| Literature DB >> 3489147 |
Abstract
A simplified, less expensive cryopreservation technique for parathyroid tissue was examined in animal study and on human tissue in vitro. More than 3/4 of all replantations in the rat were successful after cryopreservation. After replantation of one single gland only 1/3 of all animals attained normal parathyroid function. This fact shows the importance of the quantity of transplanted viable tissue. Viability of human parathyroid tissue after cryopreservation was 80-90%. The PTH-production of human parathyroid tissue in vitro after cryopreservation and the suppressibility in different calcium concentrations were similar to normal fresh tissue. All our results prove a good functioning of this simplified cryopreservation method.Entities:
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Year: 1986 PMID: 3489147 DOI: 10.1007/BF01263403
Source DB: PubMed Journal: Langenbecks Arch Chir ISSN: 0023-8236