Literature DB >> 34896084

Partial dust removal in vehicles does not mitigate human exposure to organophosphate esters.

Aalekhya Reddam1, Nicholas Herkert2, Heather M Stapleton2, David C Volz3.   

Abstract

Organophosphate esters (OPEs) have been detected within car interior dust, suggesting that the indoor microenvironment of vehicles may represent a potential route of human exposure to OPEs. We recently showed that people with longer commutes are exposed to higher concentrations of tris(1,3-dichloro-2-isopropyl)phosphate (TDCIPP) - a widely used OPE - and other studies have suggested that dust removal may lead to lower exposure to chemicals. Therefore, the overall objective of this study was to determine if a decrease in interior car dust results in mitigation of personal OPE exposure. Participants (N = 49) were asked to wear silicone wristbands, and a subset of them wiped interior parts at the front of their vehicles prior to one study week (N = 25) or both study weeks (N = 11). There were no significant differences in total OPE concentrations (77.79-13,660 ng/g) nor individual OPE concentrations (0.04-4852.81 ng/g) across the different wiping groups nor in relation to participant residence ZIP codes and AC/Heater usage. These findings suggest that higher exposure to TDCIPP for participants with longer commutes may be independent of dust located on interior parts at the front of the vehicle. Therefore, our study demonstrates that there is a need for research on the potential contribution of other sources of TDCIPP exposure within car interiors.
Copyright © 2021 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Car interiors; Dust; Organophosphate esters; Silicone wristband; TDCIPP

Mesh:

Substances:

Year:  2021        PMID: 34896084      PMCID: PMC8760154          DOI: 10.1016/j.envres.2021.112525

Source DB:  PubMed          Journal:  Environ Res        ISSN: 0013-9351            Impact factor:   6.498


  40 in total

1.  Young children's exposure to phenols in the home: Associations between house dust, hand wipes, silicone wristbands, and urinary biomarkers.

Authors:  Jessica L Levasseur; Stephanie C Hammel; Kate Hoffman; Allison L Phillips; Sharon Zhang; Xiaoyun Ye; Antonia M Calafat; Thomas F Webster; Heather M Stapleton
Journal:  Environ Int       Date:  2020-12-17       Impact factor: 9.621

2.  Levels and profiles of organochlorines and flame retardants in car and house dust from Kuwait and Pakistan: implication for human exposure via dust ingestion.

Authors:  Nadeem Ali; Lulwa Ali; Toufeer Mehdi; Alin C Dirtu; Fatema Al-Shammari; Hugo Neels; Adrian Covaci
Journal:  Environ Int       Date:  2013-03-21       Impact factor: 9.621

3.  Aryl phosphate esters within a major PentaBDE replacement product induce cardiotoxicity in developing zebrafish embryos: potential role of the aryl hydrocarbon receptor.

Authors:  Sean P McGee; Alex Konstantinov; Heather M Stapleton; David C Volz
Journal:  Toxicol Sci       Date:  2013-02-01       Impact factor: 4.849

4.  Neurotoxicological and thyroid evaluations of rats developmentally exposed to tris(1,3-dichloro-2-propyl)phosphate (TDCIPP) and tris(2-chloro-2-ethyl)phosphate (TCEP).

Authors:  Virginia C Moser; Pamela M Phillips; Joan M Hedge; Katherine L McDaniel
Journal:  Neurotoxicol Teratol       Date:  2015-08-20       Impact factor: 3.763

5.  Biomarkers of inflammation in ozone-exposed humans. Comparison of the nasal and bronchoalveolar lavage.

Authors:  D E Graham; H S Koren
Journal:  Am Rev Respir Dis       Date:  1990-07

6.  Concentrations of brominated flame retardants in dust from United Kingdom cars, homes, and offices: causes of variability and implications for human exposure.

Authors:  Harrad Stuart; Catalina Ibarra; Mohamed Abou-Elwafa Abdallah; Rachel Boon; Hugo Neels; Adrian Covaci
Journal:  Environ Int       Date:  2008-06-16       Impact factor: 9.621

7.  Variations in amounts and potential sources of volatile organic chemicals in new cars.

Authors:  Yeh-Chung Chien
Journal:  Sci Total Environ       Date:  2007-05-30       Impact factor: 7.963

8.  Semi-Volatile Organic Compounds in Car Dust: A Pilot Study in Jeddah, Saudi Arabia.

Authors:  Nadeem Ali; Mohammad W Kadi; Hussain Mohammed Salem Ali Albar; Muhammad Imtiaz Rashid; Sivaraman Chandrasekaran; Ahmed Saleh Summan; Cynthia A de Wit; Govindan Malarvannan
Journal:  Int J Environ Res Public Health       Date:  2021-04-30       Impact factor: 3.390

Review 9.  Indoor Air Pollution in Cars: An Update on Novel Insights.

Authors:  Nicole Zulauf; Janis Dröge; Doris Klingelhöfer; Markus Braun; Gerhard M Oremek; David A Groneberg
Journal:  Int J Environ Res Public Health       Date:  2019-07-09       Impact factor: 3.390

10.  Novel and high volume use flame retardants in US couches reflective of the 2005 PentaBDE phase out.

Authors:  Heather M Stapleton; Smriti Sharma; Gordon Getzinger; P Lee Ferguson; Michelle Gabriel; Thomas F Webster; Arlene Blum
Journal:  Environ Sci Technol       Date:  2012-11-28       Impact factor: 9.028

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