Literature DB >> 34923831

Targeting Inflammation in Pulmonary Artery Hypertension: Is It Time to Forget About the Lungs?

Douglas L Mann1.   

Abstract

Entities:  

Keywords:  Editorials; cytokines; inflammation; pulmonary artery

Mesh：

Year:  2021        PMID： 34923831      PMCID： PMC8766894          DOI： 10.1161/CIRCHEARTFAILURE.121.009290

Source DB:  PubMed          Journal:  Circ Heart Fail        ISSN： 1941-3289            Impact factor:   8.790


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  11 in total

1.  Loss of a gp130 cardiac muscle cell survival pathway is a critical event in the onset of heart failure during biomechanical stress.

Authors:  H Hirota; J Chen; U A Betz; K Rajewsky; Y Gu; J Ross; W Müller; K R Chien
Journal:  Cell       Date:  1999-04-16       Impact factor: 41.582

Review 2.  Inflammation and immunity in the pathogenesis of pulmonary arterial hypertension.

Authors:  Marlene Rabinovitch; Christophe Guignabert; Marc Humbert; Mark R Nicolls
Journal:  Circ Res       Date:  2014-06-20       Impact factor: 17.367

3.  IL-6 in pulmonary hypertension: why novel is not always best.

Authors:  Mark Toshner; Alex Rothman
Journal:  Eur Respir J       Date:  2020-04-16       Impact factor: 16.671

4.  Inflammatory Glycoprotein 130 Signaling Links Changes in Microtubules and Junctophilin-2 to Altered Mitochondrial Metabolism and Right Ventricular Contractility.

Authors:  Sasha Z Prisco; Lynn M Hartweck; Lauren Rose; Patricia D A Lima; Thenappan Thenappan; Stephen L Archer; Kurt W Prins
Journal:  Circ Heart Fail       Date:  2021-12-20       Impact factor: 10.447

Review 5.  gp130: a promising drug target for cancer therapy.

Authors:  Shili Xu; Nouri Neamati
Journal:  Expert Opin Ther Targets       Date:  2013-10-07       Impact factor: 6.902

6.  Discovery of a novel orally active small-molecule gp130 inhibitor for the treatment of ovarian cancer.

Authors:  Shili Xu; Fedora Grande; Antonio Garofalo; Nouri Neamati
Journal:  Mol Cancer Ther       Date:  2013-03-27       Impact factor: 6.261

Review 7.  Survival pathways in hypertrophy and heart failure: the gp130-STAT3 axis.

Authors:  P Fischer; D Hilfiker-Kleiner
Journal:  Basic Res Cardiol       Date:  2007-05-29       Impact factor: 17.165

8.  Diagnosis, Treatment, and Clinical Management of Pulmonary Arterial Hypertension in the Contemporary Era: A Review.

Authors:  Bradley A Maron; Nazzareno Galiè
Journal:  JAMA Cardiol       Date:  2016-12-01       Impact factor: 14.676

9.  gp130 Controls Cardiomyocyte Proliferation and Heart Regeneration.

Authors:  Yandong Li; Jie Feng; Shen Song; Haotong Li; Huijun Yang; Bin Zhou; Yan Li; Zhang Yue; Hong Lian; Lihui Liu; Shengshou Hu; Yu Nie
Journal:  Circulation       Date:  2020-06-30       Impact factor: 29.690

10.  Microtubule-Mediated Misregulation of Junctophilin-2 Underlies T-Tubule Disruptions and Calcium Mishandling in mdx Mice.

Authors:  Kurt W Prins; Michelle L Asp; Huiliang Zhang; Wang Wang; Joseph M Metzger
Journal:  JACC Basic Transl Sci       Date:  2016-04-18
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