Causes and consequences of circulatory changes in renal transplants. I. Angiographic studies.

Selective angiography post mortem and in vivo, respectively, has been performed in canine kidneys (isolated, autografted or left in situ) for the study of the renovascular changes caused by different perfusates and by reperfusion. The results indicate that inadequate heparinization, the composition of the perfusate, imperfect surgical techniques and even restoration of circulation to the kidney itself, may produce roentgenologically demonstrable renovascular damage the causes and consequences of which are unrelated to those of the closely studied and adequately interpreted phenomena of graft rejection.