Influence of genetic variants of opioid-related genes on opioid-induced adverse effects in patients with lung cancer: A STROBE-compliant observational study: Erratum.

In the article, “Influence of genetic variants of opioid-related genes on opioid-induced adverse effects in patients with lung cancer: A STROBE-compliant observational study”[ which published in Volume 100, Issue 44 of Medicine¸ the values in the OR column of Table 2 were rounded. The correct table appears below and have been corrected in the published article.

Insert Table 2

	rs1799971 Alt allele freq: 0.494 A > G ORRM1										rs2234918 Alt allele freq: 0.79 C > T OPRD1
Allele	A/A	A/G + G/G	OR	95% CI	P	G/G	A/A + A/G	OR	95% CI	P	C/C	C/T + T/T	OR	95% CI	P	T/T	C/C + C/T	OR	95% CI	P
	n = 22	n = 66				n = 21	n = 67				n = 5	n = 83				n = 56	n = 32
Somnolence	6 (27.3%)	13 (19.7%)	1.5	0.5 to 4.7	.55∗	0 (0.0%)	19 (28.4%)	0	0 to 0.6	.005∗	1 (20.0%)	18 (21.7%)	0.9	0.1 to 8.6	1.00∗	10 (17.9%)	9 (28.1%)	0.6	0.2 to 1.6	.29∗
Nausea	1 (4.5%)	13 (19.7%)	0.2	0.02 to 1.6	.17∗	5 (23.8%)	9 (13.4%)	2.0	0.6 to 6.9	.31∗	0 (0.0%)	14 (16.9%)	0	0 to 6.0	1.00∗	12 (21.4%)	2 (6.3%)	4.1	0.9 to 19.6	.07∗
Constipation	10 (45.5%)	24 (36.4%)	1.5	0.6 to 3.9	.46∗	9 (42.9%)	25 (37.3%)	1.3	0.5 to 3.4	.49∗	1 (20.0%)	33 (39.8%)	0.4	0.04 to 3.5	.64∗	23 (41.1%)	11 (34.4%)	1.3	0.5 to 3.3	.65∗
Delirium	1 (4.5%)	9 (13.6%)	0.3	0.04 to 2.5	.44∗	3 (14.2%)	7 (10.4%)	1.4	0.3 to 6.1	.70∗	0 (0.0%)	10 (12.0%)	0	0 to 9.2	1.00∗	6 (10.7%)	4 (12.5%)	0.8	0.2 to 3.2	1.00∗
Urinary retention	0 (0.0%)	3 (4.5%)	0	0 to 7.6	1.00∗	2 (9.5%)	1 (1.5%)	7.0	0.6 to 80.8	.14∗	0 (0.0%)	3 (3.6%)	0	0 to 46.4	1.00∗	2 (3.6%)	1 (3.1%)	1.2	0.1 to 13.2	1.00∗
Pruritus	4 (18.1%)	8 (12.1%)	1.6	0.5 to 6.0	.49∗	2 (9.5%)	10 (14.9%)	0.6	0.1 to 3.00	.72∗	0 (0.0%)	12 (14.5%)	0	0 to 7.3	1.00∗	8 (14.3%)	4 (12.5%)	1.2	0.3 to 4.2	1.00∗

Fisher's exact test

ABCB1 = Adenosine Triphosphate Binding Cassette B1, CI = Confidence Interval, COMT = Catechol-O-Methyltransferase, DRD2 = Dopamine Receptor D2, FAAH = Fatty Acid Amide Hydrolase, GIRK2 = G-protein regulated Inward Rectifier potassium channel 2, OPRD1 = Opioid δ receptor 1, OPRK1 = Opioid κ Receptor 1, OPRM1 = Opioid μ Receptor 1, OR = Odds Ratio