Literature DB >> 3492214

Successful medical treatment of a corneal ulcer due to Acanthamoeba polyphaga.

T N Jackson, J B Heinze, J Tuxen, J M Weiner.   

Abstract

A 19-year-old man, who was a soft contact lens wearer for correction of myopia, presented with right corneal ulceration. The diagnosis of Acanthamoeba polyphaga infection was made by culture and serology. In-vitro sensitivity tests suggested that the organism was sensitive to Neosporin (polymyxin, neomycin and gramicidin) and natamycin. Topical therapy with these agents resulted in complete healing of the corneal ulcer in two months. To our knowledge, our patient is the only case of successful medical treatment of this condition that has achieved a good visual result.

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Year:  1986        PMID: 3492214     DOI: 10.1111/j.1442-9071.1986.tb00025.x

Source DB:  PubMed          Journal:  Aust N Z J Ophthalmol        ISSN: 0814-9763


  3 in total

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Authors:  Trivendra Tripathi; Hassan Alizadeh
Journal:  Receptors Clin Investig       Date:  2014

2.  Acanthamoeba keratitis associated with contact lenses: six consecutive cases of successful management.

Authors:  M B Moore; J P McCulley
Journal:  Br J Ophthalmol       Date:  1989-04       Impact factor: 4.638

3.  The Effect of Anti-Amoebic Agents and Ce6-PDT on Acanthamoeba castellanii Trophozoites and Cysts, In Vitro.

Authors:  Lei Shi; Vithusan Muthukumar; Tanja Stachon; Lorenz Latta; Mohamed Ibrahem Elhawy; Gubesh Gunaratnam; Erika Orosz; Berthold Seitz; Albrecht F Kiderlen; Markus Bischoff; Nóra Szentmáry
Journal:  Transl Vis Sci Technol       Date:  2020-11-23       Impact factor: 3.283

  3 in total

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