Literature DB >> 3489104

Crystal structure determination, refinement and the molecular model of the alpha-amylase inhibitor Hoe-467A.

J W Pflugrath, G Wiegand, R Huber, L Vértesy.   

Abstract

The crystal and molecular structure of the alpha-amylase inhibitor Hoe-467A has been determined and refined at high resolution. The polypeptide chain is folded in two triple-stranded sheets, which form a barrel. The topology of folding is as found in the immunoglobulin domains. The amino acid triplet Trp18-Arg19-Tyr20 has an exceptional conformation and position in the molecule and is possibly involved in inhibitory activity.

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Year:  1986        PMID: 3489104     DOI: 10.1016/0022-2836(86)90520-6

Source DB:  PubMed          Journal:  J Mol Biol        ISSN: 0022-2836            Impact factor:   5.469


  22 in total

1.  Unfolding proteins by external forces and temperature: the importance of topology and energetics.

Authors:  E Paci; M Karplus
Journal:  Proc Natl Acad Sci U S A       Date:  2000-06-06       Impact factor: 11.205

2.  Conformational disorder of proteins assessed by real-space molecular dynamics refinement.

Authors:  Z Chen; M S Chapman
Journal:  Biophys J       Date:  2001-03       Impact factor: 4.033

3.  Templating α-amylase peptide inhibitors with organotin compounds.

Authors:  Fernando Porcelli; Cristina Olivieri; Larry R Masterson; Yi Wang; Gianluigi Veglia
Journal:  J Biol Inorg Chem       Date:  2011-07-07       Impact factor: 3.358

4.  Cross-validated maximum likelihood enhances crystallographic simulated annealing refinement.

Authors:  P D Adams; N S Pannu; R J Read; A T Brünger
Journal:  Proc Natl Acad Sci U S A       Date:  1997-05-13       Impact factor: 11.205

5.  Heterologous expression of the alpha-amylase inhibitor gene cloned from an amplified genomic sequence of Streptomyces tendae.

Authors:  K P Koller; G Riess
Journal:  J Bacteriol       Date:  1989-09       Impact factor: 3.490

6.  Denaturant-induced movement of the transition state of protein folding revealed by high-pressure stopped-flow measurements.

Authors:  G Pappenberger; C Saudan; M Becker; A E Merbach; T Kiefhaber
Journal:  Proc Natl Acad Sci U S A       Date:  2000-01-04       Impact factor: 11.205

7.  CDC14A phosphatase is essential for hearing and male fertility in mouse and human.

Authors:  Ayesha Imtiaz; Inna A Belyantseva; Alisha J Beirl; Cristina Fenollar-Ferrer; Rasheeda Bashir; Ihtisham Bukhari; Amal Bouzid; Uzma Shaukat; Hela Azaiez; Kevin T Booth; Kimia Kahrizi; Hossein Najmabadi; Azra Maqsood; Elizabeth A Wilson; Tracy S Fitzgerald; Abdelaziz Tlili; Rafal Olszewski; Merete Lund; Taimur Chaudhry; Atteeq U Rehman; Matthew F Starost; Ali M Waryah; Michael Hoa; Lijin Dong; Robert J Morell; Richard J H Smith; Sheikh Riazuddin; Saber Masmoudi; Katie S Kindt; Sadaf Naz; Thomas B Friedman
Journal:  Hum Mol Genet       Date:  2018-03-01       Impact factor: 6.150

8.  Effects of disulfide bonds on folding behavior and mechanism of the beta-sheet protein tendamistat.

Authors:  Meng Qin; Jian Zhang; Wei Wang
Journal:  Biophys J       Date:  2005-10-07       Impact factor: 4.033

9.  Nucleotide sequence and expression of a Streptomyces griseosporeus proteinaceous alpha-amylase inhibitor (HaimII) gene.

Authors:  H Nagaso; S Saito; H Saito; H Takahashi
Journal:  J Bacteriol       Date:  1988-10       Impact factor: 3.490

10.  Arginine is essential for the alpha-amylase inhibitory activity of the alpha-amylase/subtilisin inhibitor (BASI) from barley seeds.

Authors:  J Abe; U Sidenius; B Svensson
Journal:  Biochem J       Date:  1993-07-01       Impact factor: 3.857

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