Literature DB >> 3491221

Direct role of viral hemagglutinin in B-cell mitogenesis by influenza viruses.

P Poumbourios, E M Anders, A A Scalzo, D O White, A W Hampson, D C Jackson.   

Abstract

The mitogenic activity of influenza virus is a function of the hemagglutinin (HA) molecule. Purified HA is mitogenic for murine B lymphocytes but not T lymphocytes. Furthermore, like the intact virus, HA of the H2 (but not H3) subtype is mitogenic only for B cells expressing the class II major histocompatibility complex glycoprotein I-E. Since virus bearing uncleaved HA is as mitogenic as virus bearing cleaved HA, the membrane fusion activity of the HA molecule is not involved.

Entities:  

Mesh：

Substances：

Year:  1987        PMID： 3491221      PMCID： PMC255243          DOI： 10.1128/JVI.61.1.214-217.1987

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  16 in total

1.  Activation of influenza A viruses by trypsin treatment.

Authors:  H D Klenk; R Rott; M Orlich; J Blödorn
Journal:  Virology       Date:  1975-12       Impact factor: 3.616

2.  Influenza A viruses of the H2N2 subtype are lymphocyte mitogens.

Authors:  G M Butchko; R B Armstrong; W J Martin; F A Ennis
Journal:  Nature       Date:  1978-01-05       Impact factor: 49.962

3.  A rapid method for the isolation of functional thymus-derived murine lymphocytes.

Authors:  M H Julius; E Simpson; L A Herzenberg
Journal:  Eur J Immunol       Date:  1973-10       Impact factor: 5.532

4.  Identification of biological activities of paramyxovirus glycoproteins. Activation of cell fusion, hemolysis, and infectivity of proteolytic cleavage of an inactive precursor protein of Sendai virus.

Authors:  A Scheid; P W Choppin
Journal:  Virology       Date:  1974-02       Impact factor: 3.616

5.  Cleavage of structural proteins during the assembly of the head of bacteriophage T4.

Authors:  U K Laemmli
Journal:  Nature       Date:  1970-08-15       Impact factor: 49.962

6.  Mitogenicity of influenza hemagglutinin glycoproteins and influenza viruses bearing H2-hemagglutinin.

Authors:  R B Armstrong; G M Butchko; S C Kiley; M A Phelan; F A Ennis
Journal:  Infect Immun       Date:  1981-10       Impact factor: 3.441

7.  Influenza viruses cause hemolysis and fusion of cells.

Authors:  R T Huang; R Rott; H D Klenk
Journal:  Virology       Date:  1981-04-15       Impact factor: 3.616

8.  In vitro antibody response to influenza virus. I. T cell dependence of secondary response to hemagglutinin.

Authors:  E M Anders; P M Peppard; W H Burns; D O White
Journal:  J Immunol       Date:  1979-09       Impact factor: 5.422

9.  Relationship between mitogenic activity of influenza viruses and the receptor-binding specificity of their hemagglutinin molecules.

Authors:  E M Anders; A A Scalzo; G N Rogers; D O White
Journal:  J Virol       Date:  1986-11       Impact factor: 5.103

10.  Cell fusion by Semliki Forest, influenza, and vesicular stomatitis viruses.

Authors:  J White; K Matlin; A Helenius
Journal:  J Cell Biol       Date:  1981-06       Impact factor: 10.539
View more
  4 in total

1.  Major histocompatibility complex class II expression and hemagglutinin subtype influence the infectivity of type A influenza virus for respiratory dendritic cells.

Authors:  Kristian M Hargadon; Haixia Zhou; Randy A Albrecht; Haley A Dodd; Adolfo García-Sastre; Thomas J Braciale
Journal:  J Virol       Date:  2011-09-14       Impact factor: 5.103

2.  Gamma-irradiated influenza virus uniquely induces IFN-I mediated lymphocyte activation independent of the TLR7/MyD88 pathway.

Authors:  Yoichi Furuya; Jennifer Chan; En-Chi Wan; Aulikki Koskinen; Kerrilyn R Diener; John D Hayball; Matthias Regner; Arno Müllbacher; Mohammed Alsharifi
Journal:  PLoS One       Date:  2011-10-05       Impact factor: 3.240

Review 3.  Receptors and ligands involved in viral induction of type I interferon production by plasmacytoid dendritic cells.

Authors:  Rosalind E Seeds; Siamon Gordon; Joanna L Miller
Journal:  Immunobiology       Date:  2006-07-13       Impact factor: 3.144

Review 4.  Induction of interferon by virus glycoprotein(s) in lymphoid cells through interaction with the cellular receptors via lectin-like action: an alternative interferon induction mechanism.

Authors:  Y Ito
Journal:  Arch Virol       Date:  1994       Impact factor: 2.574
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.