Literature DB >> 3491672

Karyotypic evolution in a B-cell lymphoma.

P H Fitzgerald, C M Morris, I Rosman, S A Archer, P E Hollings.   

Abstract

A B-cell lymphoma in the lung of a 59-year-old woman showed a near-pentaploid karyotype and chromosomal changes indicating a t(8;14) in cells from a pleural aspirate. Cells from metastases to the skin and a second pleural aspirate were pseudodiploid, but showed separate further complex cytogenetic changes. Among these was a 14q+ chromosome, but the #8 chromosomes apparently were normal. It is suggested that there was a loss of the derivative 8q- chromosome from the t(8;14) followed by homozygozity of the normal #8 chromosome.

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Year:  1987        PMID: 3491672     DOI: 10.1016/0165-4608(87)90109-9

Source DB:  PubMed          Journal:  Cancer Genet Cytogenet        ISSN: 0165-4608


  1 in total

1.  Establishment and Molecular Cytogenetic Characterization of a Cell Culture Model of Head and Neck Squamous Cell Carcinoma (HNSCC).

Authors:  Verena L Bauer; Ludwig Hieber; Quirin Schaeffner; Johannes Weber; Herbert Braselmann; Reinhard Huber; Axel Walch; Horst Zitzelsberger
Journal:  Genes (Basel)       Date:  2010-11-11       Impact factor: 4.096

  1 in total

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