PURPOSE: The aim of the review study is investigation of the prognostic factors of the liver transplantation for hepatocellular carcinoma. METHODS: A literature review has been made, especially in countries where dominantly living donor liver transplantation is performed, such as Turkey. Liver transplantation from deceased donor and from living donor has been evaluated about as advantages and disadvantages, and their effects on prognosis have been compared. In addition, hepatocellular carcinoma series of Koç University Liver Transplantation center has been presented. RESULTS: Liver transplantation is still the best treatment option with 5-year 50% survival rate for hepatocellular carcinoma even in patient who has locally advanced tumor. The patient's survival is not only an important issue but also the living donor's safety is controversial particularly when expectation of recipient's 5-year survival is below 50% due to donor complication. CONCLUSION: Detailed preoperative examination, appropriate patient selection, and timing of surgery are seen the most important issues in liver transplant's patients with hepatocellular carcinoma.
PURPOSE: The aim of the review study is investigation of the prognostic factors of the liver transplantation for hepatocellular carcinoma. METHODS: A literature review has been made, especially in countries where dominantly living donor liver transplantation is performed, such as Turkey. Liver transplantation from deceased donor and from living donor has been evaluated about as advantages and disadvantages, and their effects on prognosis have been compared. In addition, hepatocellular carcinoma series of Koç University Liver Transplantation center has been presented. RESULTS: Liver transplantation is still the best treatment option with 5-year 50% survival rate for hepatocellular carcinoma even in patient who has locally advanced tumor. The patient's survival is not only an important issue but also the living donor's safety is controversial particularly when expectation of recipient's 5-year survival is below 50% due to donor complication. CONCLUSION: Detailed preoperative examination, appropriate patient selection, and timing of surgery are seen the most important issues in liver transplant's patients with hepatocellular carcinoma.
Authors: Julie K Heimbach; Laura M Kulik; Richard S Finn; Claude B Sirlin; Michael M Abecassis; Lewis R Roberts; Andrew X Zhu; M Hassan Murad; Jorge A Marrero Journal: Hepatology Date: 2018-01 Impact factor: 17.425
Authors: Arich R Reynolds; Alessandro Furlan; David T Fetzer; Eizaburo Sasatomi; Amir A Borhani; Matthew T Heller; Mitchell E Tublin Journal: Radiographics Date: 2015 Mar-Apr Impact factor: 5.333
Authors: Volkan Ince; Sami Akbulut; Emrah Otan; Veysel Ersan; Serdar Karakas; Tolga Tevfik Sahin; Brian I Carr; Adil Baskiran; Emine Samdanci; Harika Gozukara Bag; Cemalettin Koc; Sertac Usta; Fatih Ozdemir; Bora Barut; Fatih Gonultas; Baris Sarici; Koray Kutluturk; Murat Sait Dogan; Dincer Ozgor; Mustafa Dikilitas; Murat Harputluoglu; Murat Aladag; Ramazan Kutlu; Ilknur Varol; Abuzer Dirican; Cemalettin Aydin; Burak Isik; Cengiz Ara; Cuneyt Kayaalp; Sukru Emre; Sezai Yilmaz Journal: J Gastrointest Cancer Date: 2020-06-05