Literature DB >> 34913972

Surgical Treatment of Valvular Heart Disease in Nigeria: A 6-Year Experience.

Ikechukwu A Nwafor1, John C Eze1, Maureen N Nwafor2.   

Abstract

Surgical treatment of valvular heart disease in Nigeria, the most populous country in sub-Saharan Africa, is adversely affected by socioeconomic factors such as poverty and ignorance. To evaluate our experience in this context, we identified all patients who underwent surgery for acquired or congenital valvular heart disease at our Nigerian center from February 2013 through January 2019. We collected data from their medical records, including patient age and sex, pathophysiologic causes and types of valvular disease, surgical treatment, and outcomes. Ninety-three patients (43 males [46.2%]; mean age, 38.9 ± 10.0 yr [range, 11-80 yr]) underwent surgical treatment of a total of 122 diseased valves, including 72 (59.0%) mitral, 26 (21.3%) aortic, 21 (17.2%) tricuspid, and 3 (2.5%) pulmonary. The most prevalent pathophysiologic cause of disease was rheumatic (87 valves [71.3%]), followed by functional (20 [16.4%]), congenital (8 [6.6%]), degenerative (5 [4.1%]), and endocarditic (2 [1.6%]). All 3 diseased pulmonary valves had annular defects associated with congenital disease. Surgical treatment included mechanical prosthetic replacement of 92 valves (75.4%), surgical repair of 29 (23.8%), and bioprosthetic replacement of 1 (0.8%). We conclude that, in Nigeria, valvular disease is mainly rheumatic, affects mostly younger to middle-aged individuals, and is usually treated with prosthetic replacement.
© 2021 by the Texas Heart® Institute, Houston.

Entities:  

Keywords:  Cardiac surgical procedures; Nigeria; endocarditis; health services needs and demands; heart valve diseases/surgery; heart valve prosthesis implantation; retrospective studies; rheumatic heart disease; treatment outcome

Mesh:

Year:  2021        PMID: 34913972      PMCID: PMC8788635          DOI: 10.14503/THIJ-19-7080

Source DB:  PubMed          Journal:  Tex Heart Inst J        ISSN: 0730-2347


  46 in total

1.  Outcomes 15 years after valve replacement with a mechanical versus a bioprosthetic valve: final report of the Veterans Affairs randomized trial.

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Journal:  J Am Coll Cardiol       Date:  2000-10       Impact factor: 24.094

Review 2.  World Heart Federation criteria for echocardiographic diagnosis of rheumatic heart disease--an evidence-based guideline.

Authors:  Bo Reményi; Nigel Wilson; Andrew Steer; Beatriz Ferreira; Joseph Kado; Krishna Kumar; John Lawrenson; Graeme Maguire; Eloi Marijon; Mariana Mirabel; Ana Olga Mocumbi; Cleonice Mota; John Paar; Anita Saxena; Janet Scheel; John Stirling; Satupaitea Viali; Vijayalakshmi I Balekundri; Gavin Wheaton; Liesl Zühlke; Jonathan Carapetis
Journal:  Nat Rev Cardiol       Date:  2012-02-28       Impact factor: 32.419

3.  Open-heart surgery in Nigeria: indications and challenges.

Authors:  John C Eze; Ndubueze Ezemba
Journal:  Tex Heart Inst J       Date:  2007

4.  Evolution of mitral valve replacement in children: a 40-year experience.

Authors:  John W Brown; Andrew C Fiore; Mark Ruzmetov; Osama Eltayeb; Mark D Rodefeld; Mark W Turrentine
Journal:  Ann Thorac Surg       Date:  2011-12-07       Impact factor: 4.330

5.  Very long-term results (more than 20 years) of valve repair with carpentier's techniques in nonrheumatic mitral valve insufficiency.

Authors:  E Braunberger; A Deloche; A Berrebi; F Abdallah; J A Celestin; P Meimoun; G Chatellier; S Chauvaud; J N Fabiani; A Carpentier
Journal:  Circulation       Date:  2001-09-18       Impact factor: 29.690

6.  Four decades of experience with mitral valve repair: analysis of differential indications, technical evolution, and long-term outcome.

Authors:  Daniel J DiBardino; Andrew W ElBardissi; R Scott McClure; Ozwaldo A Razo-Vasquez; Nicole E Kelly; Lawrence H Cohn
Journal:  J Thorac Cardiovasc Surg       Date:  2010-01       Impact factor: 5.209

7.  Is rheumatic mitral valve repair still a feasible alternative?: indications, technique, and results.

Authors:  Ihsan Bakir; Burak Onan; Ismihan Selen Onan; Mehmet Gul; Nevzat Uslu
Journal:  Tex Heart Inst J       Date:  2013

8.  Late results after mitral valve replacement with bileaflet mechanical prosthesis in children: evaluation of prosthesis-patient mismatch.

Authors:  Munetaka Masuda; Hideaki Kado; Hideki Tatewaki; Yuichiro Shiokawa; Hisataka Yasui
Journal:  Ann Thorac Surg       Date:  2004-03       Impact factor: 4.330

Review 9.  Surgery for rheumatic mitral valve disease in sub-saharan African countries: why valve repair is still the best surgical option.

Authors:  Charles Mve Mvondo; Marta Pugliese; Alessandro Giamberti; David Chelo; Liliane Mfeukeu Kuate; Jerome Boombhi; Ellen Marie Dailor
Journal:  Pan Afr Med J       Date:  2016-08-11

10.  Open heart surgery in Nigeria; a work in progress.

Authors:  Bode Falase; Michael Sanusi; Adetinuwe Majekodunmi; Barakat Animasahun; Ifeoluwa Ajose; Ariyo Idowu; Adewale Oke
Journal:  J Cardiothorac Surg       Date:  2013-01-12       Impact factor: 1.637

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