Literature DB >> 34921056

Harveian Oration 2020: Elucidation of molecular oxygen sensing mechanisms in human cells: implications for medicine.

Peter J Ratcliffe1.   

Abstract

Entities:  

Keywords:  HIF hydroxylase system; oxygen homeostasis; oxygen sensing

Mesh：

Substances：

Year:  2021        PMID： 34921056      PMCID： PMC8813027          DOI： 10.7861/clinmed.ed.22.1.harv

Source DB:  PubMed          Journal:  Clin Med (Lond)        ISSN： 1470-2118            Impact factor:   2.659


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  69 in total

1.  A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation.

Authors:  G L Semenza; G L Wang
Journal:  Mol Cell Biol       Date:  1992-12       Impact factor: 4.272

2.  The regulated expression of erythropoietin by two human hepatoma cell lines.

Authors:  M A Goldberg; G A Glass; J M Cunningham; H F Bunn
Journal:  Proc Natl Acad Sci U S A       Date:  1987-11       Impact factor: 11.205

3.  The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis.

Authors:  P H Maxwell; M S Wiesener; G W Chang; S C Clifford; E C Vaux; M E Cockman; C C Wykoff; C W Pugh; E R Maher; P J Ratcliffe
Journal:  Nature       Date:  1999-05-20       Impact factor: 49.962

4.  Control of T(H)17/T(reg) balance by hypoxia-inducible factor 1.

Authors:  Eric V Dang; Joseph Barbi; Huang-Yu Yang; Dilini Jinasena; Hong Yu; Ying Zheng; Zachary Bordman; Juan Fu; Young Kim; Hung-Rong Yen; Weibo Luo; Karen Zeller; Larissa Shimoda; Suzanne L Topalian; Gregg L Semenza; Chi V Dang; Drew M Pardoll; Fan Pan
Journal:  Cell       Date:  2011-08-25       Impact factor: 41.582

5.  Drosophila melanogaster SL2 cells contain a hypoxically inducible DNA binding complex which recognises mammalian HIF-binding sites.

Authors:  M Nagao; B L Ebert; P J Ratcliffe; C W Pugh
Journal:  FEBS Lett       Date:  1996-06-03       Impact factor: 4.124

6.  Expression of hypoxia-inducible factor-1alpha and -2alpha in hypoxic and ischemic rat kidneys.

Authors:  Christian Rosenberger; Stefano Mandriota; Jan Steffen Jürgensen; Michael S Wiesener; Jan H Hörstrup; Ulrich Frei; Peter J Ratcliffe; Patrick H Maxwell; Sebastian Bachmann; Kai-Uwe Eckardt
Journal:  J Am Soc Nephrol       Date:  2002-07       Impact factor: 10.121

7.  Hypoxia and mitochondrial inhibitors regulate expression of glucose transporter-1 via distinct Cis-acting sequences.

Authors:  B L Ebert; J D Firth; P J Ratcliffe
Journal:  J Biol Chem       Date:  1995-12-08       Impact factor: 5.157

8.  Homeostatic response to hypoxia is regulated by the N-end rule pathway in plants.

Authors:  Daniel J Gibbs; Seung Cho Lee; Nurulhikma Md Isa; Silvia Gramuglia; Takeshi Fukao; George W Bassel; Cristina Sousa Correia; Françoise Corbineau; Frederica L Theodoulou; Julia Bailey-Serres; Michael J Holdsworth
Journal:  Nature       Date:  2011-10-23       Impact factor: 49.962

9.  PHD2 inactivation in Type I cells drives HIF-2α-dependent multilineage hyperplasia and the formation of paraganglioma-like carotid bodies.

Authors:  James W Fielding; Emma J Hodson; Xiaotong Cheng; David J P Ferguson; Luise Eckardt; Julie Adam; Philomena Lip; Matthew Maton-Howarth; Indrika Ratnayaka; Christopher W Pugh; Keith J Buckler; Peter J Ratcliffe; Tammie Bishop
Journal:  J Physiol       Date:  2018-06-19       Impact factor: 5.182

10.  Regulation of ventilatory sensitivity and carotid body proliferation in hypoxia by the PHD2/HIF-2 pathway.

Authors:  Emma J Hodson; Lynn G Nicholls; Philip J Turner; Ronan Llyr; James W Fielding; Gillian Douglas; Indrika Ratnayaka; Peter A Robbins; Christopher W Pugh; Keith J Buckler; Peter J Ratcliffe; Tammie Bishop
Journal:  J Physiol       Date:  2015-10-06       Impact factor: 5.182
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  1 in total

1.  Do you need a weatherman to know which way the wind blows?

Authors:  Anton Emmanuel
Journal:  Clin Med (Lond)       Date:  2022-01       Impact factor: 2.659
  1 in total

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