| Literature DB >> 34876152 |
Yuluo Rong1, Chengyue Ji1, Zhuanghui Wang1, Xuhui Ge1, Jiaxing Wang1, Wu Ye1, Pengyu Tang1, Dongdong Jiang1, Jin Fan1, Guoyong Yin1, Wei Liu2, Weihua Cai3.
Abstract
Entities:
Year: 2021 PMID: 34876152 PMCID: PMC8653602 DOI: 10.1186/s12974-021-02336-3
Source DB: PubMed Journal: J Neuroinflammation ISSN: 1742-2094 Impact factor: 8.322
Fig. 6CCL2-induced microglial activation may aggravate neuronal apoptosis. A, B Western blotting detection of IL-1Ra protein expression in spinal cord tissue. C Immunofluorescence detection of IL-1Ra protein expression in neuronal cells
Fig. 7The CCR2 antagonist INCB3344 decreases microglial activation and neuronal apoptosis after SCI. A–H ELISA, qRT-PCR and western blotting evaluation of spinal cord TNF-α, IL-1β and IL-6 expression. I Immunofluorescence staining to detect the expression of the microglial activation marker OX42. J, K TUNEL staining to detect spinal cord apoptosis. L, M Western blotting to detect spinal cord apoptosis related protein expression