Literature DB >> 3490850

Hyaluronic acid is an endogenous inducer of interleukin-1 production by human monocytes and rabbit macrophages.

D Hiro, A Ito, K Matsuta, Y Mori.   

Abstract

When human peripheral monocytes and rabbit peritoneal macrophages were incubated with hyaluronic acid, the media were found to contain interleukin-1 (IL-1) activity and to stimulate collagenase production by rabbit fibroblasts. A digestion of hyaluronic acid by testicular hyaluronidase decreased the IL-1 inducing activity. Polymixin B, an inhibitor of endotoxin, did not exert any effect towards the action of hyaluronic acid. Hyaluronic acid also stimulated human polymorphonuclear leucocytes to produce IL-1 like activity. These results indicate that hyaluronic acid is an endogenous IL-1 inducer and may play important roles in the pathological and/or physiological changes of connective tissues.

Entities:  

Mesh：

Substances：

Year:  1986        PMID： 3490850     DOI： 10.1016/0006-291x(86)90790-4

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  17 in total

1.  Hyaluronan is required for generation of hematopoietic cells during differentiation of human embryonic stem cells.

Authors:  Ingrid U Schraufstatter; Naira Serobyan; Jeanne Loring; Sophia K Khaldoyanidi
Journal:  J Stem Cells       Date:  2010

2.  Increased interleukin 1 beta production of macrophages by proteoglycan fragments deriving from articular cartilage in vitro.

Authors:  E Gurr; A Ahrens; G Lonnemann; A Delbrück
Journal:  Agents Actions       Date:  1990-01

3.  Regulation of human lung fibroblast glycosaminoglycan production by recombinant interferons, tumor necrosis factor, and lymphotoxin.

Authors:  J A Elias; R C Krol; B Freundlich; P M Sampson
Journal:  J Clin Invest       Date:  1988-02       Impact factor: 14.808

4.  Expression of CD44 variants in human inflammatory synovitis.

Authors:  L P Hale; B F Haynes; S S McCachren
Journal:  J Clin Immunol       Date:  1995-11       Impact factor: 8.317

5.  Hyaluronan inhibits postchemotherapy tumor regrowth in a colon carcinoma xenograft model.

Authors:  Barbara M Mueller; Ingrid U Schraufstatter; Valentina Goncharova; Tatiana Povaliy; Richard DiScipio; Sophia K Khaldoyanidi
Journal:  Mol Cancer Ther       Date:  2010-09-10       Impact factor: 6.261

6.  Autocrine effects of interleukin-6 mediate acute-phase proinflammatory and tissue-reparative transcriptional responses of canine bladder mucosa.

Authors:  Michael W Wood; Edward B Breitschwerdt; Jody L Gookin
Journal:  Infect Immun       Date:  2010-11-29       Impact factor: 3.441

Review 7.  Pneumococcal virulence factors: structure and function.

Authors:  M J Jedrzejas
Journal:  Microbiol Mol Biol Rev       Date:  2001-06       Impact factor: 11.056

8.  Nutraceutical augmentation of circulating endothelial progenitor cells and hematopoietic stem cells in human subjects.

Authors:  Nina A Mikirova; James A Jackson; Ron Hunninghake; Julian Kenyon; Kyle W H Chan; Cathy A Swindlehurst; Boris Minev; Amit N Patel; Michael P Murphy; Leonard Smith; Famela Ramos; Thomas E Ichim; Neil H Riordan
Journal:  J Transl Med       Date:  2010-04-08       Impact factor: 5.531

9.  Cytokine regulation of human lung fibroblast hyaluronan (hyaluronic acid) production. Evidence for cytokine-regulated hyaluronan (hyaluronic acid) degradation and human lung fibroblast-derived hyaluronidase.

Authors:  P M Sampson; C L Rochester; B Freundlich; J A Elias
Journal:  J Clin Invest       Date:  1992-10       Impact factor: 14.808

10.  Hyaluronan and CD44 in psoriatic skin. Intense staining for hyaluronan on dermal capillary loops and reduced expression of CD44 and hyaluronan in keratinocyte-leukocyte interfaces.

Authors:  R Tammi; K Paukkonen; C Wang; M Horsmanheimo; M Tammi
Journal:  Arch Dermatol Res       Date:  1994       Impact factor: 3.017
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.