Literature DB >> 3494130

Effect of tamoxifen on pokeweed mitogen stimulated immunoglobulin secretion in vitro.

E Baral, H Blomgren, J Wasserman, S Rotstein, L V von Stedingk.   

Abstract

The influence of Tamoxifen on pokeweed mitogen induced immunoglobulin (Ig) secretion of human blood lymphocytes was tested in vitro. It was observed that pretreatment of T cell enriched preparations with "therapeutic" concentrations of Tamoxifen augmented their capacity to promote IgG but not IgM secretion of untreated autologous B-lymphocytes. Cultures containing Tamoxifen pretreated B cell enriched preparations and untreated T cells exhibited reduced secretion of both IgG and IgM.

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Year:  1986        PMID: 3494130

Source DB:  PubMed          Journal:  J Clin Lab Immunol        ISSN: 0141-2760


  2 in total

Review 1.  Understanding sex biases in immunity: effects of estrogen on the differentiation and function of antigen-presenting cells.

Authors:  Greg Nalbandian; Susan Kovats
Journal:  Immunol Res       Date:  2005       Impact factor: 2.829

2.  Fatty acid modulation of antiestrogen action and antiestrogen-binding protein in cultured lymphoid cells.

Authors:  Y K Hoh; E H Lim; S O Ooi; O L Kon
Journal:  Experientia       Date:  1990-10-15
  2 in total

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