)       Date:  2022-09-13       Impact factor: 6.055
  1 in total

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