| Literature DB >> 34871091 |
Etienne Bizot1, Aurélie Cointe1,2, Philippe Bidet1,2, Patricia Mariani-Kurkdjian1, Claire Amaris Hobson2, Céline Courroux1, Sandrine Liguori1, Antoine Bridier-Nahmias2, Mélanie Magnan2, Manel Merimèche2,3, François Caméléna2,3, Béatrice Berçot2,3, François-Xavier Weill4, Sophie Lefèvre4, Stéphane Bonacorsi1,2, André Birgy1,2.
Abstract
We described and characterized Shiga-toxin-producing Escherichia coli (STEC) strains with high levels of resistance to azithromycin isolated in France between 2004 and 2020. Nine of 1,715 (0.52%) STEC strains were resistant to azithromycin, with an increase since 2017. One isolate carried a plasmid-borne mef(C)-mph(G) gene combination, described here for the first time for E. coli. Azithromycin resistance, although rare, needs consideration, as this treatment may be useful in cases of STEC infection.Entities:
Keywords: EHEC; azithromycin resistance; fosfomycin; macrolide resistance; macrolides; mef(C)-mph(G); mph(A); mph(B); phosphorylases; rifaximin
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Year: 2021 PMID： 34871091 PMCID： PMC8846429 DOI： 10.1128/AAC.01949-21
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.938