Literature DB >> 3494949

Acid-dependent ligand dissociation and recycling of LDL receptor mediated by growth factor homology region.

C G Davis, J L Goldstein, T C Südhof, R G Anderson, D W Russell, M S Brown.   

Abstract

A domain in the low-density lipoprotein receptor contains three cysteine-rich 'growth factor' repeats like those that occur in many proteins. When this domain is deleted, the receptor no longer releases its ligand at acid pH, it is no longer recycled efficiently and it is rapidly degraded after ligand binding.

Entities:  

Mesh：

Substances：

Year:  1987        PMID： 3494949     DOI： 10.1038/326760a0

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  111 in total

1.  Role of an intramolecular contact on lipoprotein uptake by the LDL receptor.

Authors:  Zhenze Zhao; Peter Michaely
Journal:  Biochim Biophys Acta       Date:  2011-04-09

2.  Sequence and structure of human rhinoviruses reveal the basis of receptor discrimination.

Authors:  Marketa Vlasak; Soile Blomqvist; Tapani Hovi; Elizabeth Hewat; Dieter Blaas
Journal:  J Virol       Date:  2003-06       Impact factor: 5.103

3.  Molecular basis of loss-of-function mutations in the glp-1 gene of Caenorhabditis elegans.

Authors:  V Kodoyianni; E M Maine; J Kimble
Journal:  Mol Biol Cell       Date:  1992-11       Impact factor: 4.138

Review 4.  Low-density lipoprotein receptor family: endocytosis and signal transduction.

Authors:  Y Li; J Cam; G Bu
Journal:  Mol Neurobiol       Date:  2001-02       Impact factor: 5.590

5.  K Domain CR9 of Low Density Lipoprotein (LDL) Receptor-related Protein 1 (LRP1) Is Critical for Aggregated LDL-induced Foam Cell Formation from Human Vascular Smooth Muscle Cells.

Authors:  Paula Costales; Pablo Fuentes-Prior; Jose Castellano; Elena Revuelta-Lopez; Maria Ángeles Corral-Rodríguez; Laura Nasarre; Lina Badimon; Vicenta Llorente-Cortes
Journal:  J Biol Chem       Date:  2015-04-27       Impact factor: 5.157

6.  The cloning, characterization, and expression profiling of the LRP8 gene in duck (Anas platyrhynchos).

Authors:  Shenqiang Hu; Hehe Liu; Zhixiong Pan; Fang Ding; Jie Kou; Liang Li; Jiwen Wang
Journal:  Mol Cell Biochem       Date:  2012-12-07       Impact factor: 3.396

7.  Fates of endocytosed somatostatin sst2 receptors and associated agonists.

Authors:  J A Koenig; R Kaur; I Dodgeon; J M Edwardson; P P Humphrey
Journal:  Biochem J       Date:  1998-12-01       Impact factor: 3.857

8.  The LDL receptor and LRP are receptors for beta VLDL on pigeon monocyte-derived macrophages.

Authors:  N L Jones; M Gupta; J C Lewis
Journal:  Virchows Arch       Date:  1995       Impact factor: 4.064

9.  Human homologue of mouse lymph node homing receptor: evolutionary conservation at tandem cell interaction domains.

Authors:  M H Siegelman; I L Weissman
Journal:  Proc Natl Acad Sci U S A       Date:  1989-07       Impact factor: 11.205

10.  A proprotein convertase subtilisin/kexin type 9 neutralizing antibody reduces serum cholesterol in mice and nonhuman primates.

Authors:  Joyce C Y Chan; Derek E Piper; Qiong Cao; Dongming Liu; Chadwick King; Wei Wang; Jie Tang; Qiang Liu; Jared Higbee; Zhen Xia; Yongmei Di; Susan Shetterly; Ziva Arimura; Heather Salomonis; William G Romanow; Stephen T Thibault; Richard Zhang; Ping Cao; Xiao-Ping Yang; Timothy Yu; Mei Lu; Marc W Retter; Gayle Kwon; Kirk Henne; Oscar Pan; Mei-Mei Tsai; Bryna Fuchslocher; Evelyn Yang; Lei Zhou; Ki Jeong Lee; Mark Daris; Jackie Sheng; Yan Wang; Wenyan D Shen; Wen-Chen Yeh; Maurice Emery; Nigel P C Walker; Bei Shan; Margrit Schwarz; Simon M Jackson
Journal:  Proc Natl Acad Sci U S A       Date:  2009-05-14       Impact factor: 11.205
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.