Literature DB >> 34959677

29th Annual GP2A Medicinal Chemistry Conference.

Jean-Jacques Helesbeux1, Laura Carro2, Florence O McCarthy3, Vânia M Moreira4,5, Francesca Giuntini6, Niamh O'Boyle7, Susan E Matthews8, Gülşah Bayraktar9, Samuel Bertrand10, Christophe Rochais11, Pascal Marchand12.   

Abstract

The 29th Annual GP2A (Group for the Promotion of Pharmaceutical chemistry in Academia) Conference was a virtual event this year due to the COVID-19 pandemic and spanned three days from Wednesday 25 to Friday 27 August 2021. The meeting brought together an international delegation of researchers with interests in medicinal chemistry and interfacing disciplines. Abstracts of keynote lectures given by the 10 invited speakers, along with those of the 8 young researcher talks and the 50 flash presentation posters, are included in this report. Like previous editions, the conference was a real success, with high-level scientific discussions on cutting-edge advances in the fields of pharmaceutical chemistry.

Entities:  

Keywords:  chemical biology; chemical tools; drug design; medicinal chemistry; molecular pharmacology; pharmaceutical chemistry

Year:  2021        PMID: 34959677      PMCID: PMC8708472          DOI: 10.3390/ph14121278

Source DB:  PubMed          Journal:  Pharmaceuticals (Basel)        ISSN: 1424-8247


  164 in total

1.  Inhibition of myeloperoxidase: evaluation of 2H-indazoles and 1H-indazolones.

Authors:  Aaron Roth; Sean Ott; Kelli M Farber; Teresa A Palazzo; Wayne E Conrad; Makhluf J Haddadin; Dean J Tantillo; Carroll E Cross; Jason P Eiserich; Mark J Kurth
Journal:  Bioorg Med Chem       Date:  2014-10-02       Impact factor: 3.641

2.  Tyrosine kinase inhibitors: Multi-targeted or single-targeted?

Authors:  Fleur Broekman; Elisa Giovannetti; Godefridus J Peters
Journal:  World J Clin Oncol       Date:  2011-02-10

3.  Nongenotoxic 3-Nitroimidazo[1,2-a]pyridines Are NTR1 Substrates That Display Potent in Vitro Antileishmanial Activity.

Authors:  Cyril Fersing; Louise Basmaciyan; Clotilde Boudot; Julien Pedron; Sébastien Hutter; Anita Cohen; Caroline Castera-Ducros; Nicolas Primas; Michèle Laget; Magali Casanova; Sandra Bourgeade-Delmas; Mélanie Piednoel; Alix Sournia-Saquet; Valère Belle Mbou; Bertrand Courtioux; Élisa Boutet-Robinet; Marc Since; Rachel Milne; Susan Wyllie; Alan H Fairlamb; Alexis Valentin; Pascal Rathelot; Pierre Verhaeghe; Patrice Vanelle; Nadine Azas
Journal:  ACS Med Chem Lett       Date:  2018-12-19       Impact factor: 4.345

4.  Inhibition of both focal adhesion kinase and insulin-like growth factor-I receptor kinase suppresses glioma proliferation in vitro and in vivo.

Authors:  Ta-Jen Liu; Tiffany LaFortune; Toshiyuki Honda; Osamu Ohmori; Shinji Hatakeyama; Thomas Meyer; Dowdy Jackson; John de Groot; W K Alfred Yung
Journal:  Mol Cancer Ther       Date:  2007-04       Impact factor: 6.261

5.  Efficient Access to All-Carbon Quaternary and Tertiary α-Functionalized Homoallyl-type Aldehydes from Ketones.

Authors:  Vittorio Pace; Laura Castoldi; Eugenia Mazzeo; Marta Rui; Thierry Langer; Wolfgang Holzer
Journal:  Angew Chem Int Ed Engl       Date:  2017-09-01       Impact factor: 15.336

6.  Antikinetoplastid SAR study in 3-nitroimidazopyridine series: Identification of a novel non-genotoxic and potent anti-T. b. brucei hit-compound with improved pharmacokinetic properties.

Authors:  Cyril Fersing; Clotilde Boudot; Romain Paoli-Lombardo; Nicolas Primas; Emilie Pinault; Sébastien Hutter; Caroline Castera-Ducros; Youssef Kabri; Julien Pedron; Sandra Bourgeade-Delmas; Alix Sournia-Saquet; Jean-Luc Stigliani; Alexis Valentin; Amaya Azqueta; Damián Muruzabal; Alexandre Destere; Susan Wyllie; Alan H Fairlamb; Sophie Corvaisier; Marc Since; Aurélie Malzert-Fréon; Carole Di Giorgio; Pascal Rathelot; Nadine Azas; Bertrand Courtioux; Patrice Vanelle; Pierre Verhaeghe
Journal:  Eur J Med Chem       Date:  2020-08-04       Impact factor: 6.514

7.  Targeting the tumour microenvironment with an enzyme-responsive drug delivery system for the efficient therapy of breast and pancreatic cancers.

Authors:  Brigitte Renoux; Florian Raes; Thibaut Legigan; Elodie Péraudeau; Balkis Eddhif; Pauline Poinot; Isabelle Tranoy-Opalinski; Jérôme Alsarraf; Oleksandr Koniev; Sergii Kolodych; Stéphanie Lerondel; Alain Le Pape; Jonathan Clarhaut; Sébastien Papot
Journal:  Chem Sci       Date:  2017-03-08       Impact factor: 9.825

Review 8.  Engineering precision nanoparticles for drug delivery.

Authors:  Michael J Mitchell; Margaret M Billingsley; Rebecca M Haley; Marissa E Wechsler; Nicholas A Peppas; Robert Langer
Journal:  Nat Rev Drug Discov       Date:  2020-12-04       Impact factor: 84.694

Review 9.  Role of nitric oxide in the gastrointestinal tract.

Authors:  Angel Lanas
Journal:  Arthritis Res Ther       Date:  2008-10-17       Impact factor: 5.156

10.  STITCH 5: augmenting protein-chemical interaction networks with tissue and affinity data.

Authors:  Damian Szklarczyk; Alberto Santos; Christian von Mering; Lars Juhl Jensen; Peer Bork; Michael Kuhn
Journal:  Nucleic Acids Res       Date:  2015-11-20       Impact factor: 16.971

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