Neuroimaging of pleasantness and unpleasantness induced by thermal stimuli.

Functional brain imaging techniques provide unique insight into the process of human thermal regulation and its associated hedonics. Similar neuroimaging techniques have predominantly focused on the neural characterization of thermal response separately from hedonics. In this instance, there is a gap in the understanding of hedonics related to regional brain activations. Responses to localized, thermal stimuli are yet to be characterized, but it would appear that thermoregulatory regions are widely distributed throughout the hemispheres of the human brain. The distributed nature of neural activations related to temperature responses is consistent with multiple related functions contributing to thermoregulation. Estimating hedonics of thermal stimulation includes a cognitive process that could potentially interfere with identifying activation specific to hedonics. A future challenge for brain imaging studies is to more accurately dissect the functional neuroanatomy of thermoregulation and related hedonics in hemispheric regions.