Literature DB >> 34917183

Impact of modern personalized treatment of breast cancer on surgical attitude and outcomes.

Ciprian Tănăsescu1,2, Dragos Serban3,4, Andrei Moisin2, Carmen Popa2, Ramona Coca1,2, George Iancu5,6, Mihail Silviu Tudosie7,8, Daniel Ovidiu Costea9,10, Bogdan Socea3,11, Corneliu Tudor4, Gabriel Andrei Gangura3,12, Laura Carina Tribus13,14, Gabriel Catalin Smarandache3,4.   

Abstract

Multimodal treatment of breast cancer has made steady progress in recent years. The involvement of modern oncology, diagnostic imaging techniques and surgical treatment, have brought a definite benefit to patients, defining the multidisciplinary treatment of breast cancer. The introduction of immunohistochemical testing and genetic screening has led to the prioritization of therapy according to their results and a correct approach to initiating treatment. The main aim of the present study was to conduct a comparative analysis through a retrospective study of the therapeutic means used in breast cancer with the statistical evaluation of the obtained results. To carry out the study, a group of 125 patients hospitalized during the period January 2015 to December 2020, were included, and the parameters were selected from the observation sheets. The results of the study demonstrated the superiority of multimodal treatment of breast cancer over surgical treatment as the only therapeutic management. The introduction of ultrasound-guided biopsies and conservative surgical options has led to increased diagnostic accuracy and a significant improvement in aesthetic outcome. The multidisciplinary approach to breast cancer allows an individualized treatment by performing immunohistochemical testing and through the use of neoadjuvant and adjuvant treatment combined with conservative surgical techniques with a more favorable cosmetic and oncological result, with reduced postoperative complications.
Copyright © 2020, Spandidos Publications.

Entities:  

Keywords:  breast cancer; immunohistochemical analysis; multimodal therapy; neoadjuvant chemotherapy; outcomes; surgery

Year:  2021        PMID: 34917183      PMCID: PMC8630438          DOI: 10.3892/etm.2021.10979

Source DB:  PubMed          Journal:  Exp Ther Med        ISSN: 1792-0981            Impact factor:   2.447


  35 in total

1.  Increasing trends in the use of breast-conserving surgery in California.

Authors:  C R Morris; R Cohen; R Schlag; W E Wright
Journal:  Am J Public Health       Date:  2000-02       Impact factor: 9.308

2.  Patterns and correlates of adjuvant radiotherapy receipt after lumpectomy and after mastectomy for breast cancer.

Authors:  Reshma Jagsi; Paul Abrahamse; Monica Morrow; Sarah T Hawley; Jennifer J Griggs; John J Graff; Ann S Hamilton; Steven J Katz
Journal:  J Clin Oncol       Date:  2010-03-29       Impact factor: 44.544

3.  What could be the reasons of late diagnosis of breast cancer in Tunisia?

Authors:  L Ben Fatma; I Belaid; N Said; S Gahbiche; M Hochlef; I Chabchoub; F Ezzairi; S Ben Ahmed
Journal:  Tunis Med       Date:  2018 Oct-Nov

4.  Is Core Needle Biopsy Reliable in Differentiating Between Aggressive Benign and Malignant Radiolucent Bone Tumors?

Authors:  Vishal Hegde; Zachary D C Burke; Howard Y Park; Stephen D Zoller; Daniel Johansen; Benjamin V Kelley; Ben Levine; Kambiz Motamedi; Noah C Federman; Leanne L Seeger; Scott D Nelson; Nicholas M Bernthal
Journal:  Clin Orthop Relat Res       Date:  2018-03       Impact factor: 4.176

5.  Immunohistochemical detection of estrogen and progesterone receptor and HER2 expression in breast carcinomas: comparison of cell block and tissue block preparations.

Authors:  Sharenda L Williams; George G Birdsong; Cynthia Cohen; Momin T Siddiqui
Journal:  Int J Clin Exp Pathol       Date:  2009-01-20

6.  The impact of adjuvant radiotherapy on the survival of primary breast cancer patients: a retrospective multicenter cohort study of 8935 subjects.

Authors:  A Wöckel; R Wolters; T Wiegel; I Novopashenny; W Janni; R Kreienberg; M Wischnewsky; L Schwentner
Journal:  Ann Oncol       Date:  2014-02-09       Impact factor: 32.976

7.  Breast implants and breast cancer.

Authors:  Davood Mehrabani; Ail Manafi
Journal:  World J Plast Surg       Date:  2012-07

Review 8.  Endocrine and Targeted Therapy for Hormone-Receptor-Positive, HER2-Negative Advanced Breast Cancer: Insights to Sequencing Treatment and Overcoming Resistance Based on Clinical Trials.

Authors:  Rola El Sayed; Lara El Jamal; Sarah El Iskandarani; Jeries Kort; Mahmoud Abdel Salam; Hazem Assi
Journal:  Front Oncol       Date:  2019-06-21       Impact factor: 6.244

9.  Young age: an independent risk factor for disease-free survival in women with operable breast cancer.

Authors:  Wonshik Han; Seok Won Kim; In Ae Park; Daehee Kang; Sung-Won Kim; Yeo-Kyu Youn; Seung Keun Oh; Kuk Jin Choe; Dong-Young Noh
Journal:  BMC Cancer       Date:  2004-11-17       Impact factor: 4.430

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