Literature DB >> 3492970

Effects of dietary supplementation on autoimmunity in the MRL/lpr mouse: a preliminary investigation.

D G Godfrey, W H Stimson, J Watson, J F Belch, R D Sturrock.   

Abstract

The effects of dietary fatty acid supplementation on various disease parameters in the spontaneously autoimmune MRL-mp-lpr/lpr mouse model of systemic lupus erythematosus before onset of disease were investigated. A fat deficient diet was supplemented with the following oils: olive oil, sunflower oil, evening primrose oil (EPO), fish oil, and a fish oil/EPO mixture. The mice receiving a diet enriched with EPO showed an increase in survival, as did those receiving the fish oil/EPO mixture. These results, taken together with those of the other parameters monitored, suggest that EPO may be of benefit in alleviating the murine form of the disease.

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Year:  1986        PMID： 3492970      PMCID： PMC1002043          DOI： 10.1136/ard.45.12.1019

Source DB:  PubMed          Journal:  Ann Rheum Dis        ISSN： 0003-4967            Impact factor:   19.103


  15 in total

1.  Influence of dietary restriction on immunologic function and renal disease in (NZB x NZW) F1 mice.

Authors:  G Fernandes; P Friend; E J Yunis; R A Good
Journal:  Proc Natl Acad Sci U S A       Date:  1978-03       Impact factor: 11.205

Review 2.  Etiopathogenesis of murine SLE.

Authors:  A N Theofilopoulos; F J Dixon
Journal:  Immunol Rev       Date:  1981       Impact factor: 12.988

3.  Modulation of inflammatory reactions by prostaglandins.

Authors:  S L Kunkel; J C Fantone; P A Ward; R B Zurier
Journal:  Prog Lipid Res       Date:  1981       Impact factor: 16.195

4.  Tetraene and pentaene leukotrienes: selective production from murine mastocytoma cells after dietary manipulation.

Authors:  R C Murphy; W C Pickett; B R Culp; W E Lands
Journal:  Prostaglandins       Date:  1981-10

5.  Dietary enrichment with the polyunsaturated fatty acid eicosapentaenoic acid prevents proteinuria and prolongs survival in NZB x NZW F1 mice.

Authors:  J D Prickett; D R Robinson; A D Steinberg
Journal:  J Clin Invest       Date:  1981-08       Impact factor: 14.808

6.  Homeostatic control of membrane fatty acid composition in the rat after dietary lipid treatment.

Authors:  R A Gibson; E J McMurchie; J S Charnock; G M Kneebone
Journal:  Lipids       Date:  1984-12       Impact factor: 1.880

7.  Influence of diet on survival of mice.

Authors:  G Fernandes; E J Yunis; R A Good
Journal:  Proc Natl Acad Sci U S A       Date:  1976-04       Impact factor: 11.205

8.  The effect of a fish diet on serum lipids in healthy human subjects.

Authors:  T O von Lossonczy; A Ruiter; H C Bronsgeest-Schoute; C M van Gent; R J Hermus
Journal:  Am J Clin Nutr       Date:  1978-08       Impact factor: 7.045

9.  Effect on blood lipids and haemostasis of a supplement of cod-liver oil, rich in eicosapentaenoic and docosahexaenoic acids, in healthy young men.

Authors:  T A Sanders; M Vickers; A P Haines
Journal:  Clin Sci (Lond)       Date:  1981-09       Impact factor: 6.124

10.  Design and analysis of randomized clinical trials requiring prolonged observation of each patient. II. analysis and examples.

Authors:  R Peto; M C Pike; P Armitage; N E Breslow; D R Cox; S V Howard; N Mantel; K McPherson; J Peto; P G Smith
Journal:  Br J Cancer       Date:  1977-01       Impact factor: 7.640
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  2 in total

1.  Dietary fish oil and the severity of symptoms in patients with systemic lupus erythematosus.

Authors:  A J Walton; M L Snaith; M Locniskar; A G Cumberland; W J Morrow; D A Isenberg
Journal:  Ann Rheum Dis       Date:  1991-07       Impact factor: 19.103

2.  Long-term treatment of the MRL/lpr mouse with methotrexate and 10-deazaaminopterin.

Authors:  J E Baggott; S L Morgan; L E Freeberg; B B Hudson; W H Vaughn; M Gopal Nair; C L Krumdieck; W J Koopman; R E Gay; S Gay
Journal:  Agents Actions       Date:  1992-01
  2 in total

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