Literature DB >> 34926232

A giant tumor of the mediastinum mixed with thymocytes and adipocytes: a case report.

Hui Wang1, Qiao Li2, Qichang Jiang1, Yanmiao Yang1, Yang Liu1, Longfeng Gu1, Ming Gong2, Gang Xu1, Cheng Chen2.   

Abstract

A 17-year-old male was hospitalized for 6 months with chest tightness and shortness of breath. Chest CT showed large mixed density shadow of anterior mediastinum, multiple flaky fat density shadow, left lower lung compression, atelectasis, partial compression of right lung and obvious heart pressure. The patient's symptoms are caused by the compression of the heart and lung by the mediastinal mass. The results of routine examination were normal. After excluding surgical contraindications, the patient underwent resection of a huge mediastinal tumor before median thoracotomy. The operation was smooth and the intraoperative vital signs were stable. The symptoms of chest tightness and shortness of breath disappeared after operation. The size of the tumor tissue removed after operation was about 45×30×25 cm3 and the weight was about 3.7 kg. The pathological diagnosis was thymolipoma. Postoperative reexamination of chest CT showed that the heart and lungs returned to the normal position. In this case, the operation is effective for large thymic tumors, and the symptoms of the patients are significantly relieved. Early diagnosis and surgical treatment are the key to improve the prognosis of patients. In this study, we reported a successful removal of a giant thymolipoma with complete disappearance of symptoms and no serious complications such as myasthenia gravis, aplastic anemia, and vitamin B12 deficiency. 2021 Gland Surgery. All rights reserved.

Entities:  

Keywords:  Thymectomy; case report; thymolipoma; thymus neoplasms

Year:  2021        PMID: 34926232      PMCID: PMC8637071          DOI: 10.21037/gs-21-651

Source DB:  PubMed          Journal:  Gland Surg        ISSN: 2227-684X


  12 in total

1.  Huge mediastinal mass with minimal symptoms: thymolipoma.

Authors:  Y Ganesh; Vivek Yadala; Y Nalini; Avinash Dal; Anil Dronam Raju
Journal:  BMJ Case Rep       Date:  2011-03-24

2.  A case of thymolipoma with observations on a possible relationship to intrathoracic lipomata.

Authors:  G F M HALL
Journal:  Br J Surg       Date:  1949-01       Impact factor: 6.939

3.  Which way is up? Policies and procedures for surgeons and pathologists regarding resection specimens of thymic malignancy.

Authors:  Frank C Detterbeck; Cesar Moran; James Huang; Saul Suster; Garrett Walsh; Lawrence Kaiser; Mark Wick
Journal:  J Thorac Oncol       Date:  2011-07       Impact factor: 15.609

Review 4.  Lipomatous Soft-tissue Tumors.

Authors:  Christopher N Johnson; Alice S Ha; Eleanor Chen; Darin Davidson
Journal:  J Am Acad Orthop Surg       Date:  2018-11-15       Impact factor: 3.020

Review 5.  Lipomatoses.

Authors:  Philipp Al Ghazal; Lisa-Lena Grönemeyer; Michael P Schön
Journal:  J Dtsch Dermatol Ges       Date:  2018-02-12       Impact factor: 5.584

6.  Diagnosis, treatment and prognosis of thymoma: an analysis of 116 cases.

Authors:  Yunxi Wang; Yu'e Sun; Jun Zhang; Naikang Zhou; Ying Liu; Xianghong Li; Yanjie Xu
Journal:  Chin Med J (Engl)       Date:  2003-08       Impact factor: 2.628

7.  Thymolipoma: analysis of 27 cases.

Authors:  M L Rosado-de-Christenson; R D Pugatch; C A Moran; J Galobardes
Journal:  Radiology       Date:  1994-10       Impact factor: 11.105

8.  Analysis of outcomes following surgical treatment of thymolipomatous myasthenia gravis: comparison with thymomatous and non-thymomatous myasthenia gravis.

Authors:  Chien-Sheng Huang; Wing-Yin Li; Pei-Chen Lee; Ko-Pei Kao; Teh-Ying Chou; Mei-Han Wu; Han-Shui Hsu; Yu-Chung Wu; Wen-Hu Hsu; Biing-Shiun Huang
Journal:  Interact Cardiovasc Thorac Surg       Date:  2013-12-22

9.  Well-differentiated liposarcoma primary from thymic stroma: Case report and literature review.

Authors:  Karina Furlan; Ira Miller; Prih Rohra; Fatima Mir; Fernando A Ocampo Gonzalez; Paolo Gattuso
Journal:  Exp Mol Pathol       Date:  2020-08-10       Impact factor: 3.362

10.  Thymolipoma Association with Myasthenia Gravis: Case Report.

Authors:  Sharifah A Othman; Othman Y AlFrayyan; Zeead M AlGhamdi; Fahd Makhdom; Yasser AlJehani; Hatem Y Elbawab; Mohamed El-Shawarby
Journal:  Am J Case Rep       Date:  2020-08-03
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