Literature DB >> 3488984

New class I in man: serological and molecular characterization.

R Fauchet, M Boscher, O Bouhallier, G Merdrignac, B Genetet, P Turmel, D J Charron.   

Abstract

New class I antigens in linkage disequilibrium with HLA-A antigen are demonstrated in PHA T and EBV preferential target cells using human alloantisera. These new antigens are defined as class I antigens by immunoprecipitation of a 41-12 k dimer. The molecule is shown to be distinct from the HLA-A, -B, -C molecule and in particular from the A3 molecule as in sequential immunoprecipitations, the depletion of the HLA-A, -B, -C molecule or A3 molecule (44-12 k) has no effect on the new molecule (41-12 k). Being present on the PHA T cells and lymphoblast lines, these antigens are considered as new epitopes involved in the the cell activation process.

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Year:  1986        PMID： 3488984     DOI： 10.1016/0198-8859(86)90069-8

Source DB:  PubMed          Journal:  Hum Immunol        ISSN： 0198-8859            Impact factor:   2.850


  5 in total

Review 1.  Organization of the human class I major histocompatibility complex genes.

Authors:  B H Koller; D Geraghty; H T Orr; Y Shimizu; R DeMars
Journal:  Immunol Res       Date:  1987       Impact factor: 2.829

2.  Isolation of a human major histocompatibility complex class I gene encoding a nonubiquitous molecule expressed on activated lymphocytes.

Authors:  P Paul; R Fauchet; M Y Boscher; B Sayagh; M Masset; G Medrignac; J Dausset; D Cohen
Journal:  Proc Natl Acad Sci U S A       Date:  1987-05       Impact factor: 11.205

3.  Activated human T lymphocytes express MHC class I heavy chains not associated with beta 2-microglobulin.

Authors:  E Schnabl; H Stockinger; O Majdic; H Gaugitsch; I J Lindley; D Maurer; A Hajek-Rosenmayr; W Knapp
Journal:  J Exp Med       Date:  1990-05-01       Impact factor: 14.307

4.  Transfer and expression of three cloned human non-HLA-A,B,C class I major histocompatibility complex genes in mutant lymphoblastoid cells.

Authors:  Y Shimizu; D E Geraghty; B H Koller; H T Orr; R DeMars
Journal:  Proc Natl Acad Sci U S A       Date:  1988-01       Impact factor: 11.205

5.  Molecular definition of a polymorphic antigen (LA45) of free HLA-A and -B heavy chains found on the surfaces of activated B and T cells.

Authors:  J A Madrigal; M P Belich; R J Benjamin; A M Little; W H Hildebrand; D L Mann; P Parham
Journal:  J Exp Med       Date:  1991-11-01       Impact factor: 14.307
  5 in total

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