| Literature DB >> 34952626 |
Amy L Xu1, Alexandra M Dunham1, Zachary O Enumah2, Casey J Humbyrd3.
Abstract
BACKGROUND: Prior studies have assessed provider knowledge and factors associated with opioid misuse; similar studies evaluating patient knowledge are lacking. The purpose of this study was to assess the degree of understanding regarding opioid use in orthopaedic trauma patients. We also sought to determine the demographic factors and clinical and personal experiences associated with level of understanding.Entities:
Keywords: Addiction; Dependence; Naloxone; Opioid misuse; Patient knowledge
Mesh:
Substances:
Year: 2021 PMID: 34952626 PMCID: PMC8709537 DOI: 10.1186/s13018-021-02881-w
Source DB: PubMed Journal: J Orthop Surg Res ISSN: 1749-799X Impact factor: 2.359
Characteristics of 166 patients presenting to orthopaedic trauma surgery clinics
| Patient characteristics | ||
|---|---|---|
| Characteristics | No. of respondents | %a |
| Demographics | ||
| Female | 111 | 67 |
| Male | 52 | 31 |
| No answer | 3 | 1.8 |
| 18–24 | 5 | 3.0 |
| 25–34 | 28 | 17 |
| 35–44 | 19 | 11 |
| 45–54 | 33 | 20 |
| 55–64 | 42 | 25 |
| 65–74 | 32 | 19 |
| 75–84 | 3 | 1.8 |
| 85+ | 1 | 0.6 |
| No answer | 2 | 1.2 |
| White | 136 | 82 |
| African American | 15 | 9.0 |
| Asian | 3 | 1.8 |
| Hispanic/Latino | 5 | 3.0 |
| Other | 3 | 1.8 |
| No answer | 4 | 2.4 |
| Insured | 162 | 98 |
| Not insured | 2 | 1.2 |
| No answer | 2 | 1.2 |
| High school or less | 12 | 7.2 |
| Some college | 14 | 8.4 |
| 2-year degree | 6 | 3.6 |
| 4-year degree | 49 | 30 |
| Graduate school or higher | 82 | 49 |
| No answer | 3 | 1.8 |
| Full-time | 84 | 51 |
| Part-time | 6 | 3.6 |
| Unemployed | 17 | 10 |
| Retired | 35 | 21 |
| Disabled | 14 | 8.4 |
| Student | 4 | 2.4 |
| No answer | 3 | 1.8 |
| Married | 96 | 58 |
| Never married | 34 | 20 |
| Divorced | 25 | 15 |
| Widowed | 7 | 4.2 |
| No answer | 4 | 2.4 |
| 1 | 60 | 36 |
| 2 | 51 | 31 |
| 3 | 27 | 16 |
| 4 | 8 | 4.8 |
| No answer | 20 | 12 |
| Clinical and personal experiences | ||
| Acute injury/accident/problem < 2 weeks | 13 | 7.8 |
| Subacute injury/accident/problem > 2 weeks | 94 | 57 |
| Chronic problem ≥ 1 year | 34 | 20 |
| No answer | 25 | 15 |
| Yes | 153 | 92 |
| No | 12 | 7.2 |
| No answer | 1 | 0.6 |
| Yes | 164 | 99 |
| No | 1 | 0.6 |
| No answer | 1 | 0.6 |
| Yes | 156 | 94 |
| No | 4 | 2.4 |
| No answer | 6 | 3.6 |
| Yes | 18 | 11 |
| No | 138 | 83 |
| No answer | 10 | 6.0 |
| Yes | 5 | 3.0 |
| No | 117 | 70 |
| No answer | 44 | 27 |
| Yes | 16 | 9.6 |
| No | 140 | 84 |
| No answer | 10 | 6.0 |
| Self | 16 | 9.6 |
| Family | 27 | 16 |
| Friend | 35 | 21 |
| Colleague | 2 | 1.2 |
| Client/student/patient/etc. | 4 | 2.4 |
| None | 81 | 49 |
| No answer | 1 | 0.6 |
| Self | 2 | 1.2 |
| Family | 12 | 7.2 |
| Friend | 27 | 16 |
| Colleague | 3 | 1.8 |
| Client/student/patient/etc. | 4 | 2.4 |
| None | 117 | 70 |
| No answer | 1 | 0.6 |
ADI, Area deprivation index
aPercentages may not add to 100 from rounding error
Adjusted (multivariable) odds of orthopaedic trauma surgery patient understanding regarding opioid use
| Parameter | > 85% common opioids | Suboxone/subutex | > 85% side effects | > 85% withdrawal symptoms | Dependence < 2 weeks | OTC x opioid safety | Comfort with naloxone | Addiction discrepancya | Know enough to take safely |
|---|---|---|---|---|---|---|---|---|---|
| Adjusted odds ratio (95% CI) | |||||||||
| Maleb | – | – | – | – | – | – | – | – | – |
| Female | 0.68 (0.26–1.8) | 0.94 (0.37–2.4) | 1.7 (0.38–7.2) | 1.1 (0.44–2.7) | 2.0 (0.76–5.2) | 0.64 (0.22–1.8) | 1.7 (0.69–4.2) | 0.88 (0.25–3.1) | 1.8 (0.28–11) |
| < 65 yearsb | – | – | – | – | – | – | – | – | – |
| ≥ 65 years | 0.38 (0.11–1.3) | 0.42 (0.13–1.3) | 0.13 (0.01–1.3) | 0.63 (0.21–1.9) | 1.3 (0.45–4.0) | 0.77 (0.24–2.5) | 1.1 (0.40–3.0) | 1.2 (0.31–4.3) | 0.97 (0.11–9.0) |
| Whiteb | – | – | – | – | – | – | – | – | – |
| Non-white | 0.50 (0.12–2.1) | 1.1 (0.28–3.9) | 1.5 (0.19–11) | 1.1 (0.29–4.2) | 0.45 (0.13–1.6) | 0.57 (0.15–2.1) | 1.0 (0.30–3.5) | 1.0 | |
| Singleb | – | – | – | – | – | – | – | – | – |
| Married | 0.73 (0.30–1.8) | 2.0 (0.79–4.9) | 1.6 (0.40–6.2) | 1.8 (0.75–4.6) | 1.9 (0.79–4.8) | 0.81 (0.30–2.2) | 0.55 (0.24–1.2) | 1.1 (0.35–3.5) | 2.7 (0.41–17) |
| Unemployedb | – | – | – | – | – | – | – | – | – |
Employed w/ < 4-yr degree | 1.1 (0.37–3.1) | 0.85 (0.30–2.4) | 0.67 (0.16–2.8) | 0.53 (0.19–1.5) | 0.53 (0.19–1.5) | 1.4 (0.46–4.1) | 1.5 (0.58–3.8) | 2.0 (0.55–7.1) | 0.53 (0.06–4.5) |
Employed w/ ≥ 4-yr degree | 1.6 (0.55–4.6) | 1.6 (0.55–4.4) | 0.77 (0.28–2.2) | 0.75 (0.24–2.3) | 0.61 (0.22–1.7) | 0.73 (0.16–3.4) | 1.1 (0.07–17) | ||
| 1b | – | – | – | – | – | – | – | – | – |
| 2 | 0.79 (0.28–2.2) | 2.3 (0.86–6.4) | 1.2 (0.43–3.5) | 0.51 (0.18–1.5) | 1.1 (0.42–2.7) | 1.1 (0.32–4.1) | 0.13 (0.01–1.5) | ||
| 3 + 4 | 0.66 (0.21–2.0) | 1.9 (0.62–5.6) | 6.1 (0.95–39) | 1.5 (0.49–4.4) | 1.1 (0.35–3.3) | 0.53 (0.16–1.8) | 0.65 (0.23–1.9) | 0.72 (0.15–3.4) | 0.41 (0.02–8.0) |
| Acute or subacuteb | – | – | – | – | – | – | – | – | – |
| Chronic | 2.5 (0.79–8.0) | 1.3 (0.42–4.0) | 0.23 (0.03–1.6) | 0.51 (0.15–1.7) | 1.0 (0.31–3.4) | 0.49 (0.14–1.7) | 2.6 (0.89–7.9) | 2.7 (0.67–11) | 1.0 |
| Nob | – | – | – | – | – | – | – | – | – |
| Yes | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 | 1.0 |
| Nob | – | – | – | – | – | – | – | – | – |
| Yes | 1.9 (0.47–8.0) | 0.66 (0.15–2.9) | 1.9 (0.47–8.0) | 0.27 (0.05–1.6) | 0.61 (0.14–2.6) | 1.5 (0.35–6.2) | 0.97 (0.16–6.0) | 1.0 | |
| Nob | – | – | – | – | – | – | – | – | – |
| Yes | 1.3 (0.31–5.2) | 1.3 (0.31–5.1) | 1.3 (0.31–5.2) | 0.73 (0.16–3.3) | 0.90 (0.23–3.5) | 1.8 (0.42–7.9) | 1.8 (0.48–6.9) | 0.82 (0.13–5.2) | 1.0 |
| Nob | – | – | – | – | – | – | – | – | – |
| Yes | 1.9 (0.74–5.0) | 2.2 (0.88–5.7) | 1.9 (0.74–5.0) | 0.78 (0.29–2.1) | 1.5 (0.66–3.5) | 1.8 (0.26–12) | |||
Bold values indicate significant associations between patient characteristics and measures of understanding regarding opioid use
OTC, Over the counter; ADI, area deprivation index
*Significant at p < 0.05
**Significant at p < 0.01
***Significant at p < 0.001
aAddiction discrepancy = patients who believed that others, but not self, can become addicted to opioids
bReferent
Fig. 1Common opioids, side effects, withdrawal symptoms, and disposal methods identified correctly by orthopaedic trauma patients
Understanding regarding opioid use of 166 patients presenting to orthopaedic trauma surgery clinics
| Patient understanding regarding opioid use | ||
|---|---|---|
| Responses | No. of respondents | %a |
| 85%+ correct | 48 | 29 |
| 70–84% | 62 | 37 |
| 55–69% | 38 | 23 |
| < 55% | 18 | 11 |
| No answer | 0 | 0.0 |
| Both | 24 | 14 |
| One | 26 | 16 |
| Neither | 116 | 70 |
| No answer | 0 | 0.0 |
| 85%+ correct | 17 | 10 |
| 70–84% | 18 | 11 |
| 55–69% | 35 | 21 |
| < 55% | 93 | 56 |
| No answer | 3 | 1.8 |
| 85%+ correct | 50 | 30 |
| 70–84% | 32 | 19 |
| 55–69% | 25 | 15 |
| < 55% | 54 | 33 |
| No answer | 5 | 3.0 |
| 85%+ correct | 4 | 2.4 |
| 70–84% | 12 | 7.2 |
| 55–69% | 64 | 39 |
| < 55% | 86 | 52 |
| No answer | 0 | 0.0 |
| < 1 week | 61 | 37 |
| 1–2 weeks | 35 | 21 |
| 2 weeks–1 month | 28 | 17 |
| > 1 month | 28 | 17 |
| No answer | 14 | 8.4 |
| Yes | 59 | 36 |
| No | 60 | 36 |
| No answer | 47 | 28 |
| Extremely comfortable | 40 | 24 |
| Somewhat comfortable | 26 | 16 |
| Neutral | 68 | 41 |
| Somewhat uncomfortable | 17 | 10 |
| Extremely uncomfortable | 13 | 7.8 |
| No answer | 2 | 1.2 |
| 0–2 | 0 | 0.0 |
| 3–4 | 3 | 1.8 |
| 5–6 | 19 | 11 |
| 7–8 | 75 | 45 |
| 9–10 | 53 | 32 |
| No answer | 16 | 9.6 |
| Yes | 140 | 84 |
| No | 19 | 11 |
| No answer | 7 | 4.2 |
| Yes | 165 | 99 |
| No | 0 | 0.0 |
| No answer | 1 | 0.6 |
| Yes | 159 | 96 |
| No | 5 | 3.0 |
| No answer | 2 | 1.2 |
| Yes | 143 | 86 |
| No | 11 | 6.6 |
| No answer | 12 | 7.2 |
OTC, Over the counter
aPercentages may not add to 100 from rounding error