INTRODUCTION: This report examines between- and within-person associations between youth irritability and concurrent and prospective internalizing and externalizing symptoms from early childhood through adolescence. Distinguishing between- and within-person longitudinal associations may yield distinct, clinically relevant information about pathways to multifinality from childhood irritability. METHODS: Children's irritability and co-occurring symptoms were assessed across five waves between ages 3 and 15 years using the mother-reported Child Behavior Checklist (N = 605, 46% female). Parental history of depressive disorders was assessed with a clinical interview. RESULTS: Results demonstrated that between- and within-person irritability were uniquely associated with concurrent depressive, anxiety, and defiance symptoms, but not ADHD. Prior wave within-person irritability also predicted next wave depressive, anxiety, and defiance symptoms, controlling for prior symptoms; these prospective associations were bidirectional. Child sex and parental depressive disorders moderated associations. DISCUSSIONS: Findings identify pathways from within- and between-person irritability to later internalizing and externalizing psychopathology. Results demonstrate the importance of parsing within- and between-person effects to understand nuanced relations among symptoms over childhood.
INTRODUCTION: This report examines between- and within-person associations between youth irritability and concurrent and prospective internalizing and externalizing symptoms from early childhood through adolescence. Distinguishing between- and within-person longitudinal associations may yield distinct, clinically relevant information about pathways to multifinality from childhood irritability. METHODS: Children's irritability and co-occurring symptoms were assessed across five waves between ages 3 and 15 years using the mother-reported Child Behavior Checklist (N = 605, 46% female). Parental history of depressive disorders was assessed with a clinical interview. RESULTS: Results demonstrated that between- and within-person irritability were uniquely associated with concurrent depressive, anxiety, and defiance symptoms, but not ADHD. Prior wave within-person irritability also predicted next wave depressive, anxiety, and defiance symptoms, controlling for prior symptoms; these prospective associations were bidirectional. Child sex and parental depressive disorders moderated associations. DISCUSSIONS: Findings identify pathways from within- and between-person irritability to later internalizing and externalizing psychopathology. Results demonstrate the importance of parsing within- and between-person effects to understand nuanced relations among symptoms over childhood.
Authors: Roxann Roberson-Nay; Ellen Leibenluft; Melissa A Brotman; John Myers; Henrik Larsson; Paul Lichtenstein; Kenneth S Kendler Journal: Am J Psychiatry Date: 2015-04-23 Impact factor: 18.112
Authors: Mariah T Hawes; Gabrielle A Carlson; Megan C Finsaas; Thomas M Olino; John R Seely; Daniel N Klein Journal: Psychol Med Date: 2019-10-22 Impact factor: 7.723
Authors: Lea R Dougherty; Victoria C Smith; Sara J Bufferd; Argyris Stringaris; Ellen Leibenluft; Gabrielle A Carlson; Daniel N Klein Journal: J Am Acad Child Adolesc Psychiatry Date: 2013-09-26 Impact factor: 8.829
Authors: Lea R Dougherty; Victoria C Smith; Sara J Bufferd; Ellen Kessel; Gabrielle A Carlson; Daniel N Klein Journal: J Child Psychol Psychiatry Date: 2015-02-27 Impact factor: 8.982