Literature DB >> 3490632

Administration of GM1 ganglioside restores the dopamine content in striatum after chronic treatment with MPTP.

M Hadjiconstantinou, Z L Rossetti, R C Paxton, N H Neff.   

Abstract

The dopamine (DA) content of the mouse striatum thirty days after treatment with MPTP is significantly reduced. GM1 ganglioside administration during the thirty day period results in a partial restoration of the striatal DA content.

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Year:  1986        PMID： 3490632     DOI： 10.1016/0028-3908(86)90206-6

Source DB:  PubMed          Journal:  Neuropharmacology        ISSN： 0028-3908            Impact factor:   5.250


  14 in total

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