Literature DB >> 34907509

Generation and Hematopoietic Differentiation of Mesenchymal Stromal/Stem Cell-Derived Induced Pluripotent Stem Cell Lines for Disease Modeling of Hematopoietic and Immunological Diseases.

Gülen Güney-Esken1, Fatima Aerts-Kaya2,3.   

Abstract

Here, we describe a protocol for reprogramming of bone marrow-derived multipotent mesenchymal stromal/stem cells to obtain induced pluripotent stem cells from patients with primary immune deficiencies using lentiviral vectors, followed by hematopoietic differentiation of the MSC-derived iPSCs. This protocol is particularly helpful in cases where it is difficult to obtain sufficient numbers of hematopoietic cells for research and can be applied to model any hematological/immunological disease.
© 2021. Springer Science+Business Media, LLC.

Entities:  

Keywords:  Differentiation; Hematopoiesis; Hematopoietic stem cells; Induced pluripotent stem cells; Mesenchymal stem cells

Mesh：

Year:  2022        PMID： 34907509     DOI： 10.1007/7651_2021_452

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN： 1064-3745


  15 in total

1.  Mesenchymal stem cells from adult bone marrow.

Authors:  Mark F Pittenger
Journal:  Methods Mol Biol       Date:  2008

2.  Early versus delayed diagnosis of SCID: triumph versus tragedy.

Authors:  Sarah Nicholas; Robert A Krance; I Celine Hanson; Javier Chinen; Robert J Mamlok; Chaim M Roifman; William T Shearer
Journal:  Clin Immunol       Date:  2011-04-14       Impact factor: 3.969

Review 3.  Induced pluripotent stem cells and severe combined immunodeficiency: merely disease modeling or potentially a novel cure?

Authors:  Harald Mikkers; Karin Pike-Overzet; Frank J T Staal
Journal:  Pediatr Res       Date:  2012-02-08       Impact factor: 3.756

4.  Modeling altered T-cell development with induced pluripotent stem cells from patients with RAG1-dependent immune deficiencies.

Authors:  Patrick M Brauer; Itai M Pessach; Erik Clarke; Jared H Rowe; Lisa Ott de Bruin; Yu Nee Lee; Carmen Dominguez-Brauer; Anne M Comeau; Geneve Awong; Kerstin Felgentreff; Yuhang H Zhang; Andrea Bredemeyer; Waleed Al-Herz; Likun Du; Francesca Ververs; Marion Kennedy; Silvia Giliani; Gordon Keller; Barry P Sleckman; David G Schatz; Frederic D Bushman; Luigi D Notarangelo; Juan Carlos Zúñiga-Pflücker
Journal:  Blood       Date:  2016-06-14       Impact factor: 22.113

5.  Lymphoid regeneration from gene-corrected SCID-X1 subject-derived iPSCs.

Authors:  Tushar Menon; Amy L Firth; Deirdre D Scripture-Adams; Zoran Galic; Susan J Qualls; William B Gilmore; Eugene Ke; Oded Singer; Leif S Anderson; Alexander R Bornzin; Ian E Alexander; Jerome A Zack; Inder M Verma
Journal:  Cell Stem Cell       Date:  2015-03-12       Impact factor: 24.633

Review 6.  Stem cell self-renewal: lessons from bone marrow, gut and iPS toward clinical applications.

Authors:  F J T Staal; C Baum; C Cowan; E Dzierzak; S Hacein-Bey-Abina; S Karlsson; T Lapidot; I Lemischka; S Mendez-Ferrer; H Mikkers; K Moore; E Moreno; C L Mummery; C Robin; T Suda; M Van Pel; G Vanden Brink; J J Zwaginga; W E Fibbe
Journal:  Leukemia       Date:  2011-04-29       Impact factor: 11.528

7.  Modeling Human Severe Combined Immunodeficiency and Correction by CRISPR/Cas9-Enhanced Gene Targeting.

Authors:  Chia-Wei Chang; Yi-Shin Lai; Erik Westin; Alireza Khodadadi-Jamayran; Kevin M Pawlik; Lawrence S Lamb; Frederick D Goldman; Tim M Townes
Journal:  Cell Rep       Date:  2015-08-28       Impact factor: 9.423

8.  Induction of pluripotent stem cells from adult human fibroblasts by defined factors.

Authors:  Kazutoshi Takahashi; Koji Tanabe; Mari Ohnuki; Megumi Narita; Tomoko Ichisaka; Kiichiro Tomoda; Shinya Yamanaka
Journal:  Cell       Date:  2007-11-30       Impact factor: 41.582

9.  Disease-specific induced pluripotent stem cells.

Authors:  In-Hyun Park; Natasha Arora; Hongguang Huo; Nimet Maherali; Tim Ahfeldt; Akiko Shimamura; M William Lensch; Chad Cowan; Konrad Hochedlinger; George Q Daley
Journal:  Cell       Date:  2008-08-07       Impact factor: 41.582

10.  Development, characterization, and hematopoietic differentiation of Griscelli syndrome type 2 induced pluripotent stem cells.

Authors:  Gülen Güney-Esken; Özgür Doğuş Erol; Burcu Pervin; Gülben Gürhan Sevinç; Tamer Önder; Elif Bilgiç; Petek Korkusuz; Ayşen Günel-Özcan; Duygu Uçkan-Çetinkaya; Fatima Aerts-Kaya
Journal:  Stem Cell Res Ther       Date:  2021-05-13       Impact factor: 6.832
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