| Literature DB >> 34881347 |
David P Trofa1, Michael Constant1, Connor R Crutchfield1, Nicholas J Dantzker1, Bryan M Saltzman1, T Sean Lynch1, Christopher S Ahmad1.
Abstract
BACKGROUND: Ulnar collateral ligament (UCL) reconstruction is the current gold standard of treatment for overhead athletes with a symptomatic, deficient UCL of the elbow who have failed nonoperative treatment and wish to return to sport (RTS) at a high level. The palmaris longus and hamstring tendons are common graft choices, but no study has analyzed the existing literature to assess whether one graft is superior to the other.Entities:
Keywords: Tommy John surgery; hamstring; palmaris longus; return to sport (RTS); ulnar collateral ligament
Year: 2021 PMID: 34881347 PMCID: PMC8646802 DOI: 10.1177/23259671211055726
Source DB: PubMed Journal: Orthop J Sports Med ISSN: 2325-9671
Eligibility Criteria
| Inclusion Criteria | Exclusion Criteria |
|---|---|
|
Primary UCLR of elbow Use of the palmaris longus or hamstring tendon grafts Included RTS, failure rates, or PROs as outcomes Controlled trials (randomized and unrandomized) Prospective cohort studies Retrospective cohort studies Minimum 2-year follow-up |
UCLR of thumb Non-English language No reported outcomes Nonhuman studies Basic science investigations Review articles Expert opinions Technique reports Revision UCLR Allografts |
PRO, patient-reported outcome; RTS, return to sport; UCLR, ulnar collateral ligament reconstruction.
Figure 1.PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) flowchart of the study selection process.
Study Characteristics
| Lead Author (Year) | LOE | Enrollment/ | Mean Age, y | Follow-Up, months | Level of Play, % | Technique Used, % | Graft Type, % | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Pro | Collegiate | HS | Rec | Modified Jobe | Docking | Other | Palmaris | Hamstring | Other | |||||
| Arner (2019)
| 3 | 51/51 | 19.6 | 80.4 | 5.88 | 76.47 | 17.65 | 0 | 49.02 | 50.98 | 0 | 70.59 | 29.41 | 0 |
| Cain (2010)
| 4 | 1281/743 | 21.5 | 37 | NA | NA | NA | NA | 100 | 0 | 0 | 74.29 | 23.55 | 2.15 |
| Erickson (2016)
| 3 | 85/85 | 19.3 | 60 | 0 | 49.41 | 41.18 | 9.41 | 0 | 57.65 | 42.35 | 63.53 | 23.53 | 12.94 |
| Griffith (2019)
| 3 | 566/566 | 23.5 | ≥24 | 100 | 0 | 0 | 0 | 51.24 | 30.21 | 18.55 | 63.78 | 23.85 | 12.37 |
| Marshall (2019)
| 2 | 46/46 | 26.3 | 36 | 100 | 0 | 0 | 0 | 60.87 | 36.96 | 2.17 | 76.09 | 23.91 | 0 |
| Saper (2018)
| 4 | 140/140 | 18 | 57.9 | 2.14 | 37.14 | 60 | 0.71 | 100 | 0 | 0 | 77.14 | 21.43 | 1.43 |
HS, high school; LOE, level of evidence; NA, not available. Pro, professional; Rec, recreational
Griffith et al did not specify mean follow-up.
Modified Coleman Methodology Score
| Study | Item (Possible Points) | Total (100) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| No. 1 (10) | No. 2 (5) | No. 3 (5) | No. 4 (10) | No. 5 (15) | No. 6 (5) | No. 7 (5) | No. 8 (5) | No. 9 (10) | No. 10 (15) | No. 11 (15) | ||
| Arner et al
| 4 | 5 | 5 | 10 | 10 | 5 | 5 | 5 | 10 | 11 | 10 | 80 |
| Cain et al
| 10 | 3 | 0 | 10 | 0 | 5 | 3 | 5 | 10 | 3 | 10 | 59 |
| Erickson et al
| 7 | 3 | 5 | 10 | 0 | 5 | 5 | 5 | 10 | 6 | 10 | 66 |
| Griffith et al
| 10 | 0 | 5 | 10 | 0 | 5 | 3 | 0 | 10 | 3 | 10 | 56 |
| Marshall et al
| 4 | 3 | 5 | 10 | 0 | 5 | 3 | 0 | 10 | 3 | 10 | 53 |
| Saper et al
| 10 | 3 | 5 | 10 | 0 | 5 | 3 | 5 | 10 | 3 | 10 | 64 |
| Mean ± SD | 7.5 ± 2.95 | 2.83 ± 1.6 | 4.17 ± 2.04 | 10 ± 0 | 1.67 ± 4.1 | 5 ± 0 | 3.67 ± 1.03 | 3.33 ± 2.58 | 10 ± 0 | 4.83 ± 3.25 | 10 ± 0 | 63 ± 9.63 |
Item descriptions: 1 = study size; 2 = mean follow-up; 3 = percentage of patients with follow-up; 4 = number of interventions per group; 5 = study type; 6 = diagnostic certainty; 7 = description of surgical technique; 8 = description of postoperative rehabilitation; 9 = outcome criteria; 10 = procedure for assessing outcomes; 11 = description of participant selection process.
Figure 2.Modified risk-of-bias assessment.
Figure 3.Funnel-plot analysis of publication bias for return to same level outcomes from 4 studies. OR, odds ratio.
Concomitant Procedures
| Concomitant Procedure | Frequency, % (n/N) | Studies Reporting |
|---|---|---|
| Subcutaneous ulnar nerve transposition | 78.9 (1622/2057) | Cain et al,
|
| Excision of a posteromedial olecranon osteophyte | 19.4 (398/2057) | Cain et al,
|
| Loose body removal | 3.99 (82/2057) | Cain et al,
|
| Ulnar nerve in situ decompression | 2.97 (61/2057) | Griffith et al
|
| Flexor pronator debridement | 1.26 (26/2057) | Cain et al,
|
| Submuscular ulnar nerve transposition | 1.07 (22/2057) | Griffith et al
|
| Excision of calcifications/ossicles | 1.07 (22/2057) | Griffith et al,
|
| Radiocapitellar chondroplasty | 0.53 (11/2057) | Griffith et al
|
| Platelet-rich plasma injection | 0.34 (7/2057) | Griffith et al
|
| Screw fixation of an olecranon stress fracture | 0.19 (4/2057) | Cain et al
|
| Bone marrow aspirate concentrate injection | 0.15 (3/2057) | Griffith et al
|
| Lateral collateral ligament repair | 0.15 (3/2057) | Cain et al
|
| Capsular release | 0.10 (2/2057) | Cain et al
|
| Other | 0.44 (9/2057) | Saper et al
|
Patient-Reported Outcomes by Study
| PRO and Study | Elbows Evaluated | Palmaris Group Score | Hamstring Group Score |
|
|---|---|---|---|---|
| KJOC | ||||
| Arner et al
| 51 | 82.3 ± 20 | 57.9 ± 21.2 |
|
| Erickson et al
| 85 | 90.39 ± 7.06 | 89.62 ± 9.12 | .251 |
| Saper et al
| 140 | NR | NR | >.05 |
| Timmerman-Andrews | ||||
| Erickson et al
| 85 | 91.67 ± 8.59 | 93.75 ± 5.82 | .181 |
| Saper et al
| 140 | NR | NR | >.05 |
| Conway-Jobe | ||||
| Arner et al
| 51 | NR | NR | .49 |
| Saper et al
| 140 | NR | NR | >.05 |
KJOC, Kerlan-Jobe Orthopaedic Clinic; NR, not reported (study analyzed PROs but did not provide scores for individual graft types); PRO, patient-reported outcome. Bold P value indicates statistically significant difference between the palmaris and hamstring groups (P < .05).
Complication and Failure Rates
| Study | Grafts Used | Complications | Failures |
|---|---|---|---|
| Arner et al
| Palmaris, hamstring |
3 transient ulnar nerve irritation (5.9%) 3 medial epicondyle soreness (5.9%) 4 (8%) future elbow surgeries (not revision UCLR) | 0% failure |
| Cain et al4 | Palmaris, hamstring |
121 minor ulnar nerve neurapraxia (16.29%) 27 graft-site complications (3.63%; most commonly superficial infection) 53 reoperations for arthroscopic debridement of olecranon osteophyte (7.1%) | 9 revisions (1.2%) |
| Erickson et al
| Palmaris, hamstring (gracilis) | 8 (9.4%; 6 palmaris [11.1%] and 2 gracilis [10%]) | 6 reoperations (7.1%; 4 palmaris [7.4%] and 2 gracilis [10%]) |
| Griffith et al
| Palmaris, hamstring (gracilis) | 65 subsequent elbow surgeries (11.5%; 46 palmaris [12.7%] and 19 gracilis [14.1%]) | 24 revisions (4.2%; 15 palmaris [4.2%] and 9 gracilis [6.7%]) |
| Marshall et al
| Palmaris, hamstring | NR | NR |
| Saper et al
| Palmaris, hamstring |
1 intraoperative ulnar nerve injury (0.7%) 1 heterotopic ossification and arthrofibrosis requiring surgery within 12 mo (0.7%) 1 excision of a calcium deposit within 12 mo (0.7%) 2 medial epicondyle avulsion fractures (1.4%) | NR |
NR, not reported; UCLR, ulnar collateral ligament reconstruction.
Outcomes reported from 743 patients.
Overall RTS and RSL Rates
| RTS | RSL | |||
|---|---|---|---|---|
| Study | n/N (%) of Patients | Mean Time (mo) | n/N (%) of Patients | Mean Time (mo) |
| Arner et al
| 42/51 (83) | NR | 28/51 (55) | NR |
| Cain et al4 | NR | NR | 610/735 (83) | 11.6 |
| Erickson et al
| NR | NR | 69/74 (93.24) | NR |
| Griffith et al
| 452/566 (79.9) | 14.5 | 403/566 (71.2) | 17.3 |
| Marshall et al
| 43/45 (96) | 13.7 | 36/44 (82) | NR |
| Saper et al
| 135/138 (97.8) | 11.6 | 124/138 (89.9) | NR |
NR, not reported; RSL, return to same level; RTS, return to sport.
Outcomes reported from 743 patients.
RTS and RSL Rates by Graft Type
| Study | Grafts Used | % RTS | % RSL | |||||
|---|---|---|---|---|---|---|---|---|
| Palmaris | Hamstring | Palmaris | Hamstring |
| Palmaris | Hamstring |
| |
| Arner et al
| 36 | 15 | NR | NR | NR | NR | NR | NR |
| Cain et al4 | 552 | 175 | NR | NR | NR | 85.14 | 88 | .3 |
| Erickson et al
| 54 | 20 | NR | NR | NR | 92.59 | 95 | .999 |
| Griffith et al
| 361 | 135 | 83.1 | 80.7 | .596 | 75.4 | 69.9 | .208 |
| Marshall et al
| 35 | 11 | 100 | 82 | .01 | 83 | 73 | .46 |
| Saper et al
| 108 | 30 | NR | NR | NR | NR | NR | NR |
NR, not reported; RSL, return to same level; RTS, return to sport.
Outcomes reported from 743 patients.
Figure 4.Meta-analysis comparing rates of return to same level between the palmaris and gracilis (hamstring) graft groups. M-H, Mantel-Haenszel.