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Literature DB >> 3496136

CFU-F circulating in cord blood.

G Prindull, Z Ben-Ishay, W Ebell, M Bergholz, T Dirk, B Prindull.

Abstract

CFU-F (colony forming units-fibroblast) were studied from cord blood and, as controls, from normal bone marrow of older children and adults. Numbers of CFU-F in cord blood buffy coat cells are lower by a factor of 10 in comparison to bone marrow CFU-F. Cytomorphology and staining with monoclonal antibody identify the progeny cells of CFU-F as fibroblasts. Cord blood CFU-F derived fibroblasts have properties supporting hematopoiesis: They produce CSF (colony stimulating factor) to which fresh cord blood CFU-GM (colony forming units-granulocytic, monocytic) react by colony formation in a dose-response manner. In addition, fibroblast colonies discharge clonogenic round cells into the medium forming CFU-GM and CFU-F colonies in secondary methyl cellulose cultures. We conclude that fetal blood contains clonogenic stromal cells (CFU-F) that give rise to fibroblasts with properties of hematopoietic support.

Entities: Chemical Disease Gene Species

Mesh：

Substances：

Year: 1987 PMID： 3496136 DOI： 10.1007/BF00626017

Source DB: PubMed Journal: Blut ISSN： 0006-5242

37 in total

1. Formation in agar of fibroblast-like colonies by cells from the mouse pleural cavity and other sources.

Authors: D Metcalf
Journal: J Cell Physiol Date: 1972-12 Impact factor: 6.384

2. Characterization of canine fetal lymphohematopoiesis: studies of CFUGM, CFUL, and CFUF.

Authors: A K Klein; J A Dyck; K A Stitzel; J Shimizu; L A Fox; N Taylor
Journal: Exp Hematol Date: 1983-04 Impact factor: 3.084

3. Morphological studies on 'adherent cells' in bone marrow cultures from humans, dogs, and mice.

Authors: F D Wilson; M Tavassoli; B R Greenberg; D Hinds; A K Klein
Journal: Stem Cells Date: 1981 Impact factor: 6.277

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Authors: G Prindull; B Prindull; N Meulen
Journal: Acta Paediatr Scand Date: 1978-07

5. The origin of the hematopoietic microenvironment in continuous bone marrow culture.

Authors: S A Bentley; T Knutsen; J Whang-Peng
Journal: Exp Hematol Date: 1982-04 Impact factor: 3.084

6. Characterization of human bone marrow fibroblast colony-forming cells (CFU-F) and their progeny.

Authors: H Castro-Malaspina; R E Gay; G Resnick; N Kapoor; P Meyers; D Chiarieri; S McKenzie; H E Broxmeyer; M A Moore
Journal: Blood Date: 1980-08 Impact factor: 22.113

7. Migration of fibroblastoid stromal cells in murine blood.

Authors: A H Piersma; R E Ploemacher; K G Brockbank; P G Nikkels; C P Ottenheim
Journal: Cell Tissue Kinet Date: 1985-11

8. Circulating haematopoietic stem cells (CFUc) in healthy and diseased pre-term infants.

Authors: G Prindull; M Albani; B Prindull; W Schröter
Journal: Scand J Haematol Date: 1980-09

9. A monokine regulates colony-stimulating activity production by vascular endothelial cells.

Authors: G C Bagby; E McCall; K A Bergstrom; D Burger
Journal: Blood Date: 1983-09 Impact factor: 22.113

10. In vitro analysis of the contributions of adherent cell layer and recharging population to hemopoietic cell proliferation in long-term bone marrow cultures.

Authors: I Fabian; M Cline
Journal: Exp Hematol Date: 1981-04 Impact factor: 3.084

4 in total

Review 4. The Role of Mesenchymal Stem Cells in Atherosclerosis: Prospects for Therapy via the Modulation of Inflammatory Milieu.

Authors: Armita Mahdavi Gorabi; Maciej Banach; Željko Reiner; Matteo Pirro; Saeideh Hajighasemi; Thomas P Johnston; Amirhossein Sahebkar
Journal: J Clin Med Date: 2019-09-08 Impact factor: 4.241