Xin Li1, Yu Li2, Jun Shao3, Yong Shao4, Zhi-Long Huang5. 1. School of Statistics, East China Normal University, Shanghai 200241, China. 2. Department of Andrology. 3. Department of Reproductive Medicine, Nantong Maternity and Child Health Hospital, Nantong, Jiangsu 226018, China. 4. Department of Reproductive Medicine, Nanjing School of Clinical Medicine, Southern Medical University / General Hospital of Eastern Theater Command, Nanjing, Jiangsu 210002, China. 5. Department of Urology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong 250021, China.
Abstract
OBJECTIVE: To investigate the trend of change in the sperm concentration of Chinese fertile males from 1984 to 2019. METHODS: We searched CNKI, CQVIP and Wanfang Database for literature relevant to human sperm concentration published from 1984 to 2019, and analyzed the trend of change in the sperm concentration of fertile men in China in the past 35 years. RESULTS: A total of 9 495 publications were identified, of which 73 with 11 606 subjects were included. Based on the results of fitting calculation, the perm concentration of the males declined significantly from 98.8486 ×10⁶/ml in 1984 to 72.5531 ×10⁶/ml in 2019, with a mean decrease of 0.7513 ×10⁶/ml annually (P < 0.01), and the reduction was more significant in North than in South China (－1.2754 vs －0.4587 ×10⁶/ml, P = 0.01). CONCLUSIONS: The sperm concentration of fertile Chinese men was decreasing in the past 35 years, which might be related to unhealthy living habits and environmental pollution.
OBJECTIVE: To investigate the trend of change in the sperm concentration of Chinese fertile males from 1984 to 2019. METHODS: We searched CNKI, CQVIP and Wanfang Database for literature relevant to human sperm concentration published from 1984 to 2019, and analyzed the trend of change in the sperm concentration of fertile men in China in the past 35 years. RESULTS: A total of 9 495 publications were identified, of which 73 with 11 606 subjects were included. Based on the results of fitting calculation, the perm concentration of the males declined significantly from 98.8486 ×10⁶/ml in 1984 to 72.5531 ×10⁶/ml in 2019, with a mean decrease of 0.7513 ×10⁶/ml annually (P < 0.01), and the reduction was more significant in North than in South China (－1.2754 vs －0.4587 ×10⁶/ml, P = 0.01). CONCLUSIONS: The sperm concentration of fertile Chinese men was decreasing in the past 35 years, which might be related to unhealthy living habits and environmental pollution.
Authors: W H Tang; C Y Deng; J M Gao; Z C Luo; H Wu; S L Tian; N Wei; B Li; Q C Zhao; J F Song; L Zhang; L L Ma; H Jiang Journal: Beijing Da Xue Xue Bao Yi Xue Ban Date: 2022-08-18