Literature DB >> 34876152

Correction to: Small extracellular vesicles encapsulating CCL2 from activated astrocytes induce microglial activation and neuronal apoptosis after traumatic spinal cord injury.

Yuluo Rong1, Chengyue Ji1, Zhuanghui Wang1, Xuhui Ge1, Jiaxing Wang1, Wu Ye1, Pengyu Tang1, Dongdong Jiang1, Jin Fan1, Guoyong Yin1, Wei Liu2, Weihua Cai3.   

Abstract

Entities:  

Year:  2021        PMID: 34876152      PMCID: PMC8653602          DOI: 10.1186/s12974-021-02336-3

Source DB:  PubMed          Journal:  J Neuroinflammation        ISSN: 1742-2094            Impact factor:   8.322


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Correction to: J Neuroinflamm (2021) 18:196 https://doi.org/10.1186/s12974-021-02268-y

Following publication of the original article [1], the author noticed that Figs. 6 and 7 of the published version of this article were incorrectly uploaded. Presented here are the corrected Figs. 6 and  7.
Fig. 6

CCL2-induced microglial activation may aggravate neuronal apoptosis. A, B Western blotting detection of IL-1Ra protein expression in spinal cord tissue. C Immunofluorescence detection of IL-1Ra protein expression in neuronal cells

Fig. 7

The CCR2 antagonist INCB3344 decreases microglial activation and neuronal apoptosis after SCI. A–H ELISA, qRT-PCR and western blotting evaluation of spinal cord TNF-α, IL-1β and IL-6 expression. I Immunofluorescence staining to detect the expression of the microglial activation marker OX42. J, K TUNEL staining to detect spinal cord apoptosis. L, M Western blotting to detect spinal cord apoptosis related protein expression

CCL2-induced microglial activation may aggravate neuronal apoptosis. A, B Western blotting detection of IL-1Ra protein expression in spinal cord tissue. C Immunofluorescence detection of IL-1Ra protein expression in neuronal cells The CCR2 antagonist INCB3344 decreases microglial activation and neuronal apoptosis after SCI. A–H ELISA, qRT-PCR and western blotting evaluation of spinal cord TNF-α, IL-1β and IL-6 expression. I Immunofluorescence staining to detect the expression of the microglial activation marker OX42. J, K TUNEL staining to detect spinal cord apoptosis. L, M Western blotting to detect spinal cord apoptosis related protein expression
  1 in total

1.  Small extracellular vesicles encapsulating CCL2 from activated astrocytes induce microglial activation and neuronal apoptosis after traumatic spinal cord injury.

Authors:  Yuluo Rong; Chengyue Ji; Zhuanghui Wang; Xuhui Ge; Jiaxing Wang; Wu Ye; Pengyu Tang; Dongdong Jiang; Jin Fan; Guoyong Yin; Wei Liu; Weihua Cai
Journal:  J Neuroinflammation       Date:  2021-09-12       Impact factor: 8.322

  1 in total

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