Literature DB >> 34870632

The Anesthesiologist as Translational Scientist.

Keren K Griffiths1, Adam Gerber, Robert A Whittington.   

Abstract

Translational science seeks to accelerate the multi-step process by which scientific discoveries are transformed into therapies that can improve the health of individuals and their communities. To facilitate crossing the traditional boundaries between basic and clinical research for instance, a systematic understanding of the scientific and operational principles that underlie each step of the translational cycle is developed to identify and address barriers to translation. Skills required by translational scientists, such as being systems thinkers and process innovators, overlap with those of anesthesiologists, and therefore, it is no surprise that anesthesiologists have contributed to this field. Indeed, the safety and efficacy of anesthesia care has greatly evolved over many decades because anesthesiologists have recognized the importance of readily incorporating physiological and pharmacological basic research findings into clinical practice. This article highlights the characteristics that make anesthesiologists well suited to be translational scientists. We also discuss one example of anesthesiology contributing to the field of translational science during the COVID-19 pandemic. We show that anesthesiologists, regardless of their specific clinical or research interests, have the skill set to become effective and critical players in the field of translational science and emphasize the importance of continued leadership in this field to academic anesthesiology.
Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.

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Year:  2022        PMID: 34870632      PMCID: PMC8653981          DOI: 10.1097/ANA.0000000000000807

Source DB:  PubMed          Journal:  J Neurosurg Anesthesiol        ISSN: 0898-4921            Impact factor:   3.956


  8 in total

1.  Clinical and translational science: from bench-bedside to global village.

Authors:  Scott A Waldman; Andre Terzic
Journal:  Clin Transl Sci       Date:  2010-10       Impact factor: 4.689

2.  Anesthesiology comes of age.

Authors:  E M Papper
Journal:  JAMA       Date:  1989-09-01       Impact factor: 56.272

3.  Perioperative neuroscience: a framework for clinical and scientific advancement.

Authors:  Phillip E Vlisides
Journal:  Br J Anaesth       Date:  2019-05-20       Impact factor: 9.166

4.  The Fundamental Characteristics of a Translational Scientist.

Authors:  C Taylor Gilliland; Julia White; Barry Gee; Rosan Kreeftmeijer-Vegter; Florence Bietrix; Anton E Ussi; Marian Hajduch; Petr Kocis; Nobuyoshi Chiba; Ryutaro Hirasawa; Makoto Suematsu; Justin Bryans; Stuart Newman; Matthew D Hall; Christopher P Austin
Journal:  ACS Pharmacol Transl Sci       Date:  2019-05-02

5.  Anaesthesiologists as translational scientists.

Authors:  Jim G Castellanos; Alexendar R Perez; Richard K Perez
Journal:  Br J Anaesth       Date:  2020-01-27       Impact factor: 9.166

6.  Ralph Waters and the beginnings of academic anesthesiology in the United States: the Wisconsin Template.

Authors:  D R Bacon; R Ament
Journal:  J Clin Anesth       Date:  1995-09       Impact factor: 9.452

7.  Reengineering the national clinical and translational research enterprise: the strategic plan of the National Clinical and Translational Science Awards Consortium.

Authors:  Steven E Reis; Lars Berglund; Gordon R Bernard; Robert M Califf; Garret A Fitzgerald; Peter C Johnson
Journal:  Acad Med       Date:  2010-03       Impact factor: 6.893

Review 8.  Repurposing of Drugs-The Ketamine Story.

Authors:  Joydip Das
Journal:  J Med Chem       Date:  2020-09-22       Impact factor: 7.446

  8 in total

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