Literature DB >> 3495220

On a prezygotic origin of normal/balanced translocation mosaics.

J M Cantú, C Ruiz.   

Abstract

Based on a theoretical model for the production of some structural mosaicisms, the authors propose a mechanism for the origin of normal/balanced translocation mosaics. Single strand breaks and nonhomologous hemichromatid joining are implicated and, when applied to homologous chromosomes, could explain some instances of nondisjunction independent of centromere function.

Mesh：

Year:  1986        PMID： 3495220

Source DB:  PubMed          Journal:  Ann Genet        ISSN： 0003-3995


  3 in total

1.  On the variable effect of mosaic normal/balanced chromosomal rearrangements in man.

Authors:  A Kleczkowska; J P Fryns; H Van den Berghe
Journal:  J Med Genet       Date:  1990-08       Impact factor: 6.318

2.  Mosaicism with a normal cell line and an autosomal structural rearrangement.

Authors:  R J Gardner; H E Dockery; P H Fitzgerald; R G Parfitt; D R Romain; N Scobie; R L Shaw; P Tumewu; A J Watt
Journal:  J Med Genet       Date:  1994-02       Impact factor: 6.318

Review 3.  Somatic/gonadal mosaicism for structural autosomal rearrangements: female predominance among carriers of gonadal mosaicism for unbalanced rearrangements.

Authors:  Natalia V Kovaleva; Philip D Cotter
Journal:  Mol Cytogenet       Date:  2016-01-28       Impact factor: 2.009
  3 in total

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