INTRODUCTION: The prevalence of obesity is high and increasing worldwide. Obesity is generally associated with an increased risk of chronic disease and mortality. The objective of the study was to test the effect of a lifestyle intervention on body weight and other chronic disease risk markers. METHODS: A non-randomized controlled trial was conducted, including mostly middle-aged and elderly participants recruited from the general population in rural northwest Germany (intervention: n = 114; control: n = 87). The intervention consisted of a 1-year lifestyle programme, focussing on four key areas: a largely plant-based diet (strongest emphasis), physical activity, stress management, and community support. Parameters were assessed at baseline, 10 weeks, 6 months, and 1 year. The control group received no intervention. RESULTS: Compared to the control, in the intervention group, significantly lower 1-year trajectories were observed for body weight, body mass index (BMI), waist circumference (WC), total cholesterol, calculated LDL cholesterol, non-HDL cholesterol, remnant cholesterol (REM-C), glucose, HbA1c, and resting heart rate (RHR). However, between-group differences at 1 year were small for glucose, HbA1c, and cholesterol (apart from REM-C). No significant between-group differences were found for 1-year trajectories of measured LDL cholesterol, HDL cholesterol, triglycerides, insulin, blood pressure, and pulse pressure. CONCLUSION: The intervention successfully reduced body weight, BMI, WC, REM-C, and RHR. However, at 1 year, effectiveness of the intervention regarding other risk markers was either very modest or could not be shown.
INTRODUCTION: The prevalence of obesity is high and increasing worldwide. Obesity is generally associated with an increased risk of chronic disease and mortality. The objective of the study was to test the effect of a lifestyle intervention on body weight and other chronic disease risk markers. METHODS: A non-randomized controlled trial was conducted, including mostly middle-aged and elderly participants recruited from the general population in rural northwest Germany (intervention: n = 114; control: n = 87). The intervention consisted of a 1-year lifestyle programme, focussing on four key areas: a largely plant-based diet (strongest emphasis), physical activity, stress management, and community support. Parameters were assessed at baseline, 10 weeks, 6 months, and 1 year. The control group received no intervention. RESULTS: Compared to the control, in the intervention group, significantly lower 1-year trajectories were observed for body weight, body mass index (BMI), waist circumference (WC), total cholesterol, calculated LDL cholesterol, non-HDL cholesterol, remnant cholesterol (REM-C), glucose, HbA1c, and resting heart rate (RHR). However, between-group differences at 1 year were small for glucose, HbA1c, and cholesterol (apart from REM-C). No significant between-group differences were found for 1-year trajectories of measured LDL cholesterol, HDL cholesterol, triglycerides, insulin, blood pressure, and pulse pressure. CONCLUSION: The intervention successfully reduced body weight, BMI, WC, REM-C, and RHR. However, at 1 year, effectiveness of the intervention regarding other risk markers was either very modest or could not be shown.
Authors: Nishaki K Mehta; Jarred Strickling; Erica Mark; Sarah Swineheart; Joseph Puthumana; Carl J Lavie; David E Haines; Barry A Franklin Journal: Prog Cardiovasc Dis Date: 2021-05-20 Impact factor: 8.194
Authors: Susan J Curry; Alex H Krist; Douglas K Owens; Michael J Barry; Aaron B Caughey; Karina W Davidson; Chyke A Doubeni; John W Epling; David C Grossman; Alex R Kemper; Martha Kubik; C Seth Landefeld; Carol M Mangione; Maureen G Phipps; Michael Silverstein; Melissa A Simon; Chien-Wen Tseng; John B Wong Journal: JAMA Date: 2018-09-18 Impact factor: 56.272
Authors: Caterina Bonfiglio; Carla M Leone; Liciana V A Silveira; Rocco Guerra; Giovanni Misciagna; Maria G Caruso; Irene Bruno; Claudia Buongiorno; Angelo Campanella; Vito M B Guerra; Maria Notarnicola; Valentina Deflorio; Isabella Franco; Antonella Bianco; Antonella Mirizzi; Laura R Aballay; Anna M Cisternino; Paolo Sorino; Pasqua L Pesole; Alberto R Osella Journal: Nutr Metab Cardiovasc Dis Date: 2020-07-10 Impact factor: 4.222
Authors: Tammy Y N Tong; Paul N Appleby; Miranda E G Armstrong; Georgina K Fensom; Anika Knuppel; Keren Papier; Aurora Perez-Cornago; Ruth C Travis; Timothy J Key Journal: BMC Med Date: 2020-11-23 Impact factor: 8.775
Authors: Angelo Campanella; Palma A Iacovazzi; Giovanni Misciagna; Caterina Bonfiglio; Antonella Mirizzi; Isabella Franco; Antonella Bianco; Paolo Sorino; Maria G Caruso; Anna M Cisternino; Claudia Buongiorno; Rosalba Liuzzi; Alberto R Osella Journal: Nutrients Date: 2020-06-04 Impact factor: 5.717