Patricia A Parmelee1, Emily A Behrens1, Kyrsten Costlow Hill1, Brian S Cox1, Jason A DeCaro2, Francis J Keefe3, Dylan M Smith4. 1. Alabama Research Institute on Aging and Department of Psychology, The University of Alabama, Tuscaloosa, Alabama, USA. 2. Department of Anthropology, The University of Alabama, Tuscaloosa, Alabama, USA. 3. Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, North Carolina, USA. 4. Program in Public Health and Department of Family, Population, and Preventive Medicine, Stony Brook University, Stony Brook, New York, USA.
Abstract
OBJECTIVES: This research examined main and moderating effects of global depressive symptoms upon in-the-moment associations of pain and affect among individuals with knee osteoarthritis (OA). Effects of depression on short-term change in pain and affect were also examined. METHOD: Older adults with physician-confirmed OA (N = 325) completed a baseline interview tapping global depressive symptoms, followed by an experience sampling protocol that captured momentary pain and affect 4 times daily for 7 days. Multilevel models controlling demographics and health conditions examined main and moderating effects of depression on momentary associations of pain with positive affect (PA) and negative affect (NA). Similar methods addressed short-term change in pain and affect. Auxiliary analyses explored broad associations of depressive symptoms with person-level averages and variability in pain and affect. RESULTS: Global depression predicted current pain, PA, and NA, as well as change in pain and affect over a 3- to 8-h period. Furthermore, both in the moment and over short periods, the association of pain and NA was stronger among persons higher in depressive symptoms. No moderating effect for the PA-pain association was found. Depressive symptoms were also associated with variability in pain and affect, particularly NA. DISCUSSION: Results confirm previous work on the relation of chronic pain with both global depressive symptoms and short-term affect. This research further demonstrates a unique moderating role of depression on the association of momentary pain with NA and suggests that the causal path may be stronger from pain to affect than vice versa.
OBJECTIVES: This research examined main and moderating effects of global depressive symptoms upon in-the-moment associations of pain and affect among individuals with knee osteoarthritis (OA). Effects of depression on short-term change in pain and affect were also examined. METHOD: Older adults with physician-confirmed OA (N = 325) completed a baseline interview tapping global depressive symptoms, followed by an experience sampling protocol that captured momentary pain and affect 4 times daily for 7 days. Multilevel models controlling demographics and health conditions examined main and moderating effects of depression on momentary associations of pain with positive affect (PA) and negative affect (NA). Similar methods addressed short-term change in pain and affect. Auxiliary analyses explored broad associations of depressive symptoms with person-level averages and variability in pain and affect. RESULTS: Global depression predicted current pain, PA, and NA, as well as change in pain and affect over a 3- to 8-h period. Furthermore, both in the moment and over short periods, the association of pain and NA was stronger among persons higher in depressive symptoms. No moderating effect for the PA-pain association was found. Depressive symptoms were also associated with variability in pain and affect, particularly NA. DISCUSSION: Results confirm previous work on the relation of chronic pain with both global depressive symptoms and short-term affect. This research further demonstrates a unique moderating role of depression on the association of momentary pain with NA and suggests that the causal path may be stronger from pain to affect than vice versa.
Authors: Chantal Berna; Siri Leknes; Emily A Holmes; Robert R Edwards; Guy M Goodwin; Irene Tracey Journal: Biol Psychiatry Date: 2010-03-29 Impact factor: 13.382
Authors: Orit Schieir; Brett D Thombs; Marie Hudson; Suzanne Taillefer; Russell Steele; Laeora Berkson; Carole Bertrand; Francois Couture; Mary-Ann Fitzcharles; Michel Gagné; Bruce Garfield; Andrzej Gutkowski; Harb Kang; Morton Kapusta; Sophie Ligier; Jean-Pierre Mathieu; Henri Ménard; Suzanne Mercille; Michael Starr; Michael Stein; Michel Zummer; Murray Baron Journal: J Rheumatol Date: 2009-02 Impact factor: 4.666