Literature DB >> 34952626

Patient understanding regarding opioid use in an orthopaedic trauma surgery population: a survey study.

Amy L Xu1, Alexandra M Dunham1, Zachary O Enumah2, Casey J Humbyrd3.   

Abstract

BACKGROUND: Prior studies have assessed provider knowledge and factors associated with opioid misuse; similar studies evaluating patient knowledge are lacking. The purpose of this study was to assess the degree of understanding regarding opioid use in orthopaedic trauma patients. We also sought to determine the demographic factors and clinical and personal experiences associated with level of understanding.
METHODS: One hundred and sixty-six adult orthopaedic trauma surgery patients across two clinical sites of an academic institution participated in an internet-based survey (2352 invited, 7.1% response rate). Demographic, clinical, and personal experience variables, as well as perceptions surrounding opioid use were collected. Relationships between patient characteristics and opioid perceptions were identified using univariate and multivariable logistic regressions. Alpha = 0.05.
RESULTS: Excellent recognition (> 85% correct) of common opioids, side effects, withdrawal symptoms, and disposal methods was demonstrated by 29%, 10%, 30%, and 2.4% of patients; poor recognition (< 55%) by 11%, 56%, 33%, and 52% of patients, respectively. Compared with white patients, non-white patients had 7.8 times greater odds (95% confidence interval [CI] 1.9-31) of perceiving addiction discrepancy (p = 0.004). Employed patients with higher education levels were less likely to have excellent understanding of side effects (adjusted odds ratio [aOR] 0.06, 95% CI 0.006-0.56; p = 0.01) and to understand that dependence can occur within 2 weeks (aOR 0.28, 95% CI 0.09-0.86; p = 0.03) than unemployed patients. Patients in the second least disadvantaged ADI quartile were more knowledgeable about side effects (aOR 8.8, 95% CI 1.7-46) and withdrawal symptoms (aOR 2.7, 95% CI 1.0-7.2; p = 0.046) than those in the least disadvantaged quartile. Patients who knew someone who was dependent or overdosed on opioids were less likely to perceive addiction discrepancy (aOR 0.24, 95% CI 0.07-0.76; p = 0.02) as well as more likely to have excellent knowledge of withdrawal symptoms (aOR 2.6, 95% CI 1.1-6.5, p = 0.03) and to understand that dependence can develop within 2 weeks (aOR 3.8, 95% CI 1.5-9.8, p = 0.005).
CONCLUSIONS: Level of understanding regarding opioid use is low among orthopaedic trauma surgery patients. Clinical and personal experiences with opioids, in addition to demographics, should be emphasized in the clinical history.
© 2021. The Author(s).

Entities:  

Keywords:  Addiction; Dependence; Naloxone; Opioid misuse; Patient knowledge

Mesh:

Substances:

Year:  2021        PMID: 34952626      PMCID: PMC8709537          DOI: 10.1186/s13018-021-02881-w

Source DB:  PubMed          Journal:  J Orthop Surg Res        ISSN: 1749-799X            Impact factor:   2.359


Background

The United States has been in the midst of a public health crisis—nearly 70% of the 67,367 drug overdose deaths in 2018 reported involvement of an opioid [1]. Prescription opioid misuse is a recognized patient safety issue within the medical community. Because many patients are first exposed to opioids after undergoing a surgery and surgeons are amongst the highest prescribers of opioids [2, 3], there has been a push within surgical specialties to educate physicians and their patients on the appropriate use of opioids. These efforts have largely targeted prescribing practices to reduce prescription size without increasing the need for refills due to poor pain management [4, 5]. The Centers for Disease Control suggest early successes from such efforts, estimating a 17% decrease in prescription opioid-involved death rates from 2017 to 2019 [1]. However, recent data demonstrate an increase in overall overdose deaths coinciding with the start of the coronavirus disease (COVID-19) pandemic with over 81,000 deaths occurring in the year ending in May 2020 [6]. While there is some improvement in prescription opioid-related deaths, long-term use of opioids after surgery remains high [2, 3]. To aid surgeons in understanding patients’ risk of chronically using opioids, previous studies have assessed factors that may predispose individuals to opioid abuse after procedures [7, 8]. These studies have suggested younger age, female sex, lower income, and specific medical comorbidities (i.e. pre-surgical opioid use, history of substance abuse, and mental health factors) can predispose patients to prolonged opioid use [9-12]. Knowledge of appropriate opioid use is also likely to play a role. Most literature addressing opioid knowledge has focused on providers’ understanding [13-15]. However, the level of patient understanding regarding opioids and their appropriate use has been minimally studied [16-19]. Specifically, opioid knowledge within the orthopaedic trauma patient population, one of the populations most at risk for opioid misuse [10], has not previously been studied. A study within an orthopaedic hand surgery specialty practice revealed that while 80% of patients are aware of the addictive properties of opioids, a substantial proportion also possess inaccurate beliefs, such as believing that opioids work well for controlling long-term pain [20]. Given the evidence of existing knowledge gaps, it is essential to identify the specific shortcomings in patient knowledge and to determine what demographic, clinical, or personal experience factors may be associated with misconceptions of opioid use. This information will provide a foundation on which to base future educational interventions. We therefore sought to assess the degree of understanding regarding opioid use in a consecutive sample of orthopaedic trauma patients and identify knowledge gaps. We also aimed to determine the demographic, clinical, and personal experience factors associated with level of understanding.

Methods

Study design and settings

After institutional review board approval, participants were recruited from orthopaedic surgery trauma clinics at two hospital-based clinical sites within our institution. A consecutive sample of all adult patients (≥ 18 years) who visited the identified clinics between August 2009 and November 2020 were invited to participate via an email from the electronic medical record. Informed consent was obtained prior to administering an anonymous 32-question, voluntary online survey with a 7.4 grade Flesch–Kincaid reading level (“Appendix”) [21, 22]. The survey was created using Qualtrics XM (Seattle, WA, USA) and distributed via the MyChart system (Epic Systems Corporation, Verona, WI) to patients meeting our inclusion criteria, 2352 of whom opened the message. The study was performed using the MyChart system, rather than in-person surveys, due to restrictions on in-person research related to the COVID-19 pandemic. The survey included questions about the following demographic variables: gender, age, race/ethnicity, insurance status, education level, employment status, marital status, and zip code to assess area deprivation index (ADI) quartile [23]. Participants were also asked to answer questions regarding clinical and personal experience with opioid use: chronicity of the injury/accident/problem prompting the clinic visit; whether they underwent surgery; whether they received pain medication prescription, opioid prescription, opioid disposal instructions, or naloxone prescription; whether they were currently using opioids at the time of response, and whether they personally knew someone who has been dependent or overdosed on opioids.

Study population

Seven percent of patients who opened the message (166 of 2352) completed the survey. Sixty-seven percent of the respondents (111 of 166) identified as female, 31% (52) identified as male, and 2% (3) preferred to not provide their gender (Table 1).
Table 1

Characteristics of 166 patients presenting to orthopaedic trauma surgery clinics

Patient characteristics
CharacteristicsNo. of respondents%a
Demographics
Gender
Female11167
Male5231
No answer31.8
Age (yrs)
18–2453.0
25–342817
35–441911
45–543320
55–644225
65–743219
75–8431.8
85+10.6
No answer21.2
Race/ethnicity
White13682
African American159.0
Asian31.8
Hispanic/Latino53.0
Other31.8
No answer42.4
Insurance status
Insured16298
Not insured21.2
No answer21.2
Highest education level
High school or less127.2
Some college148.4
2-year degree63.6
4-year degree4930
Graduate school or higher8249
No answer31.8
Employment status
Full-time8451
Part-time63.6
Unemployed1710
Retired3521
Disabled148.4
Student42.4
No answer31.8
Marital status
Married9658
Never married3420
Divorced2515
Widowed74.2
No answer42.4
ADI national quartile
16036
25131
32716
484.8
No answer2012
Clinical and personal experiences
Reason for visit
Acute injury/accident/problem < 2 weeks137.8
Subacute injury/accident/problem > 2 weeks9457
Chronic problem ≥ 1 year3420
No answer2515
Prior surgery
Yes15392
No127.2
No answer10.6
Prior pain prescription
Yes16499
No10.6
No answer10.6
Prior opioid prescription
Yes15694
No42.4
No answer63.6
Current opioid use
Yes1811
No13883
No answer106.0
Prior receipt of opioid disposal instructions
Yes53.0
No11770
No answer4427
Prior naloxone prescription
Yes169.6
No14084
No answer106.0
Know person—dependent
Self169.6
Family2716
Friend3521
Colleague21.2
Client/student/patient/etc.42.4
None8149
No answer10.6
Know person—overdose
Self21.2
Family127.2
Friend2716
Colleague31.8
Client/student/patient/etc.42.4
None11770
No answer10.6

ADI, Area deprivation index

aPercentages may not add to 100 from rounding error

Characteristics of 166 patients presenting to orthopaedic trauma surgery clinics ADI, Area deprivation index aPercentages may not add to 100 from rounding error Ninety-four percent of respondents (156) received prior opioid prescription, 10% (16) prior naloxone prescription, and 11% (18) were currently using an opioid. Fifty percent of respondents (84) reported personally knowing someone who has been dependent on opioids, with 19% (16 of 84) reporting self-dependency. Twenty-nine percent of respondents (48) reported knowing someone who had overdosed on opioids, with 4% (2 of 48) reporting self-overdose. Six percent of patients (10) reported knowing both (Table 1).

Primary and secondary outcomes

Our primary study outcome was to assess trauma patients’ understanding of opioid use. We defined understanding as correct identification and recognition of common opioids, suboxone/subutex, side effects, withdrawal symptoms, and appropriate disposal methods. Secondary outcomes were beliefs regarding time to dependency, safety of using over the counter (OTC) pain medications with opioids, comfort using naloxone, subjective pain level requiring opioid use, harmful effects of opioids, and confidence in their knowledge to safely manage opioid use. We also assessed addiction perception (whether others versus self can become addicted), with a discrepancy meaning they believe that others but not self can become addicted.

Statistical analysis

Survey data were analysed using descriptive statistics. Associations between demographics and clinical or personal experiences with variables assessing opioid understanding were explored using univariate and multivariable logistic regression (Additional file 1: Table S1, Table 3). The following potential confounders were included in the adjusted model: gender, age, race, marital status, employment status stratified by education level, ADI quartile, injury chronicity, prior opioid prescription, current opioid use, prior naloxone prescription, and knowing someone who has been dependent or addicted on opioids. Analyses were performed using Stata, version 16.0, software (StataCorp LLC, College Station, TX). Alpha was set at 0.05.
Table 3

Adjusted (multivariable) odds of orthopaedic trauma surgery patient understanding regarding opioid use

Parameter> 85% common opioidsSuboxone/subutex> 85% side effects> 85% withdrawal symptomsDependence < 2 weeksOTC x opioid safetyComfort with naloxoneAddiction discrepancyaKnow enough to take safely
Adjusted odds ratio (95% CI)
Gender
Maleb
Female0.68 (0.26–1.8)0.94 (0.37–2.4)1.7 (0.38–7.2)1.1 (0.44–2.7)2.0 (0.76–5.2)0.64 (0.22–1.8)1.7 (0.69–4.2)0.88 (0.25–3.1)1.8 (0.28–11)
Age
< 65 yearsb
≥ 65 years0.38 (0.11–1.3)0.42 (0.13–1.3)0.13 (0.01–1.3)0.63 (0.21–1.9)1.3 (0.45–4.0)0.77 (0.24–2.5)1.1 (0.40–3.0)1.2 (0.31–4.3)0.97 (0.11–9.0)
Race
Whiteb
Non-white0.50 (0.12–2.1)1.1 (0.28–3.9)1.5 (0.19–11)1.1 (0.29–4.2)0.45 (0.13–1.6)0.57 (0.15–2.1)1.0 (0.30–3.5)7.8 (1.9–31)**1.0
Marital status
Singleb
Married0.73 (0.30–1.8)2.0 (0.79–4.9)1.6 (0.40–6.2)1.8 (0.75–4.6)1.9 (0.79–4.8)0.81 (0.30–2.2)0.55 (0.24–1.2)1.1 (0.35–3.5)2.7 (0.41–17)
Employment status stratified by education level
Unemployedb

Employed w/

< 4-yr degree

1.1 (0.37–3.1)0.85 (0.30–2.4)0.67 (0.16–2.8)0.53 (0.19–1.5)0.53 (0.19–1.5)1.4 (0.46–4.1)1.5 (0.58–3.8)2.0 (0.55–7.1)0.53 (0.06–4.5)

Employed w/

≥ 4-yr degree

1.6 (0.55–4.6)1.6 (0.55–4.4)0.06 (0.006–0.56)*0.77 (0.28–2.2)0.28 (0.09–0.86)*0.75 (0.24–2.3)0.61 (0.22–1.7)0.73 (0.16–3.4)1.1 (0.07–17)
ADI national quartile
1b
20.79 (0.28–2.2)2.3 (0.86–6.4)8.8 (1.7–46)**2.7 (1.0–7.2)*1.2 (0.43–3.5)0.51 (0.18–1.5)1.1 (0.42–2.7)1.1 (0.32–4.1)0.13 (0.01–1.5)
3 + 40.66 (0.21–2.0)1.9 (0.62–5.6)6.1 (0.95–39)1.5 (0.49–4.4)1.1 (0.35–3.3)0.53 (0.16–1.8)0.65 (0.23–1.9)0.72 (0.15–3.4)0.41 (0.02–8.0)
Chronicity of injury
Acute or subacuteb
Chronic2.5 (0.79–8.0)1.3 (0.42–4.0)0.23 (0.03–1.6)0.51 (0.15–1.7)1.0 (0.31–3.4)0.49 (0.14–1.7)2.6 (0.89–7.9)2.7 (0.67–11)1.0
Prior opioid prescription
Nob
Yes1.01.01.01.01.01.01.01.01.0
Current opioid use
Nob
Yes1.9 (0.47–8.0)0.66 (0.15–2.9)1.9 (0.47–8.0)0.27 (0.05–1.6)0.61 (0.14–2.6)5.2 (1.0–27)*1.5 (0.35–6.2)0.97 (0.16–6.0)1.0
Prior naloxone prescription
Nob
Yes1.3 (0.31–5.2)1.3 (0.31–5.1)1.3 (0.31–5.2)0.73 (0.16–3.3)0.90 (0.23–3.5)1.8 (0.42–7.9)1.8 (0.48–6.9)0.82 (0.13–5.2)1.0
Know someone dependent/overdosed
Nob
Yes1.9 (0.74–5.0)2.2 (0.88–5.7)1.9 (0.74–5.0)2.6 (1.1–6.5)*3.8 (1.5–9.8)**0.78 (0.29–2.1)1.5 (0.66–3.5)0.24 (0.07–0.76)*1.8 (0.26–12)

Bold values indicate significant associations between patient characteristics and measures of understanding regarding opioid use

OTC, Over the counter; ADI, area deprivation index

*Significant at p < 0.05

**Significant at p < 0.01

***Significant at p < 0.001

aAddiction discrepancy = patients who believed that others, but not self, can become addicted to opioids

bReferent

Results

Current level of patient understanding regarding opioid use

Excellent recognition was defined as > 85%, poor as < 55% items identified correctly. Twenty-nine percent of patients (48 of 166) demonstrated excellent recognition of common opioids. Ten percent (17) had excellent recognition of side effects, 30% (50) withdrawal symptoms, and 2.4% (4) appropriate disposal methods. While 11% of patients (18) had poor recognition of common opioids, 56% (93), 33% (54), and 52% (86) poorly recognized side effects, withdrawal symptoms, and disposal methods, respectively (Fig. 1). Further, 34% (56) believed dependence takes weeks to months to develop, and 18% (30) were uncomfortable using naloxone. While patients almost unanimously understood that opioids are harmful and that others can become addicted, 11% (19) had a discrepancy in addiction perception. Almost all patients (88%) stated that they would only take an opioid for moderate to severe pain, defined as a score ≥ 5/10 on the visual analog scale. Eighty-six percent of patients (143) believed they currently know enough to take opioids safely (Table 2).
Fig. 1

Common opioids, side effects, withdrawal symptoms, and disposal methods identified correctly by orthopaedic trauma patients

Table 2

Understanding regarding opioid use of 166 patients presenting to orthopaedic trauma surgery clinics

Patient understanding regarding opioid use
ResponsesNo. of respondents%a
1. Identification of opioids
85%+ correct4829
70–84%6237
55–69%3823
< 55%1811
No answer00.0
2. Identification of suboxone/subutex
Both2414
One2616
Neither11670
No answer00.0
3. Identification of side effects
85%+ correct1710
70–84%1811
55–69%3521
< 55%9356
No answer31.8
4. Identification of withdrawal symptoms
85%+ correct5030
70–84%3219
55–69%2515
< 55%5433
No answer53.0
5. Identification of appropriate disposal methods
85%+ correct42.4
70–84%127.2
55–69%6439
< 55%8652
No answer00.0
6. Time to dependence
< 1 week6137
1–2 weeks3521
2 weeks–1 month2817
> 1 month2817
No answer148.4
7. Safety of using OTC pain medication x opioids
Yes5936
No6036
No answer4728
8. Comfort level with using naloxone
Extremely comfortable4024
Somewhat comfortable2616
Neutral6841
Somewhat uncomfortable1710
Extremely uncomfortable137.8
No answer21.2
9. Pain level (1–10) requiring opioid use
0–200.0
3–431.8
5–61911
7–87545
9–105332
No answer169.6
10. I can become addicted to opioids
Yes14084
No1911
No answer74.2
11. Others can become addicted to opioids
Yes16599
No00.0
No answer10.6
12. Opioids can harm me
Yes15996
No53.0
No answer21.2
13. I know enough to take opioids safely
Yes14386
No116.6
No answer127.2

OTC, Over the counter

aPercentages may not add to 100 from rounding error

Common opioids, side effects, withdrawal symptoms, and disposal methods identified correctly by orthopaedic trauma patients Understanding regarding opioid use of 166 patients presenting to orthopaedic trauma surgery clinics OTC, Over the counter aPercentages may not add to 100 from rounding error

Demographics associated with level of understanding

Compared with white patients, non-white patients had 7.8 times greater odds (95% confidence interval [CI] 1.9–31) of signifying a discrepancy in addiction perception (p = 0.004). Employment status stratified by education level was also independently associated with knowledge of side effects. Employed patients with the highest education level were less knowledgeable about side effects (adjusted odds ratio [aOR] 0.06, 95% CI 0.006–0.56; p = 0.01) and less likely to understand that dependence can occur within 2 weeks of beginning opioids (aOR 0.28, 95% CI 0.09–0.86; p = 0.03) than patients who were unemployed. After adjusting for potential confounders, patients in the second least disadvantaged ADI quartile were more knowledgeable about side effects (aOR 8.8, 95% CI 1.7–46) and withdrawal symptoms (aOR 2.7, 95% CI 1.0–7.2; p = 0.046) than those in the least disadvantaged quartile. No other demographics were significantly associated with level of patient understanding (Table 3). Adjusted (multivariable) odds of orthopaedic trauma surgery patient understanding regarding opioid use Employed w/ < 4-yr degree Employed w/ ≥ 4-yr degree Bold values indicate significant associations between patient characteristics and measures of understanding regarding opioid use OTC, Over the counter; ADI, area deprivation index *Significant at p < 0.05 **Significant at p < 0.01 ***Significant at p < 0.001 aAddiction discrepancy = patients who believed that others, but not self, can become addicted to opioids bReferent

Clinical and personal experiences associated with level of understanding

Patients currently using opioids had 5.2 times greater odds (95% CI 1.0–27) of understanding that it is safe to take opioids with OTC pain medications (p = 0.046). Patients who knew someone who was dependent or overdosed on opioids were significantly less likely to believe that others but not self can become addicted (aOR 0.24, 95% CI 0.07–0.76; p = 0.02). They also possessed greater knowledge regarding withdrawal symptoms (aOR 2.6, 95% CI 1.1–6.5, p = 0.03) and were more likely to understand that dependence can develop within 2 weeks of initiating opioids (aOR 3.8, 95% CI 1.5–9.8, p = 0.005). No other clinical or personal experiences were significantly associated with level of patient understanding (Table 3).

Discussion

The safe prescribing of opioids is a critical issue in medicine and especially for orthopaedic trauma surgery. It is crucial to understand and improve the level of patient understanding regarding the use of opioids to improve our care of patients. Our study illustrates that there are significant gaps in understanding and concerning patterns of beliefs regarding opioid use for orthopaedic trauma surgery patients, even amongst a predominantly high socioeconomic status population. While our respondents had a fairly strong recognition of common opioids, they had a poor understanding of side effects, withdrawal symptoms, and appropriate disposal methods. One potential explanation may be that commercial media has improved public recognition of common opioids, but awareness of their medical implications is still lacking [24, 25] This theory is further supported by our results illustrating greater identification of side effects, such as addiction (87%) and constipation (78%), that have received more media attention [26]. Our study demonstrates the need for additional education of all our patients in several areas. A subset of the respondents believe that they cannot become addicted to opioids, even when they recognize the addictive potential for others. This is consistent with the results of previous studies, which have shown inaccurate perception of individual risk may be due to addiction stigma or the perception that addiction is a moral failing that can be resisted through personal willpower [27-29]. Patients also lacked knowledge about the rapid nature of opioid dependence and naloxone use [30, 31]. Patients had a better understanding of dependence and appropriate dosing, as over half of our patients understand that dependence can occur within 2 weeks and patients almost universally would not take an opioid for mild pain levels. This may demonstrate early successes with patient education on opioid use. We found that race was independently associated with level of understanding, with patients identifying as white being significantly less likely to have discrepancy in addiction perception [32, 33]. This may be attributed to an awareness that the most dramatic increase in overdose mortality in the last two decades occurred amongst non-Hispanic whites [34, 35]. Much of the recent social and political attention on the opioid epidemic has also been focused on this population [36, 37]. While use amongst whites has been framed as a public health crisis, the media has traditionally portrayed blacks with opioid use disorders as having a moral shortcoming and undergoing greater criminalization [36]. Minorities thus may have alternative perceptions regarding opioid use and self-addiction. However, our findings cannot be confidently interpreted without more robust quantitative studies that do not use race as a surrogate for other factors (i.e., health behaviours). We further illustrated that employment with higher education level and being from the least disadvantaged ADI quartile were associated with lesser levels of knowledge regarding opioid use when controlling for potential confounders. This contrasts with the results of Bargon et al. [20], who demonstrated higher education to be associated with patients understanding the importance of opioid prescribing policies, suggesting greater knowledge of opioid misuse. This conflicting and limited evidence emphasizes the necessity for further studies evaluating patient knowledge of opioids in orthopaedic surgery. Our findings may reflect that patients of lower socioeconomic measures and from more disadvantaged geographic regions are more frequently exposed to opioid prescription, chronic consumption, and related overdose in their communities [38-41]. This exposure, in turn, may translate to greater knowledge regarding opioids. In addition, patients had significantly greater levels of understanding if they were currently using opioids or knew someone who misused opioids. This aligns with the results of Razdan et al., who determined that knowledge regarding opioid use for paediatric patients was greater for parents who knew someone who had become addicted to opioids [42]. Stover et al. [43] also demonstrated that young adults who received prior naloxone training or opioid prescriptions scored significantly higher on the Opioid Overdose Knowledge Scale. It is possible that these patients were educated by their prescribing physician or distributing pharmacist on the appropriate use and risks involved. Another plausible explanation is that in light of the ongoing opioid epidemic, patients were more aware of the intrinsic risks and more inclined to research these risks upon receiving prescriptions or having someone they know become dependent or overdosing on opioids [43]. Recent initiatives to educate patients through counseling and public materials thus may be effective, and it is important for surgeons to follow recommendations for co-prescription of naloxone and opioids. Altogether, these results suggest that clinical and personal experience with opioids should be emphasized when taking patient histories, and those with positive histories may be more knowledgeable in the appropriate use and risks of taking prescription opioids in the postoperative period. Our study is not without limitations. The electronic format of our survey distribution was a result of the COVID-19 pandemic, which restricted access to patient care areas (i.e. trauma clinics). Subsequently, the study was limited by responder bias with the low response rate. Responders likely differ from non-responders, especially since the survey’s electronic format tends to attract more white responders possessing higher socioeconomic measures [44, 45]. As a result, the respondents did not accurately represent the trauma patient population seen by our institution, which serves a clinically diverse, minority-majority patient population within an urban environment. However, it must be noted that the response rate was based on the 2352 patients who opened the survey invitation, thereby controlling for internet access and associated socioeconomics to an extent. Respondents also likely had more personal experiences with opioids which motivated them to answer the survey. Despite the high socioeconomic measures of our cohort, we were able to capture 17 unique individuals (10%) who reported self-dependency or overdose on opioids, which is higher than the estimated national rate of prescription opioid misuse (3.6%) amongst people aged 12 years or older [46]. Overall, our respondent characteristics would trend toward greater awareness of opioids and the importance of understanding their appropriate use [20, 43], so the low level of understanding in our results likely overestimates opioid knowledge, emphasizing the importance of presenting our findings.

Conclusions

In conclusion, all prescribers should be aware that there is a low level of understanding regarding opioid use in patients who present to orthopaedic trauma surgery clinics. This places patients at higher risk for misusing opioids if prescribed. It is essential to emphasize that providers should not exacerbate existing prescribing disparities and reduce access to opioids for patients with lesser understanding. Rather, more involved educational interventions should be taken with these patients to mediate risk for misuse, and improvements in overall patient education should be established at all institutions. To more comprehensively study patient understanding, future studies should apply larger scale, multidisciplinary, multicenter surveys and investigate the effectiveness of specific educational interventions in improving patient knowledge. Application of robust qualitative methods grounded in well-established social theories, like the Health Belief Model, which is outside the scope of this study, would be better able to provide reasons behind the perceptions assessed here as well.
  39 in total

1.  An Educational Intervention Decreases Opioid Prescribing After General Surgical Operations.

Authors:  Maureen V Hill; Ryland S Stucke; Michelle L McMahon; Julia L Beeman; Richard J Barth
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2.  The War on Drugs That Wasn't: Wasted Whiteness, "Dirty Doctors," and Race in Media Coverage of Prescription Opioid Misuse.

Authors:  Julie Netherland; Helena B Hansen
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3.  Knowledge of Opioid Overdose and Attitudes to Supply of Take-Home Naloxone Among People with Chronic Noncancer Pain Prescribed Opioids.

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Journal:  Pain Med       Date:  2018-03-01       Impact factor: 3.750

4.  Surgery program directors' knowledge of opioid prescribing regulations: a survey study.

Authors:  Brian K Yorkgitis; Desiree Raygor; Elizabeth Bryant; Gabriel Brat; Douglas S Smink; Marie Crandall
Journal:  J Surg Res       Date:  2018-03-20       Impact factor: 2.192

5.  Opioid Addiction Stigma: The Intersection of Race, Social Class, and Gender.

Authors:  Emily Wood; Marta Elliott
Journal:  Subst Use Misuse       Date:  2019-12-23       Impact factor: 2.164

6.  A comparison of a postal survey and mixed-mode survey using a questionnaire on patients' experiences with breast care.

Authors:  Marloes Zuidgeest; Michelle Hendriks; Laura Koopman; Peter Spreeuwenberg; Jany Rademakers
Journal:  J Med Internet Res       Date:  2011-09-27       Impact factor: 5.428

7.  Patients' perception about opioids and addiction in South Korea.

Authors:  Cho Long Kim; Sung Jun Hong; Yun Hee Lim; Jae Hun Jeong; Ho Sik Moon; Hey Ran Choi; Sun Kyung Park; Jung Eun Kim; Hakjong You; Jae Hun Kim
Journal:  Korean J Pain       Date:  2020-07-01

8.  Characteristics of physicians who prescribe opioids for chronic pain: a meta-narrative systematic review.

Authors:  W Michael Hooten; Jodie Dvorkin; Nafisseh S Warner; Amy Cs Pearson; M Hassan Murad; David O Warner
Journal:  J Pain Res       Date:  2019-07-24       Impact factor: 3.133

9.  Prescription opioid use and misuse among adolescents and young adults in the United States: A national survey study.

Authors:  Joel D Hudgins; John J Porter; Michael C Monuteaux; Florence T Bourgeois
Journal:  PLoS Med       Date:  2019-11-05       Impact factor: 11.069

10.  Rates and risk factors for prolonged opioid use after major surgery: population based cohort study.

Authors:  Hance Clarke; Neilesh Soneji; Dennis T Ko; Lingsong Yun; Duminda N Wijeysundera
Journal:  BMJ       Date:  2014-02-11
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