Literature DB >> 34911540

Correction to: Epigenetic mediated zinc finger protein 671 downregulation promotes cell proliferation and tumorigenicity in nasopharyngeal carcinoma by inhibiting cell cycle arrest.

Jian Zhang1, Xin Wen1, Na Liu1, Ying-Qin Li1, Xin-Ran Tang1, Ya-Qin Wang1, Qing-Mei He1, Xiao-Jing Yang1, Pan-Pan Zhang1, Jun Ma2, Ying Sun3.   

Abstract

Entities:  

Year:  2021        PMID: 34911540      PMCID: PMC8672624          DOI: 10.1186/s13046-021-02205-0

Source DB:  PubMed          Journal:  J Exp Clin Cancer Res        ISSN: 0392-9078


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Correction to: J Exp Clin Cancer Res 36, 147 (2017) https://doi.org/10.1186/s13046-017-0621-2 Following publication of the original article [1], the authors identified some minor errors in Fig. 3 and Fig. S3, specifically:
Fig. 3

Effects of ZNF671 overexpression on NPC cell viability and colony formation ability in vitro. a qPCR analysis of ZNF671 mRNA expression in CNE-2 and 5-8F cells stably overexpression ZNF671. b Western blotting analysis of ZNF671 expression in CNE-2 and 5-8F cells stably overexpression ZNF671. c-d The CCK-8 assay showed overexpression of ZNF671 reduced the viability of CNE2 (c) and 5-8F (d) cells. e The colony formation assay showed overexpression of ZNF671 suppressed colony-forming ability. All experiments were performed at least three times; data are mean ± SD. *P < 0.05, **P < 0.01 vs. control, Student’s t-test

Figure 3e: incorrect images were used for colony formation assay images for CNE2 Vector, CNE2 ZNF671 and 5-8F ZNF671 (top left, top right, and bottom right) Fig. S3a: incorrect images were used for migration assay images for CNE2 ZNF671 at both 0 h and 48 h (left panel, bottom row) Effects of ZNF671 overexpression on NPC cell viability and colony formation ability in vitro. a qPCR analysis of ZNF671 mRNA expression in CNE-2 and 5-8F cells stably overexpression ZNF671. b Western blotting analysis of ZNF671 expression in CNE-2 and 5-8F cells stably overexpression ZNF671. c-d The CCK-8 assay showed overexpression of ZNF671 reduced the viability of CNE2 (c) and 5-8F (d) cells. e The colony formation assay showed overexpression of ZNF671 suppressed colony-forming ability. All experiments were performed at least three times; data are mean ± SD. *P < 0.05, **P < 0.01 vs. control, Student’s t-test The corrected figures are given here. The corrections do not have any effect on the final conclusions of the paper. The original article has been corrected. Additional file 3 Fig. S3. ZNF671 has no effect on affect NPC migratory and invasive ability. (A) Migration ability was measured using a wound healing assay (200 ×) and (B) Transwell assay with Matrigel (200 ×) in CNE2 and SUNE1 cells with the vector or ZNF671 overexpression. Scale bar: 100 μm; data are mean ± SD. *P < 0.05, **P < 0.01 vs. control, Student’s t-test.
  1 in total

1.  Epigenetic mediated zinc finger protein 671 downregulation promotes cell proliferation and tumorigenicity in nasopharyngeal carcinoma by inhibiting cell cycle arrest.

Authors:  Jian Zhang; Xin Wen; Na Liu; Ying-Qin Li; Xin-Ran Tang; Ya-Qin Wang; Qing-Mei He; Xiao-Jing Yang; Pan-Pan Zhang; Jun Ma; Ying Sun
Journal:  J Exp Clin Cancer Res       Date:  2017-10-19
  1 in total

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