| Literature DB >> 34939221 |
Nicolaas I Bohnen1, Rui M Costa2, William T Dauer3, Stewart A Factor4, Nir Giladi5, Mark Hallett6, Simon J G Lewis7, Alice Nieuwboer8, John G Nutt9, Kaoru Takakusaki10, Un Jung Kang11, Serge Przedborski12, Stella M Papa13.
Abstract
Gait and balance abnormalities develop commonly in Parkinson's disease and are among the motor symptoms most disabling and refractory to dopaminergic or other treatments, including deep brain stimulation. Efforts to develop effective therapies are challenged by limited understanding of these complex disorders. There is a major need for novel and appropriately targeted research to expedite progress in this area. The Scientific Issues Committee of the International Parkinson and Movement Disorder Society has charged a panel of experts in the field to consider the current knowledge gaps and determine the research routes with highest potential to generate groundbreaking data.Entities:
Keywords: FOG; Parkinson's disease; balance; freezing; gait; research priorities
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Year: 2021 PMID: 34939221 DOI: 10.1002/mds.28883
Source DB: PubMed Journal: Mov Disord ISSN: 0885-3185 Impact factor: 9.698