| Literature DB >> 34886293 |
Mingyu Sun1, Leizi Min2, Na Xu1, Lei Huang3, Xuemei Li1.
Abstract
Exercise intervention has a positive effect on reducing the fall risk in older adults. To investigate the effect of different factors of exercise intervention (type, duration, and frequency) on reducing the fall risk in older adults, a meta-analysis was performed in this study. According to the PRISMA®, two researchers independently searched PubMed, Web of Science, and the China National Knowledge Infrastructure databases to assess the quality of the studies using the PEDro scale. A total of 648 subjects in 10 randomized controlled trials were included in this study, and the exercise interventions included integrated training (resistance training, core training, and balance training), balance training, core training, Pilates, Ba Duan Jin, and Tai Chi. These studies show that exercise intervention has a huge and significant impact on reducing the risk of falls of the elderly. In conclusion, an integrated intervention with a frequency of more than five times a week and a duration of more than 32 weeks are more effective in reducing the fall risk.Entities:
Keywords: exercise intervention; fall risk; meta-analysis; older adults
Mesh:
Year: 2021 PMID: 34886293 PMCID: PMC8657315 DOI: 10.3390/ijerph182312562
Source DB: PubMed Journal: Int J Environ Res Public Health ISSN: 1660-4601 Impact factor: 3.390
Inclusion criteria and exclusion criteria.
| Criteria | Type | Definition |
|---|---|---|
| Inclusion Criteria | Study type | Randomized controlled trial (RCT) studies in Chinese and English. |
| Study subject | Middle-aged and older adults (over 50 years old) without disabilities and other diseases that make them unsuitable for exercise interventions. | |
| Intervention requirement | Physical activity at baseline levels is the same in both groups, and the duration of the intervention is greater than or equal to 4 weeks. | |
| Outcome indicators | Fall risk index, fall risk score. | |
| Exclusion Criteria | Indicators without clear comparability. | |
| Baseline level data not available. | ||
| Missing full text or incomplete data on outcome indicators. |
Figure 1Screening process.
Characteristics of the included studies.
| Code | Publish Time | Country | intervention Programs | Exercise Intervention Type | Participant Type | Age | Gender | Test Group Size | Control Group Size | PEDro Score | Literature Quality |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Guo et al. (2020) [ | 2020 | China | Exercise includes weight-bearing exercise, balance training and muscle training. Weight-bearing exercises are carried out 3 times a day, 20 min each time. Balance exercise can improve balance ability, which is carried out 3 times a day, 20 min each time. | Integrated training (weight training, balance training, and muscle training) | Older adults with osteoporosis | 62–80 | Mixed | 35 | 35 | 5 | Medium |
| Lipardo et al. (2020) [ | 2020 | Philippines | 12 consecutive weeks, 3 sessions per week, 60 to 90 min of physical training | Physical training | Older adults in the community with mild cognitive impairment | 60–83 | Mixed | 23 | 23 | 5 | Medium |
| Roller et al. (2017) [ | 2018 | United States | Subjects in the Pilates group attended 8 × 10³sessions of a 45-min Pilates exercise program using a Reformer once a week over a 10-week period | Pilates | Older adults over 65 years old with a history of falls in the past year | 65–95 | Mixed | 27 | 28 | 7 | High |
| Sousa et al. (2016a) [ | 2016 | Portugal | The aerobic exercise group trained twice per week in a land environment (Mondays and Wednesdays) and once per week in an aquatic environment (Fridays). All aerobic training sessions consisted of: (i) a 10-min warm-up period, which included walking and flexibility exercises; (ii)a 30-min cardiorespiratory period, including walking and/or brisk walking; (iii) a 10-min muscular endurance, which included three exercises (three sets of 15–20 repetitions) using only bodyweight and gravity for strengthening the lower and upper limbs in a land environment, and water resistance in an aquatic environment; and (iv) a 5-min cool-down period, which included breathing and stretching exercises. | Aerobic exercise | Older men in the community | 65–74 | Male | 22 | 22 | 6 | Medium |
| Sousa et al. (2016b) [ | 2016 | Portugal | the aerobic training session on Mondays were replaced by a resistance exercise session. The intensity of the resistance training sessions was defined by the pyramidal method set to 65% of 1-RM in the first eight weeks; 75% of 1-RM for Weeks 8–24; 70% of 1-RM for Weeks 24–28; and 65% of 1-RM for Weeks 28–32 (three sets of 10–12 repetitions in all sessions). Each session always began with a 10-min warm-up and ended with a cool-down period. The main part of the sessions consisted of a circuit of seven exercises: bench press, leg press, lateral pull-down, leg extension, military press, leg curl and arm curl, in this order, and carried out with conventional variable resistance devices (PANATTA, Fitline 2000 series, Italy). The 1-RM values were taken at the first workout of Week 1, Week 8, Week 16 and Week 24, and at the last workout of Week 32, allowing periodic adjustment of the resistance training intensity for the combined exercise group. | Integrated training (weight training, balance training, and muscle training) | Older men in the community | 65–74 | Male | 22 | 22 | 6 | Medium |
| Sungkarat et al. (2016) [ | 2017 | Thailand | Participants in the Tai Chi group attended Tai Chi classes led by a certified Tai Chi instructor for 3 weeks (9 sessions) to learn Tai Chi principles and the 10-form Tai Chi. The Tai Chi classes were held with six or seven persons per class in the exercise room at the Department of Physical Therapy. Participants then practiced Tai Chi at home three times per week for 12 weeks. | Tai chi | Older adults with mild cognitive impairment | 61–75 | Mixed | 33 | 33 | 6 | Medium |
| Wang et al. (2020) [ | 2020 | China | Exercise 5 times a week, time is 7:00–8:30 in the morning, each exercise time is 90 min, including 15 min of warm-up activities, 60 min of formal exercises, and 15 min of relaxation. | Diabolo training | Older adults in rural area | 60–72 | Female | 14 | 13 | 5 | Medium |
| Wu et al. (2017) [ | 2017 | China | Baduanjin exercises are performed 2 times a day, 3 times each time, and the treatment cycle is 30 days. The patient chooses appropriate actions for practice under the guidance of doctors according to their own conditions and individual differences | Ba Duan Jin | Older adults in the community | 65–80 | Mixed | 60 | 60 | 6 | Medium |
| Zhang et al. (2016) [ | 2016 | China | Training time is 45 min, training 5 days per week, and the intervention time is 8 weeks | Balance training | Older adults in the | 63–78 | Mixed | 60 | 60 | 6 | Medium |
| Zhuang et al. (2014) [ | 2014 | China | The intervention group received 60 min exercise classes three times per week for 12 weeks in the community center. The intensity of the exercise was increased gradually over time to help participants achieve success. Each class started with a 5-min warm-up, followed by 15 min of balance exercises, 15 min of muscle-strength training, 15 min of | Integrated training (muscle training, balance raining, and Tai Chi) | Older adults in the community | 60–80 | Mixed | 28 | 28 | 6 | Medium |
Characteristics of interventions and outcome indicators in the included studies.
| Code | Main Indicator | Outcome Indicator | Intervention Duration | Intervention Frequency | Result |
|---|---|---|---|---|---|
| Guo et al. (2020) [ | Comparison of disease efficacy, disease awareness, fall prevention awareness, psychological anxiety level, body immunity status, bone density before and after care, and incidence of falls between the two groups of older adults with osteoporosis. | Fall prevention awareness score | 1 year | Daily | Medication and exercise interventions have a better preventive effect on older adults. |
| Lipardo et al. (2020) [ | Assessment of fall incidence, overall fall risk, dynamic balance, walking speed, and lower-extremity strength. | PPA (Physiological Profile Assessment) test | 12 weeks | 3 times a week | No significant differences in fall rates and fall risk were found between the groups after the intervention. Physical training and cognitive training and the combination of them can improve dynamic balance. Further studies with larger sample sizes are needed to determine if the interventions are effective. |
| Roller et al. (2017) [ | SOT score of the NeuroCom® system, Timed Up and Go (TUG), and Activity Specific Balance Confidence (ABC) Scale. | SOT score | 10 weeks | Once a week | Pilates modified exercises once a week for 10 weeks can reduce the fall risk in adults aged 65 and older who are at risk of falls. This exercise significantly improved static and dynamic balance, functional mobility, balance self-efficacy, and lower-extremity AROM. In contrast, the control group showed no significant improvement in any of the indicators. Pilates modified exercises were more effective than no exercise intervention in improving AROM in the hip and ankle joints. |
| Sousa et al. (2016a) [ | Timed up test, functional reach (FR) test, CS-30 test, and 6-min walk test. | CS-30 test | 32 weeks | 3 times a week | The addition of resistance exercise to aerobic exercise may improve factors associated with increased fall risk. Both combined exercise and aerobic exercise are more effective than no exercise in reducing the fall risk. |
| Sousa et al. (2016b) [ | Timed up test, FR test, CS-30 test, and 6-min walk test. | CS-30 test | 32 weeks | 3 times a week | The addition of resistance exercise to aerobic exercise may improve factors associated with increased fall risk. Both combined exercise and aerobic exercise are more effective than no exercise in reducing the fall risk. |
| Sungkarat et al. (2016) [ | Fall risk index with physiological profile assessment (PPA). | PPA test | 12 weeks | 3 times a week | In older adults with multi-domain amnestic mild cognitive impairment, the combination of core training and Tai Chi three times a week for 15 weeks significantly improved cognitive function and modestly reduced the fall risk. In particular, Tai Chi may have quite great effects on reducing the fall risk. |
| Wang et al. (2020) [ | Static and dynamic balance ability test (Good Balance balance tester), CS-30 test, Tetrax fall risk test. | Tetrax fall risk index | 14 weeks | 5 times a week | The 14-week diabolo exercise strengthened the lower-extremity muscles of older adults, reducing the possibility of the fall risk and improving balance. Eight weeks of physical education and health lectures motivated older adults to take action, increasing their exercise frequencies. |
| Wu et al. (2017) [ | MFS, Berg balance scale score, “get-up-and-walk” timing test, self-rating anxiety scale, Riker SAS score, and the SF-36 health survey. | MFS | 30 days | Daily | Ba Duan Jin could effectively reduce the fall risk among older adults in the community to a certain extent. |
| Zhang et al. (2016) [ | Fall risk score | Fall risk score | 8 weeks | Daily | Balance training could reduce the fall risk in older adults. |
| Zhuang et al. (2014) [ | CS-30 test, TUG test, FR test, and star offset balance test (SEBT). | CS-30 test | 12 weeks | 3 times a week | This study provided an effective, evidence-based fall prevention program that can be implemented to improve the physical health of older adults in the community and reduce the fall risk. In the assessment of fall risk in older adults, the SEBT might be a sensitive measure of physical performance. |
Test for overall combined effect size.
| Model | Sample Size | Heterogeneity Test | Total Effect Size Test | SMD | 95% CI | ||
|---|---|---|---|---|---|---|---|
| I2 |
| Z |
| ||||
| Random-Effect Model | 10 | 92% | <0.00001 | 4.22 | <0.0001 | 1.4 | 0.75–2.05 |
I2: I squared statistic; Z: overall effect; SMD: standardized mean difference.
Figure 2The effect of exercise intervention on reducing the fall risk in older adults. Notes: The figure is automatically generated, the bold no meaning.
Figure 3Funnel plot of publication bias assessment.
Effect of different exercise interventions on reducing the fall risk in older adults.
| Type | No. of Studies | Test Group Size | Control Group Size | I2 | SMD | 95% CI |
|
|---|---|---|---|---|---|---|---|
| Integrated training | 3 | 85 | 85 | 95% | 3.16 | 1.12–5.21 | 0.002 |
| Physical training | 3 | 105 | 105 | 85% | 0.88 | 0.08–1.68 | 0.03 |
| Fitness training | 4 | 134 | 134 | 31% | 0.57 | 0.25–0.88 | 0.004 |
| Total | 10 | 324 | 324 | 92% | 1.4 | 0.75–2.05 | <0.0001 |
Figure 4Effect of different exercise interventions on reducing the fall risk in older adults. Notes: The figure is automatically generated, the bold no meaning.
Effect of different intervention durations on reducing the fall risk in older adults.
| Duration | No. of Studies | Test Group Size | Control Group Size | I2 | SMD | 95% CI |
|
|---|---|---|---|---|---|---|---|
| Less than 12 weeks | 3 | 147 | 148 | 77% | 0.68 | 0.17–1.20 | 0.009 |
| 12–32 weeks | 4 | 98 | 97 | 88% | 0.98 | 0.06–1.89 | 0.04 |
| More than 32 weeks | 4 | 79 | 79 | 96% | 2.92 | 0.69–5.15 | 0.01 |
| Total | 10 | 324 | 324 | 92% | 1.4 | 0.75–2.05 | <0.0001 |
Figure 5Effect of different intervention durations on reducing the fall risk in older adults. Notes: The figure is automatically generated, the bold no meaning.
Effect of different intervention frequencies on reducing the fall risk in older adults.
| Frequency | No. of Studies | Test Group Size | Control Group Size | I2 | SMD | 95% CI |
|
|---|---|---|---|---|---|---|---|
| 1–2 times a week | 1 | 27 | 27 | - | 0.22 | −0.31–0.75 | 0.42 |
| 3–5 times a week | 6 | 142 | 141 | 85% | 1.75 | 0.50–1.84 | 0.0006 |
| More than 5 times a week | 3 | 155 | 155 | 97% | 2.39 | 0.60–4.18 | 0.009 |
| Total | 10 | 324 | 324 | 92% | 1.4 | 0.75–2.05 | <0.0001 |
Figure 6Effect of different intervention frequencies on reducing the fall risk in older adults. Notes: The figure is automatically generated, the bold no meaning.