Literature DB >> 34928191

A tentative assessment of the changes in transmissibility and fatality risk associated with Beta SARS-CoV-2 variants in South Africa: an ecological study.

Shi Zhao1,2, Zhihang Peng3, Maggie H Wang1,2.   

Abstract

The circulation of SARS-CoV-2 Beta (B.1.351) variants challenged the control of COVID-19 pandemic. The numbers of COVID-19 cases and deaths and SARS-CoV-2 sequences in South Africa were collected. We reconstructed the variant-specified reproduction numbers (R t) and delay-adjusted case fatality ratio (CFR) to examine the changes in transmissibility and fatality risk of Beta over non-Beta variants. We estimated that Beta variants were 41% (95%CI: 16, 73) more transmissible and 53% (95%CI: 6, 108) more fatal than non-Beta variants. Higher risks of infection and fatality might lead to increasing volumes of infections and critical patients.

Entities:  

Keywords:  COVID-19; South Africa; beta variants; case fatality; reproduction number; statistical modeling

Mesh：

Year:  2021        PMID： 34928191      PMCID： PMC9090418          DOI： 10.1080/20477724.2021.2014236

Source DB:  PubMed          Journal:  Pathog Glob Health        ISSN： 2047-7724            Impact factor:   3.735


  5 in total

1.  Inferring the Association between the Risk of COVID-19 Case Fatality and N501Y Substitution in SARS-CoV-2.

Authors:  Shi Zhao; Jingzhi Lou; Marc K C Chong; Lirong Cao; Hong Zheng; Zigui Chen; Renee W Y Chan; Benny C Y Zee; Paul K S Chan; Maggie H Wang
Journal:  Viruses       Date:  2021-04-08       Impact factor: 5.048

2.  Lack of detail in population-level data impedes analysis of SARS-CoV-2 variants of concern and clinical outcomes.

Authors:  Sean Wei Xiang Ong; Barnaby Edward Young; David Chien Lye
Journal:  Lancet Infect Dis       Date:  2021-04-12       Impact factor: 25.071

3.  Quantifying the transmission advantage associated with N501Y substitution of SARS-CoV-2 in the UK: an early data-driven analysis.

Authors:  Shi Zhao; Jingzhi Lou; Lirong Cao; Hong Zheng; Marc K C Chong; Zigui Chen; Renee W Y Chan; Benny C Y Zee; Paul K S Chan; Maggie H Wang
Journal:  J Travel Med       Date:  2021-02-23       Impact factor: 8.490

4.  The SARS-CoV-2 B.1.351 lineage (VOC β) is outgrowing the B.1.1.7 lineage (VOC α) in some French regions in April 2021.

Authors:  Bénédicte Roquebert; Sabine Trombert-Paolantoni; Stéphanie Haim-Boukobza; Emmanuel Lecorche; Laura Verdurme; Vincent Foulongne; Mircea T Sofonea; Samuel Alizon
Journal:  Euro Surveill       Date:  2021-06

5.  Increased transmissibility and global spread of SARS-CoV-2 variants of concern as at June 2021.

Authors:  Finlay Campbell; Brett Archer; Henry Laurenson-Schafer; Yuka Jinnai; Franck Konings; Neale Batra; Boris Pavlin; Katelijn Vandemaele; Maria D Van Kerkhove; Thibaut Jombart; Oliver Morgan; Olivier le Polain de Waroux
Journal:  Euro Surveill       Date:  2021-06
  5 in total

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