Literature DB >> 3485852

Ototoxicity of the antiseptic combination chlorhexidine/cetrimide (Savlon): effects on equilibrium and hearing.

H G Gallé, A J Venker-van Haagen.   

Abstract

Literature concerning the ototoxicity of the antiseptic combination chlorhexidine/cetrimide (Savlon) is reviewed. The ototoxic effects are illustrated by the results of our own experiments in guinea pigs. The impetus for this article was the observation of vestibular dysfunction in 15 clinical cases (12 dogs and 3 cats), in 8 of which it was confirmed that the ear canal had been rinsed with this drug combination in the presence of a ruptured tympanic membrane.

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Year:  1986        PMID: 3485852     DOI: 10.1080/01652176.1986.9694018

Source DB:  PubMed          Journal:  Vet Q        ISSN: 0165-2176            Impact factor:   3.320


  2 in total

Review 1.  Systematic review of ototoxic pre-surgical antiseptic preparations - what is the evidence?

Authors:  Shubhi Singh; Brian Blakley
Journal:  J Otolaryngol Head Neck Surg       Date:  2018-03-01

Review 2.  Feline vestibular disorders. Part II: diagnostic approach and differential diagnosis.

Authors:  K M Vernau; R A LeCouteur
Journal:  J Feline Med Surg       Date:  1999-06       Impact factor: 2.015

  2 in total

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