| Literature DB >> 34918242 |
Chuan Loo Wong1, Chean Yeah Yong1, Khai Wooi Lee2.
Abstract
Bacteriophages have been explored for their uses in vaccine development, due to the ease of propagation while displaying epitopes in high density. Bacteriophage T7 has been demonstrated to be useful in the production of potential vaccine candidates for various diseases, including influenza A, foot-and mouth disease (FMD), and cancers. In this chapter, we described the use of phage T7 to display potential foot-and-mouth disease virus (FMDV) epitope, from cloning to expression, purification, and immunization in a mouse model.Entities:
Keywords: Bacteriophage T7; Foot-and-mouth disease virus (FMDV); Mice immunization; Phage T7 display; Phage vaccine
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Year: 2022 PMID： 34918242 DOI： 10.1007/978-1-0716-1892-9_5
Source DB: PubMed Journal: Methods Mol Biol ISSN： 1064-3745