Hanna Faber1,2, Philipp Berens3,4, Jens Martin Rohrbach5. 1. Universitäts-Augenklinik Tübingen, Universitätsklinikum Tübingen, Tübingen, Deutschland. hanna.faber@med.uni-tuebingen.de. 2. Department für Augenheilkunde, Universitätsklinikum Tübingen, Tübingen, Deutschland, Elfriede-Aulhorn-Str. 7, 72076. hanna.faber@med.uni-tuebingen.de. 3. Department für Augenheilkunde, Universitätsklinikum Tübingen, Tübingen, Deutschland, Elfriede-Aulhorn-Str. 7, 72076. 4. Tübingen AI Center, Tübingen, Deutschland. 5. Universitäts-Augenklinik Tübingen, Universitätsklinikum Tübingen, Tübingen, Deutschland.
Abstract
BACKGROUND: According to the WHO Malaria Report 2019 a total of 229 million people fall ill with malaria each year and two thirds of deaths involve children under 5 years of age. AIM: To review the fundus changes in the context of malaria and the importance of ophthalmoscopy in the diagnosis. MATERIAL AND METHODS: Summary of changes in cerebral malaria visible on fundus examination, possible underlying pathomechanisms and the value of ophthalmoscopy in practice. RESULTS: Retinal findings in malaria include white or gray staining of the retina (retinal whitening), color change of retinal vessels (orange or white staining), hemorrhages often with a white center, such as Roth's spot and papilledema. DISCUSSION: The retinal changes in malaria are specific and may help to differentiate malaria from other causes of coma and fever. Smartphone-based fundus photography and artificial intelligence could support malaria diagnostics particularly in resource-poor regions.
BACKGROUND: According to the WHO Malaria Report 2019 a total of 229 million people fall ill with malaria each year and two thirds of deaths involve children under 5 years of age. AIM: To review the fundus changes in the context of malaria and the importance of ophthalmoscopy in the diagnosis. MATERIAL AND METHODS: Summary of changes in cerebral malaria visible on fundus examination, possible underlying pathomechanisms and the value of ophthalmoscopy in practice. RESULTS: Retinal findings in malaria include white or gray staining of the retina (retinal whitening), color change of retinal vessels (orange or white staining), hemorrhages often with a white center, such as Roth's spot and papilledema. DISCUSSION: The retinal changes in malaria are specific and may help to differentiate malaria from other causes of coma and fever. Smartphone-based fundus photography and artificial intelligence could support malaria diagnostics particularly in resource-poor regions.
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