Literature DB >> 3492778

Impaired lymphocyte responsiveness to phytohaemagglutinin associated with the possession of HLA-B8/DR3.

A Amer, G Singh, C Darke, A E Dolby.   

Abstract

An examination was made of blastogenic response to phytohaemagglutinin (PHA) in HLA-B8 and/or DR3 positive subjects and B8/DR3 negative individuals. Both B8 and DR3 antigens were associated with a depression of the response at all three doses of PHA used. The possession of both these antigens did not lead to a further depression of the response.

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Year:  1986        PMID: 3492778     DOI: 10.1111/j.1399-0039.1986.tb00482.x

Source DB:  PubMed          Journal:  Tissue Antigens        ISSN: 0001-2815


  2 in total

1.  Mechanism of a lymphocyte abnormality associated with HLA-B8/DR3: role of interleukin-1.

Authors:  S Hashimoto; J P Michalski; M A Berman; C McCombs
Journal:  Clin Exp Immunol       Date:  1990-02       Impact factor: 4.330

2.  The immune response to hepatitis B vaccine in humans: inheritance patterns in families.

Authors:  M S Kruskall; C A Alper; Z Awdeh; E J Yunis; D Marcus-Bagley
Journal:  J Exp Med       Date:  1992-02-01       Impact factor: 14.307

  2 in total

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