Literature DB >> 34900581

An unusual presentation, novel treatment with Meropenem PMMA beads and complications of Klebsiella osteomyelitis in a healthy adult- A case report.

Kumar Amerendra Singh1, Chaitan Jaunky1, Hitesh Shah1.   

Abstract

Osteomyelitis caused by Klebsiella Pneumoniae in a healthy adult person is rare. We present an unusual case of Klebsiella Pneumoniae osteomyelitis of both femurs in an immunocompetent adult. The infection was resistant to local debridement and got complicated with pathological fracture, ultimately leading to infected non-union. The challenges faced in the management of sequential complications while treating this atypical osteomyelitis are discussed. Unusual presentation of femur osteomyelitis due to Klebsiella pneumonia can happen in a healthy adult. The Meropenem PMMA beads can be valuable for treating Klebsiella osteomyelitis. Staged procedures might be helpful to improve the condition.
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Entities:  

Keywords:  Chronic osteomyelitis; Distraction osteogenesis; Klebsiella pneumoniae; Limb reconstruction system; Meropenem polymethylmethacrylate beads

Year:  2021        PMID: 34900581      PMCID: PMC8639460          DOI: 10.1016/j.jcot.2021.101719

Source DB:  PubMed          Journal:  J Clin Orthop Trauma        ISSN: 0976-5662


  7 in total

1.  Elution kinetics, antimicrobial activity, and mechanical properties of 11 different antibiotic loaded acrylic bone cement.

Authors:  Ruben Gálvez-López; Alejandro Peña-Monje; Ramón Antelo-Lorenzo; Juan Guardia-Olmedo; Juan Moliz; José Hernández-Quero; Jorge Parra-Ruiz
Journal:  Diagn Microbiol Infect Dis       Date:  2013-10-05       Impact factor: 2.803

Review 2.  Primary osteomyelitis caused by hypervirulent Klebsiella pneumoniae.

Authors:  Bonnie C Prokesch; Michael TeKippe; Jiwoong Kim; Prithvi Raj; Erin McElvania TeKippe; David E Greenberg
Journal:  Lancet Infect Dis       Date:  2016-07-09       Impact factor: 25.071

3.  Characteristics of bacteremia between community-acquired and nosocomial Klebsiella pneumoniae infection: risk factor for mortality and the impact of capsular serotypes as a herald for community-acquired infection.

Authors:  Ren-Wen Tsay; L K Siu; Chang-Phone Fung; Feng-Yee Chang
Journal:  Arch Intern Med       Date:  2002-05-13

4.  Pyogenic vertebral osteomyelitis in heroin addicts.

Authors:  R S Fishbach; J E Rosenblatt; J G Dahlgren
Journal:  Calif Med       Date:  1973-08

Review 5.  Klebsiella spp. as nosocomial pathogens: epidemiology, taxonomy, typing methods, and pathogenicity factors.

Authors:  R Podschun; U Ullmann
Journal:  Clin Microbiol Rev       Date:  1998-10       Impact factor: 26.132

6.  A novel virulence gene in Klebsiella pneumoniae strains causing primary liver abscess and septic metastatic complications.

Authors:  Chi-Tai Fang; Yi-Ping Chuang; Chia-Tung Shun; Shan-Chwen Chang; Jin-Town Wang
Journal:  J Exp Med       Date:  2004-03-01       Impact factor: 14.307

7.  Bilateral osteomyelitis and liver abscess caused by hypervirulent Klebsiella pneumoniae- a rare clinical manifestation (case report).

Authors:  Emma Sturm; Alex Tai; Belinda Lin; Jason Kwong; Eugene Athan; Benjamin P Howden; Richard D Angliss; Rafik Asaid; James Pollard
Journal:  BMC Infect Dis       Date:  2018-08-07       Impact factor: 3.090

  7 in total

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