Literature DB >> 3493289

Species-specificity of T cell stimulating activities of IL 2 and BSF-1 (IL 4): comparison of normal and recombinant, mouse and human IL 2 and BSF-1 (IL 4).

T R Mosmann, T Yokota, R Kastelein, S M Zurawski, N Arai, Y Takebe.   

Abstract

Mouse and human interleukin 2 (IL 2) both cause proliferation of T cells of the homologous species at high efficiency. Human IL 2 also stimulates proliferation of mouse T cells at similar concentrations, whereas mouse IL 2 stimulates human T cells at a lower (sixfold to 170-fold) efficiency. In contrast, the T cell stimulating activities of mouse and human B cell stimulatory factor 1 (interleukin 4; IL 4) appear to be species specific over the range of concentrations tested; we detected no activity of mouse IL 4 on human T cells, or human IL 4 on mouse T cells.

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Year:  1987        PMID： 3493289

Source DB:  PubMed          Journal:  J Immunol        ISSN： 0022-1767            Impact factor:   5.422


  54 in total

Review 1.  Human lymphohematopoietic reconstitution and immune function in immunodeficient mice receiving cotransplantation of human thymic tissue and CD34(+) cells.

Authors:  Zheng Hu; Yong-Guang Yang
Journal:  Cell Mol Immunol       Date:  2012-02-06       Impact factor: 11.530

2.  Human and murine IL2 receptors differentially respond to the human-IL2 component of immunocytokines.

Authors:  Zulmarie Perez Horta; Swetha Saseedhar; Alexander L Rakhmilevich; Lakeesha Carmichael; Jacquelyn A Hank; Margaret Boyden; Stephen D Gillies; Paul M Sondel
Journal:  Oncoimmunology       Date:  2018-05-07       Impact factor: 8.110

3.  Interleukin-2-mediated inhibition of dendritic cell development correlates with decreased CD135 expression and increased monocyte/macrophage precursors.

Authors:  Alan D Guerrero; Matthew B Dong; Yongge Zhao; Annie Lau-Kilby; Kristin V Tarbell
Journal:  Immunology       Date:  2014-12       Impact factor: 7.397

Review 4.  Interleukin-4. A regulatory protein.

Authors:  J H Jansen; W E Fibbe; R Willemze; J C Kluin-Nelemans
Journal:  Blut       Date:  1990-05

5.  Cross-linking of interleukin 4 to surface molecules on murine T and B lymphocytes.

Authors:  R Fernandez-Botran; J W Uhr; E S Vitetta
Journal:  Proc Natl Acad Sci U S A       Date:  1989-06       Impact factor: 11.205

6.  Analysis of adhesion molecules, target cells, and role of IL-2 in human FOXP3+ regulatory T cell suppressor function.

Authors:  Dat Q Tran; Deborah D Glass; Gulbu Uzel; Dirk A Darnell; Christine Spalding; Steven M Holland; Ethan M Shevach
Journal:  J Immunol       Date:  2009-03-01       Impact factor: 5.422

7.  Enumeration of viral antigen-reactive helper T lymphocytes in human peripheral blood by limiting dilution for analysis of viral antigen-reactive T-cell pools in virus-seropositive and virus-seronegative individuals.

Authors:  K A Clouse; P W Adams; C G Orosz
Journal:  J Clin Microbiol       Date:  1989-10       Impact factor: 5.948

8.  Expression of human cytokines dramatically improves reconstitution of specific human-blood lineage cells in humanized mice.

Authors:  Qingfeng Chen; Maroun Khoury; Jianzhu Chen
Journal:  Proc Natl Acad Sci U S A       Date:  2009-12-04       Impact factor: 11.205

9.  CD4+ T cell-derived IL-2 signals during early priming advances primary CD8+ T cell responses.

Authors:  Yo-Ping Lai; Chia-Ching Lin; Wan-Jung Liao; Chih-Yung Tang; Shu-Ching Chen
Journal:  PLoS One       Date:  2009-11-10       Impact factor: 3.240

10.  Design and modification of EGF4KDEL 7Mut, a novel bispecific ligand-directed toxin, with decreased immunogenicity and potent anti-mesothelioma activity.

Authors:  B J Stish; S Oh; H Chen; A Z Dudek; R A Kratzke; D A Vallera
Journal:  Br J Cancer       Date:  2009-10-06       Impact factor: 9.075
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