Literature DB >> 34887227

[Costs of intravenous vs. subcutaneous administration of trastuzumab in peruvian patients with HER2-positive breast cancer - An observational analysis of direct and indirect costs].

Henry Olivera Changra1, José Fernando Robles Díaz2.   

Abstract

ANTECEDENT AND
OBJECTIVE: In Peru, the presentation of TZM-IV and TZM-SC is carried out. But there is no comparative cost data by route of administration. The objective of our study was to know the costs of patients with breast cancer, comparing the routes of administration in a regional cancer center in Peru.
MATERIAL AND METHODS: In 2020, patients who were prescribed TZM treatment were prospectively recorded clinical, demographic and transport data, and medical costs were obtained from medical history and pharmacy records. With these data, the simulation was performed in 100 patients who received 18 cycles of the drug.
RESULTS: The main contributor to the cost of the difference was the cost of the drug itself, being S/. 4,711.11 (1,323.35 USD) and S/. 4,680.30 (1,314.69 USD) for TZM-IV and TZM-SC, respectively. The administration costs to treat 100 patients with complete cycles of TZM-IV and TZM-SC were S/. 334,488.53 (93,957.45 USD) and S/.207,455.33 (58,873.97 USD), respectively. Indirect costs indicate that patients lost in total, S/. 1,123.28 (315.53 USD) and S/. 1,148.60 (322.64 USD) in TZM-IV and TZMSC per patient, respectively.
CONCLUSIONS: The use of TZM-SC is recommended, in the scenario of a lower cost of the drug and a shorter duration of administration time. Especially in a country with low funding, which only allows subsidizing the direct costs of cancer treatment.
Copyright © 2021 FECA. Publicado por Elsevier España, S.L.U. All rights reserved.

Entities:  

Keywords:  Breast neoplasia; Costos y análisis de costos; Costs and cost analysis; Health resources; Neoplasia mamaria; Recursos de salud; Trastuzumab

Mesh:

Substances:

Year:  2021        PMID: 34887227     DOI: 10.1016/j.jhqr.2021.10.008

Source DB:  PubMed          Journal:  J Healthc Qual Res        ISSN: 2603-6479


  2 in total

1.  Gastric collision tumour with probable ectopic pancreatic origin.

Authors:  Juan Francisco Olivos Gonzáles; Rodrigo Arroyo-Gárate; Miguel Angel Leon Estrella; Gustavo Cerrillo; Stefanie Campos Medinae
Journal:  Ecancermedicalscience       Date:  2022-06-13

2.  Cost analysis of total neoadjuvant therapy with 5 × 5 Gy radiation therapy versus conventional chemoradiotherapy for locally advanced rectal cancer among Peruvians.

Authors:  José Fernando Robles Díaz; Henry Olivera Changra
Journal:  Ecancermedicalscience       Date:  2022-06-07
  2 in total

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