Literature DB >> 34895501

Anti-Cas9 immunity: A formidable challenge for muscle genome editing.

William R Lagor1.   

Abstract

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Year:  2021        PMID： 34895501      PMCID： PMC8753515          DOI： 10.1016/j.ymthe.2021.12.006

Source DB:  PubMed          Journal:  Mol Ther        ISSN： 1525-0016            Impact factor:   11.454


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  10 in total

1.  Identification of preexisting adaptive immunity to Cas9 proteins in humans.

Authors:  Carsten T Charlesworth; Priyanka S Deshpande; Daniel P Dever; Joab Camarena; Viktor T Lemgart; M Kyle Cromer; Christopher A Vakulskas; Michael A Collingwood; Liyang Zhang; Nicole M Bode; Mark A Behlke; Beruh Dejene; Brandon Cieniewicz; Rosa Romano; Benjamin J Lesch; Natalia Gomez-Ospina; Sruthi Mantri; Mara Pavel-Dinu; Kenneth I Weinberg; Matthew H Porteus
Journal:  Nat Med       Date:  2019-01-28       Impact factor: 53.440

2.  Postnatal genome editing partially restores dystrophin expression in a mouse model of muscular dystrophy.

Authors:  Chengzu Long; Leonela Amoasii; Alex A Mireault; John R McAnally; Hui Li; Efrain Sanchez-Ortiz; Samadrita Bhattacharyya; John M Shelton; Rhonda Bassel-Duby; Eric N Olson
Journal:  Science       Date:  2015-12-31       Impact factor: 47.728

3.  In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy.

Authors:  Christopher E Nelson; Chady H Hakim; David G Ousterout; Pratiksha I Thakore; Eirik A Moreb; Ruth M Castellanos Rivera; Sarina Madhavan; Xiufang Pan; F Ann Ran; Winston X Yan; Aravind Asokan; Feng Zhang; Dongsheng Duan; Charles A Gersbach
Journal:  Science       Date:  2015-12-31       Impact factor: 47.728

4.  In vivo gene editing in dystrophic mouse muscle and muscle stem cells.

Authors:  Mohammadsharif Tabebordbar; Kexian Zhu; Jason K W Cheng; Wei Leong Chew; Jeffrey J Widrick; Winston X Yan; Claire Maesner; Elizabeth Y Wu; Ru Xiao; F Ann Ran; Le Cong; Feng Zhang; Luk H Vandenberghe; George M Church; Amy J Wagers
Journal:  Science       Date:  2015-12-31       Impact factor: 47.728

5.  A multifunctional AAV-CRISPR-Cas9 and its host response.

Authors:  Wei Leong Chew; Mohammadsharif Tabebordbar; Jason K W Cheng; Prashant Mali; Elizabeth Y Wu; Alex H M Ng; Kexian Zhu; Amy J Wagers; George M Church
Journal:  Nat Methods       Date:  2016-09-05       Impact factor: 28.547

6.  High prevalence of Streptococcus pyogenes Cas9-reactive T cells within the adult human population.

Authors:  Dimitrios L Wagner; Leila Amini; Desiree J Wendering; Lisa-Marie Burkhardt; Levent Akyüz; Petra Reinke; Hans-Dieter Volk; Michael Schmueck-Henneresse
Journal:  Nat Med       Date:  2018-10-29       Impact factor: 53.440

7.  Gene editing restores dystrophin expression in a canine model of Duchenne muscular dystrophy.

Authors:  Leonela Amoasii; John C W Hildyard; Hui Li; Efrain Sanchez-Ortiz; Alex Mireault; Daniel Caballero; Rachel Harron; Thaleia-Rengina Stathopoulou; Claire Massey; John M Shelton; Rhonda Bassel-Duby; Richard J Piercy; Eric N Olson
Journal:  Science       Date:  2018-08-30       Impact factor: 47.728

8.  Somatic gene editing ameliorates skeletal and cardiac muscle failure in pig and human models of Duchenne muscular dystrophy.

Authors:  A Moretti; L Fonteyne; F Giesert; P Hoppmann; A B Meier; T Bozoglu; A Baehr; C M Schneider; D Sinnecker; K Klett; T Fröhlich; F Abdel Rahman; T Haufe; S Sun; V Jurisch; B Kessler; R Hinkel; R Dirschinger; E Martens; C Jilek; A Graf; S Krebs; G Santamaria; M Kurome; V Zakhartchenko; B Campbell; K Voelse; A Wolf; T Ziegler; S Reichert; S Lee; F Flenkenthaler; T Dorn; I Jeremias; H Blum; A Dendorfer; A Schnieke; S Krause; M C Walter; N Klymiuk; K L Laugwitz; E Wolf; W Wurst; C Kupatt
Journal:  Nat Med       Date:  2020-01-27       Impact factor: 53.440

9.  AAV-CRISPR Gene Editing Is Negated by Pre-existing Immunity to Cas9.

Authors:  Ang Li; Mark R Tanner; Ciaran M Lee; Ayrea E Hurley; Marco De Giorgi; Kelsey E Jarrett; Timothy H Davis; Alexandria M Doerfler; Gang Bao; Christine Beeton; William R Lagor
Journal:  Mol Ther       Date:  2020-04-19       Impact factor: 11.454

10.  Cas9-specific immune responses compromise local and systemic AAV CRISPR therapy in multiple dystrophic canine models.

Authors:  Sandeep R P Kumar; Dennis O Pérez-López; Chady H Hakim; Nalinda B Wasala; Dong Zhang; Yongping Yue; James Teixeira; Xiufang Pan; Keqing Zhang; Emily D Million; Christopher E Nelson; Samantha Metzger; Jin Han; Jacqueline A Louderman; Florian Schmidt; Feng Feng; Dirk Grimm; Bruce F Smith; Gang Yao; N Nora Yang; Charles A Gersbach; Shi-Jie Chen; Roland W Herzog; Dongsheng Duan
Journal:  Nat Commun       Date:  2021-11-24       Impact factor: 17.694
  10 in total

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