Literature DB >> 34938691

A Higher Altitude Is Associated with Increased Incidence of Infections following Primary Total Hip Arthroplasty.

Nabil Z Khan1, Stefan N Hamaway1, Miriam D Weisberg1, Andrew R Horn1, Rushabh M Vakharia1, Afshin E Razi1.   

Abstract

PURPOSE: The purpose of this study was to evaluate whether patients undergoing primary total hip arthroplasty (THA) at a higher elevation have higher rates of: 1) in-hospital length of stay (LOS); 2) surgical site infections (SSIs); 3) periprosthetic joint infections (PJIs); and 4) costs.
MATERIALS AND METHODS: The Medicare claims database was used to identify patients who underwent primary THA at an altitude higher than 4,000 feet (ft). High-altitude patients were matched to patients who underwent primary THA at an altitude less than 100 ft, yielding 24,958 and 124,765 patients respectively. Outcomes that were assessed included in-hospital LOS, SSIs, PJIs, and costs of care. A P-value less than 0.001 was considered statistically significant.
RESULTS: Patients in the study group had significantly longer in-hospital LOS (4 days vs 3 days, P<0.0001). In addition, patients in the study group had a significantly higher incidence and odds of developing SSIs (1.16% vs 0.86%; odds ratio [OR], 1.34; P<0.0001) and PJIs (0.91% vs 0.58%; OR, 1.56; P<0.0001) within 90-days following the index procedure, compared to matched controls. Higher altitude patients incurred higher day of surgery ($16,139.76 vs $15,279.42; P<0.0001) and 90-day costs ($18,647.51 vs $16,401.62; P<0.0001).
CONCLUSION: This study demonstrated that primary THA procedures performed at an elevation higher than 4,000 ft are associated with longer in-hospital LOS, higher rates of SSIs, PJIs, and costs of care. Orthopedists and other healthcare professionals can use this information to provide adequate education for these patients regarding the potential complications that may occur following their procedure.
Copyright © 2021 by Korean Hip Society.

Entities:  

Keywords:  Altitude; Costs; Database; Medicare; Total hip arthroplasty

Year:  2021        PMID: 34938691      PMCID: PMC8654588          DOI: 10.5371/hp.2021.33.4.219

Source DB:  PubMed          Journal:  Hip Pelvis        ISSN: 2287-3260


  18 in total

Review 1.  Climate, altitude, and blood pressure.

Authors:  J M Hanna
Journal:  Hum Biol       Date:  1999-08       Impact factor: 0.553

Review 2.  Infectious Diseases at High Altitude.

Authors:  Buddha Basnyat; Jennifer M Starling
Journal:  Microbiol Spectr       Date:  2015-08

3.  Association of Hospital Altitude and Postoperative Infectious Complications After Major Operations.

Authors:  Davis M Aasen; Cole Wiedel; Paul Maroni; Mark E Cohen; Xiangju Meng; Robert A Meguid
Journal:  High Alt Med Biol       Date:  2019-10-16       Impact factor: 1.981

4.  Clinical Impact and Economic Burden of Hospital-Acquired Conditions Following Common Surgical Procedures.

Authors:  Samantha R Horn; Tiffany C Liu; Jason A Horowitz; Cheongeun Oh; Cole A Bortz; Frank A Segreto; Dennis Vasquez-Montes; Leah M Steinmetz; Chloe Deflorimonte; Shaleen Vira; Bassel G Diebo; Brian J Neuman; Micheal Raad; Daniel M Sciubba; Renaud Lafage; Virginie Lafage; Hamid Hassanzadeh; Peter G Passias
Journal:  Spine (Phila Pa 1976)       Date:  2018-11-15       Impact factor: 3.468

5.  Predictors of increased cost and length of stay in the treatment of postoperative spine surgical site infection.

Authors:  Todd J Blumberg; Erik Woelber; Carlo Bellabarba; Richard Bransford; Nicholas Spina
Journal:  Spine J       Date:  2017-07-21       Impact factor: 4.166

6.  Association of Hospital Participation in a Medicare Bundled Payment Program With Volume and Case Mix of Lower Extremity Joint Replacement Episodes.

Authors:  Amol S Navathe; Joshua M Liao; Sarah E Dykstra; Erkuan Wang; Zoe M Lyon; Yash Shah; Joseph Martinez; Dylan S Small; Rachel M Werner; Claire Dinh; Xinshuo Ma; Ezekiel J Emanuel
Journal:  JAMA       Date:  2018-09-04       Impact factor: 56.272

7.  The impact of surgical-site infections following orthopedic surgery at a community hospital and a university hospital: adverse quality of life, excess length of stay, and extra cost.

Authors:  James D Whitehouse; N Deborah Friedman; Kathryn B Kirkland; William J Richardson; Daniel J Sexton
Journal:  Infect Control Hosp Epidemiol       Date:  2002-04       Impact factor: 3.254

8.  2018 John Charnley Award: Analysis of US Hip Replacement Bundled Payments: Physician-initiated Episodes Outperform Hospital-initiated Episodes.

Authors:  William S Murphy; Ahmed Siddiqi; Tony Cheng; Ben Lin; David Terry; Carl T Talmo; Stephen B Murphy
Journal:  Clin Orthop Relat Res       Date:  2019-02       Impact factor: 4.176

9.  High Altitude Is an Independent Risk Factor for Developing a Pulmonary Embolism, but Not a Deep Vein Thrombosis Following a 1- to 2-Level Lumbar Fusion.

Authors:  Chester J Donnally; Ajit M Vakharia; Jonathan I Sheu; Rushabh M Vakharia; Dhanur Damodar; Kartik Shenoy; Joseph P Gjolaj
Journal:  Global Spine J       Date:  2019-02-26

10.  A higher altitude is an independent risk factor for venous thromboembolisms following total shoulder arthroplasty.

Authors:  Dhanur Damodar; Rushabh Vakharia; Ajit Vakharia; Jon Sheu; Chester J Donnally; Jonathan C Levy; Lee Kaplan; Julianne Munoz
Journal:  J Orthop       Date:  2018-10-08
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