Literature DB >> 34932114

Effectiveness of mRNA Vaccines Against COVID-19 Hospitalization by Age and Chronic Medical Conditions Burden Among Immunocompetent US Adults, March-August 2021.

Nathaniel M Lewis1, Eric A Naioti1, Wesley H Self2, Adit A Ginde3, David J Douin3, H Keipp Talbot2, Jonathan D Casey2, Nicholas M Mohr4, Anne Zepeski4, Manjusha Gaglani5,6, Shekhar A Ghamande5, Tresa A McNeal5, Nathan I Shapiro7, Kevin W Gibbs8, D Clark Files8, David N Hager9, Arber Shehu9, Matthew E Prekker10, Heidi L Erickson10, Michelle N Gong11, Amira Mohamed11, Daniel J Henning12, Jay S Steingrub13, Ithan D Peltan14, Samuel M Brown14, Emily T Martin15, Kinsley Hubel16, Catherine L Hough16, Laurence W Busse17, Caitlin C Ten Lohuis17, Abhijit Duggal18, Jennifer G Wilson19, Alexandra J Gordon19, Nida Qadir20, Steven Y Chang20, Christopher Mallow21, Carolina Rivas21, Hilary M Babcock22, Jennie H Kwon22, Matthew C Exline23, Natasha Halasa2, James D Chappell2, Adam S Lauring24, Carlos G Grijalva2, Todd W Rice2, Jillian P Rhoads2, William B Stubblefield2, Adrienne Baughman2, Kelsey N Womack2, Christopher J Lindsell2, Kimberly W Hart2, Yuwei Zhu2, Stephanie J Schrag1, Miwako Kobayashi1, Jennifer R Verani1, Manish M Patel1, Mark W Tenforde1.   

Abstract

Vaccine effectiveness (VE) against COVID-19 hospitalization was evaluated among immunocompetent adults (≥18 years) during March-August 2021 using a case-control design. Among 1669 hospitalized COVID-19 cases (11% fully vaccinated) and 1950 RT-PCR-negative controls (54% fully vaccinated), VE was 96% (95% confidence interval [CI], 93%-98%) among patients with no chronic medical conditions and 83% (95% CI, 76%-88%) among patients with ≥ 3 categories of conditions. VE was similar between those aged 18-64 years versus ≥65 years (P > .05). VE against severe COVID-19 was very high among adults without chronic conditions and lessened with increasing comorbidity burden. Published by Oxford University Press for the Infectious Diseases Society of America 2021.

Entities:  

Keywords:  COVID-19; chronic medical conditions; preexisting conditions; vaccine effectiveness

Mesh：

Substances：

Year:  2022        PMID： 34932114      PMCID： PMC9113447          DOI： 10.1093/infdis/jiab619

Source DB:  PubMed          Journal:  J Infect Dis        ISSN： 0022-1899            Impact factor:   7.759


  10 in total

1.  Association Between mRNA Vaccination and COVID-19 Hospitalization and Disease Severity.

Authors:  Mark W Tenforde; Wesley H Self; Katherine Adams; Manjusha Gaglani; Adit A Ginde; Tresa McNeal; Shekhar Ghamande; David J Douin; H Keipp Talbot; Jonathan D Casey; Nicholas M Mohr; Anne Zepeski; Nathan I Shapiro; Kevin W Gibbs; D Clark Files; David N Hager; Arber Shehu; Matthew E Prekker; Heidi L Erickson; Matthew C Exline; Michelle N Gong; Amira Mohamed; Daniel J Henning; Jay S Steingrub; Ithan D Peltan; Samuel M Brown; Emily T Martin; Arnold S Monto; Akram Khan; Catherine L Hough; Laurence W Busse; Caitlin C Ten Lohuis; Abhijit Duggal; Jennifer G Wilson; Alexandra June Gordon; Nida Qadir; Steven Y Chang; Christopher Mallow; Carolina Rivas; Hilary M Babcock; Jennie H Kwon; Natasha Halasa; James D Chappell; Adam S Lauring; Carlos G Grijalva; Todd W Rice; Ian D Jones; William B Stubblefield; Adrienne Baughman; Kelsey N Womack; Jillian P Rhoads; Christopher J Lindsell; Kimberly W Hart; Yuwei Zhu; Samantha M Olson; Miwako Kobayashi; Jennifer R Verani; Manish M Patel
Journal:  JAMA       Date:  2021-11-23       Impact factor: 157.335

2.  Efficacy of the mRNA-1273 SARS-CoV-2 Vaccine at Completion of Blinded Phase.

Authors:  Hana M El Sahly; Lindsey R Baden; Brandon Essink; Susanne Doblecki-Lewis; Judith M Martin; Evan J Anderson; Thomas B Campbell; Jesse Clark; Lisa A Jackson; Carl J Fichtenbaum; Marcus Zervos; Bruce Rankin; Frank Eder; Gregory Feldman; Christina Kennelly; Laurie Han-Conrad; Michael Levin; Kathleen M Neuzil; Lawrence Corey; Peter Gilbert; Holly Janes; Dean Follmann; Mary Marovich; Laura Polakowski; John R Mascola; Julie E Ledgerwood; Barney S Graham; Allison August; Heather Clouting; Weiping Deng; Shu Han; Brett Leav; Deb Manzo; Rolando Pajon; Florian Schödel; Joanne E Tomassini; Honghong Zhou; Jacqueline Miller
Journal:  N Engl J Med       Date:  2021-09-22       Impact factor: 176.079

3.  Comparative Effectiveness of Moderna, Pfizer-BioNTech, and Janssen (Johnson & Johnson) Vaccines in Preventing COVID-19 Hospitalizations Among Adults Without Immunocompromising Conditions - United States, March-August 2021.

Authors:  Wesley H Self; Mark W Tenforde; Jillian P Rhoads; Manjusha Gaglani; Adit A Ginde; David J Douin; Samantha M Olson; H Keipp Talbot; Jonathan D Casey; Nicholas M Mohr; Anne Zepeski; Tresa McNeal; Shekhar Ghamande; Kevin W Gibbs; D Clark Files; David N Hager; Arber Shehu; Matthew E Prekker; Heidi L Erickson; Michelle N Gong; Amira Mohamed; Daniel J Henning; Jay S Steingrub; Ithan D Peltan; Samuel M Brown; Emily T Martin; Arnold S Monto; Akram Khan; Catherine L Hough; Laurence W Busse; Caitlin C Ten Lohuis; Abhijit Duggal; Jennifer G Wilson; Alexandra June Gordon; Nida Qadir; Steven Y Chang; Christopher Mallow; Carolina Rivas; Hilary M Babcock; Jennie H Kwon; Matthew C Exline; Natasha Halasa; James D Chappell; Adam S Lauring; Carlos G Grijalva; Todd W Rice; Ian D Jones; William B Stubblefield; Adrienne Baughman; Kelsey N Womack; Christopher J Lindsell; Kimberly W Hart; Yuwei Zhu; Lisa Mills; Sandra N Lester; Megan M Stumpf; Eric A Naioti; Miwako Kobayashi; Jennifer R Verani; Natalie J Thornburg; Manish M Patel
Journal:  MMWR Morb Mortal Wkly Rep       Date:  2021-09-24       Impact factor: 35.301

4.  The Effectiveness of the Two-Dose BNT162b2 Vaccine: Analysis of Real-World Data.

Authors:  Gabriel Chodick; Lilac Tene; Ran S Rotem; Tal Patalon; Sivan Gazit; Amir Ben-Tov; Clara Weil; Inbal Goldshtein; Gilad Twig; Dani Cohen; Khitam Muhsen
Journal:  Clin Infect Dis       Date:  2022-02-11       Impact factor: 9.079

5.  High antibody response to two-dose SARS-CoV-2 messenger RNA vaccination in patients with rheumatic and musculoskeletal diseases.

Authors:  Jake A Ruddy; Caoilfhionn Marie Connolly; Brian J Boyarsky; William A Werbel; Lisa Christopher-Stine; Jacqueline Garonzik-Wang; Dorry L Segev; Julie J Paik
Journal:  Ann Rheum Dis       Date:  2021-05-24       Impact factor: 19.103

6.  Initial observations on age, gender, BMI and hypertension in antibody responses to SARS-CoV-2 BNT162b2 vaccine.

Authors:  Raul Pellini; Aldo Venuti; Fulvia Pimpinelli; Elva Abril; Giovanni Blandino; Flaminia Campo; Laura Conti; Armando De Virgilio; Federico De Marco; Enea Gino Di Domenico; Ornella Di Bella; Simona Di Martino; Fabrizio Ensoli; Diana Giannarelli; Chiara Mandoj; Valentina Manciocco; Paolo Marchesi; Francesco Mazzola; Silvia Moretto; Gerardo Petruzzi; Fabrizio Petrone; Barbara Pichi; Martina Pontone; Jacopo Zocchi; Antonello Vidiri; Branka Vujovic; Giulia Piaggio; Aldo Morrone; Gennaro Ciliberto
Journal:  EClinicalMedicine       Date:  2021-06-04

7.  Prevalence of Multiple Chronic Conditions Among US Adults, 2018.

Authors:  Peter Boersma; Lindsey I Black; Brian W Ward
Journal:  Prev Chronic Dis       Date:  2020-09-17       Impact factor: 2.830

8.  Efficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine.

Authors:  Lindsey R Baden; Hana M El Sahly; Brandon Essink; Karen Kotloff; Sharon Frey; Rick Novak; David Diemert; Stephen A Spector; Nadine Rouphael; C Buddy Creech; John McGettigan; Shishir Khetan; Nathan Segall; Joel Solis; Adam Brosz; Carlos Fierro; Howard Schwartz; Kathleen Neuzil; Larry Corey; Peter Gilbert; Holly Janes; Dean Follmann; Mary Marovich; John Mascola; Laura Polakowski; Julie Ledgerwood; Barney S Graham; Hamilton Bennett; Rolando Pajon; Conor Knightly; Brett Leav; Weiping Deng; Honghong Zhou; Shu Han; Melanie Ivarsson; Jacqueline Miller; Tal Zaks
Journal:  N Engl J Med       Date:  2020-12-30       Impact factor: 91.245

9.  COVID-19 Vaccination Coverage Among Adults - United States, December 14, 2020-May 22, 2021.

Authors:  Jill Diesel; Natalie Sterrett; Sharoda Dasgupta; Jennifer L Kriss; Vaughn Barry; Kayla Vanden Esschert; Ari Whiteman; Betsy L Cadwell; Daniel Weller; Judith R Qualters; LaTreace Harris; Achal Bhatt; Charnetta Williams; LeAnne M Fox; Dana Meaney Delman; Carla L Black; Kamil E Barbour
Journal:  MMWR Morb Mortal Wkly Rep       Date:  2021-06-25       Impact factor: 17.586

Review 10.  Immunological mechanisms of vaccine-induced protection against COVID-19 in humans.

Authors:  Arnaud Marchant; Tobias R Kollmann; Manish Sadarangani
Journal:  Nat Rev Immunol       Date:  2021-07-01       Impact factor: 53.106
  10 in total
  4 in total

Review 1.  Roadmap for Sex-Responsive Influenza and COVID-19 Vaccine Research in Older Adults.

Authors:  Janna R Shapiro; Rosemary Morgan; Sean X Leng; Sabra L Klein
Journal:  Front Aging       Date:  2022-02-11

2.  Attitudes toward COVID-19 Vaccines among Patients with Complex Non-Communicable Disease and Their Caregivers in Rural Malawi.

Authors:  Moses Banda Aron; Emilia Connolly; Kaylin Vrkljan; Haules Robbins Zaniku; Revelation Nyirongo; Bright Mailosi; Todd Ruderman; Dale A Barnhart
Journal:  Vaccines (Basel)       Date:  2022-05-17

3.  The variant-specific burden of SARS-CoV-2 in Michigan: March 2020 through November 2021.

Authors:  Joshua G Petrie; Marisa C Eisenberg; Adam S Lauring; Julie Gilbert; Samantha M Harrison; Peter M DeJonge; Emily T Martin
Journal:  J Med Virol       Date:  2022-07-14       Impact factor: 20.693

4.  Success4life Youth Empowerment for Promoting Well-being and Boosting Mental Health: Protocol for an Experimental Study.

Authors:  Sajita Setia; Daniel Furtner; Mounir Bendahmane; Michelle Tichy
Journal:  JMIR Res Protoc       Date:  2022-09-14
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.