Literature DB >> 34865416

Re: Comments on "Chorea as a Presentation of SARS-CoV-2 Encephalitis: A Clinical Case Report".

Muhammad Hassan1, Naveed Ullah Khan1, Mazhar Badshah1.   

Abstract

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Year:  2021        PMID: 34865416      PMCID: PMC8820890          DOI: 10.14802/jmd.21111

Source DB:  PubMed          Journal:  J Mov Disord        ISSN: 2005-940X


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Dear Editor, The accurate differential diagnosis between myoclonus and chorea by neurological examination without electrophysiological studies is occasionally difficult, since not only myoclonus but also chorea may present irregular jerky movements. Myoclonus is defined as a sudden, brief, lightning-like muscle contraction. Furthermore, myoclonus includes both muscular contraction phenomenology (positive myoclonus) and inhibition of muscular contraction phenomenology (negative myoclonus) [1]. There are various etiologies and pathogenesis of myoclonus, most often categorized into cortical, subcortical, or spinal myoclonus. However, the pathophysiology of chorea is mainly implicated in dysfunction of the basal ganglia motor circuitry. The first video of the patient showed abnormal movements that were involuntary, abrupt, nonstereotyped, irregular, sometimes large-amplitude, and unpredictable on the right leg and arm, defined as chorea by the authors [2]. However, as pointed out in the letter [3], myoclonus was also observed in the first video, and all abnormal movements in the other videos appear to be myoclonus [2]. Therefore, the patient may have a combination of abnormal movements due to both myoclonus and chorea.
  2 in total

1.  Chorea as a Presentation of SARS-CoV-2 Encephalitis: A Clinical Case Report.

Authors:  Muhammad Hassan; Fibhaa Syed; Liaqat Ali; Haris Majid Rajput; Farhan Faisal; Waleed Shahzad; Mazhar Badshah
Journal:  J Mov Disord       Date:  2021-03-15

2.  Comment on "Chorea as a Presentation of SARS-CoV-2 Encephalitis: A Clinical Case Report".

Authors:  Ruth H Walker
Journal:  J Mov Disord       Date:  2021-12-07
  2 in total

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